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NCT00366457 · ClinicalTrials.gov registry record · Phase 2

Gemcitabine, Bevacizumab and Erlotinib in Pancreatic Cancer

A Phase 2 study of Pancreatic Cancer and Adenocarcinoma of the Pancreas, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
32
Enrollment target
3
Study locations

NCT00366457 is a Phase 2 study of Pancreatic Cancer and Adenocarcinoma of the Pancreas that has completed, run by Massachusetts General Hospital. The registered enrollment target is 32 participants, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (92% lower). The trial reports 3 study locations across 1 state.

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The verdict

NCT00366457, a Phase 2 study of Pancreatic Cancer and Adenocarcinoma of the Pancreas, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
32 participants
Enrollment target
3
Study locations

Study Summary

The main purpose of this study is to learn whether or not the combination of gemcitabine, bevacizumab and erlotinib works in treating patients with advanced or metastatic pancreatic cancer. Bevacizumab is a new anti-cancer drug. It is an antibody that works to slow or stop cell growth in cancerous tumors by decreasing the blood supply to the tumors. It is approved by the FDA for the treatment of colorectal cancer but is still considered investigational for treating pancreatic cancer.

Interventions

  • DRUG Bevacizumab
  • DRUG Gemcitabine
  • DRUG Erlotinib

Study Locations (3)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Beth Israel Deaconess Medical Center - Boston
  • Dana-Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2006-08
Est. Completion 2011-07
Phase Phase 2

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT00366457

The ClinicalTrials.gov registry entry for NCT00366457 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (92% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pancreatic Cancer appearing as the primary indexed condition, and to 3 interventions - of which Bevacizumab is the first listed.

NCT00366457 reports 3 study locations spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT00366457 about?

NCT00366457 is a clinical study titled "Gemcitabine, Bevacizumab and Erlotinib in Pancreatic Cancer". The main purpose of this study is to learn whether or not the combination of gemcitabine, bevacizumab and erlotinib works in treating patients with advanced or metastatic pancreatic cancer. Bevacizumab is a new anti-cancer drug. It is an antibody that works to slow or stop cell growth in cancerous t...

What is the current status of trial NCT00366457?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 32 participants. The study started on 2006-08. Estimated completion is 2011-07.

What conditions does trial NCT00366457 study?

This clinical trial studies the following conditions: Pancreatic Cancer, Adenocarcinoma of the Pancreas.

What interventions are being tested in trial NCT00366457?

The interventions under investigation include: Bevacizumab (DRUG), Gemcitabine (DRUG), Erlotinib (DRUG).

Who is sponsoring clinical trial NCT00366457?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00366457 being conducted?

This trial has 3 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.