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2026 data Public-data reference. official source

Oxidative Stress

Open-data reference.

37 US clinical trials · 13 currently recruiting

Active & Recent Trials

RECRUITING 1,100 participants

The ROAR Study: Reactive Oxygen Species and Reproduction

University of California, San Francis

NCT06831019

RECRUITING NA 300 participants

Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

University of Iowa

NCT07244809

RECRUITING Phase 2 118 participants

Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD

University of Colorado, Denver

NCT04040959

RECRUITING NA 110 participants

The Effects of Endotracheal Suctioning on Pain and Serum Markers

Loma Linda University

NCT06692400

RECRUITING 100 participants

Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response

University of Colorado, Denver

NCT02480283

RECRUITING NA 80 participants

Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

Georgia State University

NCT06735599

RECRUITING NA 72 participants

Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse

Joel Trinity

NCT04351113

RECRUITING NA 70 participants

The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

Nathaniel Jenkins

NCT06454344

RECRUITING Early Phase 1 40 participants

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

Anna Stanhewicz, PhD

NCT05946798

RECRUITING 34 participants

Oxidative Stress and Inflammatory Biomarkers in Gaucher Disease

University of Minnesota

NCT02437396

RECRUITING NA 30 participants

Impact of Haskap Berries on Recovery From High Intensity Resistance Training

Montana State University

NCT07344727

RECRUITING NA 30 participants

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Georgia State University

NCT06735651

RECRUITING NA 5 participants

Chardonnay Marc and Vascular Response

University of California, Davis

NCT05545865

ACTIVE NOT RECRUITING NA 31 participants

The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes

Loma Linda University

NCT06159543

COMPLETED NA 114 participants

Effects of Taking Prenatal Vitamin-mineral Supplements During Lactation on Iron Status and Markers of Oxidation

University of California, Davis

NCT01047098

COMPLETED NA 88 participants

Trial of a Limited Versus Traditional Oxygen Strategy During Resuscitation in Premature Newborns

University of Texas Southwestern Medical Center

NCT01697904

COMPLETED NA 84 participants

Efficacy of Solarplast for Health and Oxidative Stress

Deerland Enzymes

NCT04144777

COMPLETED Phase 2 80 participants

Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative Stress

University of Mississippi Medical Center

NCT01267227

COMPLETED NA 75 participants

Saturation Targets and Resuscitation in Preterm Trial

University of Texas Southwestern Medical Center

NCT03115463

COMPLETED NA 60 participants

Maternal Oxygen Use During Delivery and Cord Blood Superoxide Dismutase

George Washington University

NCT01042262

COMPLETED NA 56 participants

Effect of Dietary Glycemic Index on Beta-cell Function

Seattle Institute for Biomedical and Clinical Research

NCT01386645

COMPLETED 52 participants

Urinary 8-isoprostane is Elevated in Acute Childhood Asthma

Stony Brook University

NCT01472471

COMPLETED NA 42 participants

Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes

In-Young Choi, Ph.D.

NCT00845130

COMPLETED Phase 2 40 participants

Oxytocin for Oxidative Stress and Inflammation

Florida Institute for Human and Machine Cognition

NCT04732247

COMPLETED NA 40 participants

The Effect of Protandim Supplementation on Oxidative Damage and Athletic Performance

University of Louisville

NCT02172625

COMPLETED NA 37 participants

Acute Effects of TCIG vs ECIG in PLWH

University of California, Los Angeles

NCT04568395

COMPLETED NA 35 participants

Feeding the Critically Ill During Phases of Altered Redox Status

University of Illinois at Chicago

NCT03085615

COMPLETED NA 25 participants

The Long-term Effects of Oceanix™ on Resistance Training Adaptations

Applied Science & Performance Institute

NCT04136821

COMPLETED Phase 1 24 participants

N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults

Indiana University

NCT01962961

COMPLETED Phase 1 24 participants

Safety and Tolerability of Antioxidant (AT-001)for Reducing Brain Oxidative Stress

Alltech Life Sciences

NCT01731093

COMPLETED Early Phase 1 20 participants

Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.

University of California, San Diego

NCT03368352

COMPLETED NA 20 participants

The Effects Grapes on Health Indices

University of California, Davis

NCT01674231

COMPLETED Phase 1 15 participants

Physiological Effects of Grape Seed Extract in Diastolic Heart Failure

University of Michigan

NCT01185067

COMPLETED NA 15 participants

Metabolic Effects of Chemical Interactions in Toxicity

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00253773

COMPLETED NA 12 participants

Creatine Monohydrate Supplementation and Vascular Endothelial Health

Florida State University

NCT05014659

COMPLETED Phase 1 10 participants

Flaxseed Modulates Inflammation and Oxidative Stress in CF

University of Pennsylvania

NCT02014181

COMPLETED NA 8 participants

A Pilot Randomized Controlled Trial of the Effects of Daily Skin-to-skin Contact (PRCTS2S)

University of California, San Francis

NCT04368767

Phase Distribution

PhaseTrial count
Early Phase 1 6
Phase 2 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Oxidative Stress Trial Landscape

ClinicalTrials.gov lists 37 US studies indexed under Oxidative Stress, and 13 of those are currently open to recruitment — roughly 35% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Oxidative Stress shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Oxidative Stress is led by University of California, Davis with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 37 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Oxidative Stress?

PlainTrial tracks 37 US clinical trials for Oxidative Stress, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Oxidative Stress?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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