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NCT00815204 · ClinicalTrials.gov registry record
Measurement of Pituitary Volume and Hormonal Changes in Patients With Post-traumatic Stress Disorder
A clinical trial of Post Traumatic Stress Disorder, sponsored by Cedars-Sinai Medical Center.
- Completed
- Registry status
- 39
- Enrollment target
- 1
- Study location
NCT00815204: Completed study of Post Traumatic Stress Disorder, sponsored by Cedars-Sinai Medical Center.
NCT00815204 is a study of Post Traumatic Stress Disorder that has completed, run by Cedars-Sinai Medical Center. The registered enrollment target is 39 participants, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00815204, a study of Post Traumatic Stress Disorder, has completed, sponsored by Cedars-Sinai Medical Center.
- COMPLETED
- Registry status
- 39 participants
- Enrollment target
- 1
- Study location
Study Summary
Approximately, post-traumatic stress disorder (PTSD) occurs in 8% of the adult population over time. Exposure to traumatic events increases the risk of poor physical health and often leads to disability. The biology of PTSD is continually being explored in order to help find better treatments for this debilitating disorder. In our study, we propose to further our understanding of PTSD. Prior research has found that patients with PTSD have changes in the stress hormone pathway. In this pathway, there is release of certain hormones from the pituitary gland in the brain that feed into the blood stream and tell the adrenal gland to produce stress hormones. The pituitary is a gland located at the base of the brain which controls the hormones in the body, including the stress hormones. Research in other psychiatric disorders has found changes in the pituitary volume along with changes in the hormones. This has not been investigated yet in PTSD. Therefore, we propose in our study to measure pituitary volume in people with PTSD and look at the changes in the stress hormone pathway. Moreover, we will investigate whether other hormones are affected by PTSD. In this way, we can further our understanding of the the biology of PTSD and help develop new therapies which can intervene through the hormonal system.
Conditions Studied
Interventions
- PROCEDURE MRI of the pituitary
- PROCEDURE DEX/CRH test
Study Locations (1)
California
- Cedars-Sinai Medical Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2008-05 |
| Est. Completion | 2014-07 |
What the finished NCT00815204 record still lists
NCT00815204 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 664-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which MRI of the pituitary is the first listed.
NCT00815204 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT00815204 about?
NCT00815204 is a clinical study titled "Measurement of Pituitary Volume and Hormonal Changes in Patients With Post-traumatic Stress Disorder". Approximately, post-traumatic stress disorder (PTSD) occurs in 8% of the adult population over time. Exposure to traumatic events increases the risk of poor physical health and often leads to disability. The biology of PTSD is continually being explored in order to help find better treatments for th...
What is the current status of trial NCT00815204?
This trial is currently completed. The enrollment target is 39 participants. The study started on 2008-05. Estimated completion is 2014-07.
What conditions does trial NCT00815204 study?
This clinical trial studies the following conditions: Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT00815204?
The interventions under investigation include: MRI of the pituitary (PROCEDURE), DEX/CRH test (PROCEDURE).
Who is sponsoring clinical trial NCT00815204?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00815204 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00815204's enrollment target sits among peer trials
39 199th of 262 higher than 64 of 262 other Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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