Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Burns
Open-data reference.
37 US clinical trials · 9 currently recruiting
Active & Recent Trials
Understanding the Burn Wound Microbiome: Comparing Traditional Wound Cultures to Next Generation Sequencing Technology
The University of Texas Medical Branch, Galveston
NCT05275335
4-Aminopyridine to Treat Skin Burns
John Elfar
NCT06596434
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
University of Kansas Medical Center
NCT03854344
Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
University of Kansas Medical Center
NCT06379724
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
Skingenix
NCT01297400
Impact of a Telerehabilitation Program With Technology Enhancement on Post-burn Recovery
The University of Texas Medical Branch, Galveston
NCT06162052
Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers
The Metis Foundation
NCT05217160
Suprathel® Use During Prolonged Field Care to Promote Healing and Reduce the Need for Grafting of Burn Wounds
The Metis Foundation
NCT05462860
Microsurfaced Grafts in Deep Burn Wounds
CellTherX
NCT04589442
Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns
PolyNovo Biomaterials Pty
NCT04090424
Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation
Spaulding Rehabilitation Hospital
NCT05351333
Inflammation and the Host Response to Injury (Trauma)
Massachusetts General Hospital
NCT00257231
Inflammation and the Host Response to Injury (Burns)
Massachusetts General Hospital
NCT00257244
DeepView SnapShot Portable (DV-SSP): Device Training Study
SpectralMD
NCT05023135
Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)
Cumberland Pharmaceuticals
NCT00061633
A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries
Avita Medical
NCT01138917
SSD vs Collagenase in Pediatric Burn Patients
Children's Mercy Hospital Kansas City
NCT00787592
Effect of Burn Size on Cytomegalovirus Reactivation and Correlates of T Cell Immune Function in Burned Patients
University of North Carolina, Chapel Hill
NCT00467532
VR for Burn Dressing Changes at Home
Nationwide Children's Hospital
NCT04548635
StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns
Stratatech, a Mallinckrodt Company
NCT01437852
Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound Dressing
Molnlycke Health Care AB
NCT01214811
Virtual Reality in Burn Pain Management
United States Army Institute of Surgical Research
NCT00593086
Vashe Wound Therapy Study
Valleywise Health
NCT00586729
Patient-Controlled Anxiolysis With Dexmedetomidine (PCA-DEX) for Burn-care Dressing Changes
Ohio State University
NCT02409810
Cranial Electrotherapy Stimulation in Burned Patients
United States Army Institute of Surgical Research
NCT00723008
Effect of rFVIIa on Peri-operative Blood Loss in Patients Undergoing Major Burn
United States Army Institute of Surgical Research
NCT00243243
Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients
Massachusetts General Hospital
NCT01500655
Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar
Massachusetts General Hospital
NCT03692273
Assessment of Safety and Effectiveness of Biodegradable Temporizing Matrix in the Treatment of Deep Burn Skin Injuries
PolyNovo Biomaterials Pty
NCT02905435
Burn Outcomes in Young Adult Burn Survivors
Massachusetts General Hospital
NCT01254357
VR for Pain Management During Adult Burn Dressing Change
Nationwide Children's Hospital
NCT04545229
Virtual Reality Hypnosis for Chronic Pain Reduction
University of Washington
NCT01099657
Comparison of Wound Bed Establishment in Facial Burns
University of Louisville
NCT01668030
Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery
University of Kansas Medical Center
NCT03513406
Amnion Wound Covering for Enhanced Wound Healing
Wake Forest University Health Sciences
NCT03754218
Safety of Extracellular Vesicles for Burn Wounds
Aegle Therapeutics
NCT05078385
StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects
Stratatech, a Mallinckrodt Company
NCT05517902
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 4 |
| Phase 2 | 5 |
| Phase 3 | 4 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Burns Trial Landscape
ClinicalTrials.gov lists 37 US studies indexed under Burns, and 9 of those are currently open to recruitment — roughly 24% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Burns shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Burns is led by Massachusetts General Hospital with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 37 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Burns?
PlainTrial tracks 37 US clinical trials for Burns, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Burns?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.