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ClinicalTrials.gov 13 recruiting now early-phase tilt

Oxidative Stress: early-phase trial registry

13 of 37 indexed Oxidative Stress trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #406 of 28,707 conditions by registered trial count.

37 US clinical trials · 13 currently recruiting · #406 of 28,707 conditions by registered trial count

Oxidative Stress: 37 US clinical trials tracked, 13 recruiting.

Oxidative Stress is the subject of 37 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, Davis, running 3 of these trials.

Enrollment posture brief

Registry condition oxidative-stress

OPEN 13 | RECR 35% | LATE 0 | EARLY 9 | RANK #406 | SPON 3

Nearest open-share peer: Anatomic Stage IIIA Breast Cancer AJCC v8 (35% recruiting · 40 trials)

Biliary Tract Cancer64.9%Breastfeeding45.9%Oxidative Stress (this)35%Chronic Obstructive Pulmonar29.7%Burns24.3%
Open-enrollment share among volume-matched conditions near Oxidative Stress

Oxidative Stress lists 13 open slots (35% of 37 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Oxidative Stress on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Oxidative Stress is recruiting below its size-band peers.

    13 of 37 indexed trials (35.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Oxidative Stress trials is spread across many organizations.

    University of California, Davis accounts for 3 of 37 trials (8.1%). 30 distinct sponsors appear on at least one study for this condition label.

  3. Most Oxidative Stress trials plan to enrol fewer than 100 people.

    Median target enrolment is 40 among the 37 trials that report a genuine target (sentinel values excluded). 31 of those (83.8%) plan for fewer than 100 participants.

  4. Oxidative Stress research is mostly interventional.

    33 interventional and 4 observational studies make up this index (89.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 23

Open and recent trials

37 total, page 1 of 1

RECRUITING 1,100 participants

The ROAR Study: Reactive Oxygen Species and Reproduction

University of California, San Francisco

NCT06831019

RECRUITING NA 300 participants

Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

University of Iowa

NCT07244809

RECRUITING Phase 2 118 participants

Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD

University of Colorado, Denver

NCT04040959

RECRUITING NA 110 participants

The Effects of Endotracheal Suctioning on Pain and Serum Markers

Loma Linda University

NCT06692400

RECRUITING 100 participants

Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response

University of Colorado, Denver

NCT02480283

RECRUITING NA 80 participants

Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

Georgia State University

NCT06735599

RECRUITING NA 72 participants

Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse

Joel Trinity

NCT04351113

RECRUITING NA 70 participants

The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

Nathaniel Jenkins

NCT06454344

RECRUITING Early Phase 1 40 participants

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

Anna Stanhewicz, PhD

NCT05946798

RECRUITING 34 participants

Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

University of Minnesota

NCT02437396

RECRUITING NA 30 participants

Impact of Haskap Berries on Recovery From High Intensity Resistance Training

Montana State University

NCT07344727

RECRUITING NA 30 participants

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Georgia State University

NCT06735651

RECRUITING NA 5 participants

Chardonnay Marc and Vascular Response

University of California, Davis

NCT05545865

ACTIVE NOT RECRUITING NA 31 participants

The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes

Loma Linda University

NCT06159543

COMPLETED NA 114 participants

Effects of Taking Prenatal Vitamin-mineral Supplements During Lactation on Iron Status and Markers of Oxidation

University of California, Davis

NCT01047098

COMPLETED NA 88 participants

Trial of a Limited Versus Traditional Oxygen Strategy During Resuscitation in Premature Newborns

University of Texas Southwestern Medical Center

NCT01697904

COMPLETED NA 84 participants

Efficacy of Solarplast for Health and Oxidative Stress

Deerland Enzymes

NCT04144777

COMPLETED Phase 2 80 participants

Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative Stress

University of Mississippi Medical Center

NCT01267227

COMPLETED NA 75 participants

Saturation Targets and Resuscitation in Preterm Trial

University of Texas Southwestern Medical Center

NCT03115463

COMPLETED NA 60 participants

Maternal Oxygen Use During Delivery and Cord Blood Superoxide Dismutase

George Washington University

NCT01042262

COMPLETED NA 56 participants

Effect of Dietary Glycemic Index on Beta-cell Function

Seattle Institute for Biomedical and Clinical Research

NCT01386645

COMPLETED 52 participants

Urinary 8-isoprostane is Elevated in Acute Childhood Asthma

Stony Brook University

NCT01472471

COMPLETED NA 42 participants

Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes

In-Young Choi, Ph.D.

NCT00845130

COMPLETED Phase 2 40 participants

Oxytocin for Oxidative Stress and Inflammation

Florida Institute for Human and Machine Cognition

NCT04732247

COMPLETED NA 40 participants

The Effect of Protandim Supplementation on Oxidative Damage and Athletic Performance

University of Louisville

NCT02172625

COMPLETED NA 37 participants

Acute Effects of TCIG vs ECIG in PLWH

University of California, Los Angeles

NCT04568395

COMPLETED NA 35 participants

Feeding the Critically Ill During Phases of Altered Redox Status

University of Illinois at Chicago

NCT03085615

COMPLETED NA 25 participants

The Long-term Effects of Oceanix™ on Resistance Training Adaptations

Applied Science & Performance Institute

NCT04136821

COMPLETED Phase 1 24 participants

N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults

Indiana University

NCT01962961

COMPLETED Phase 1 24 participants

Safety and Tolerability of Antioxidant (AT-001)for Reducing Brain Oxidative Stress

Alltech Life Sciences

NCT01731093

COMPLETED Early Phase 1 20 participants

Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.

University of California, San Diego

NCT03368352

COMPLETED NA 20 participants

The Effects Grapes on Health Indices

University of California, Davis

NCT01674231

COMPLETED Phase 1 15 participants

Physiological Effects of Grape Seed Extract in Diastolic Heart Failure

University of Michigan

NCT01185067

COMPLETED NA 15 participants

Metabolic Effects of Chemical Interactions in Toxicity

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00253773

COMPLETED NA 12 participants

Creatine Monohydrate Supplementation and Vascular Endothelial Health

Florida State University

NCT05014659

COMPLETED Phase 1 10 participants

Flaxseed Modulates Inflammation and Oxidative Stress in CF

University of Pennsylvania

NCT02014181

COMPLETED NA 8 participants

A Pilot Randomized Controlled Trial of the Effects of Daily Skin-to-skin Contact (PRCTS2S)

University of California, San Francisco

NCT04368767

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3

Named interventions

Most-linked intervention names on Oxidative Stress records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Dietary supplement
5 trials
Wild Blueberry Dietary supplement
2 trials
Placebo Other
2 trials
Placebo Drug
2 trials
Solarplast Dietary supplement
1 trials
Pterostilbene 125 mg twice daily Drug
1 trials
Grape Extract Drug
1 trials
Pterostilbene 50 mg twice daily Drug
1 trials

US sites by state

Facility locations filed on Oxidative Stress trials. A trial with sites in several states counts in each.

California 9 trials
Georgia 4 trials
Iowa 3 trials
Florida 3 trials
Texas 2 trials
Kentucky 2 trials
Colorado 2 trials
Washington 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Oxidative Stress page

37 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Oxidative Stress condition card totals 37 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.