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ClinicalTrials.gov 9 recruiting now official registry

Burns clinical trials

9 of 37 indexed Burns trials are currently recruiting.

37 US clinical trials · 9 currently recruiting

Burns is the subject of 37 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 5 of these trials.

The research picture

Burns has 37 registered US clinical trials, 9 of them open to new participants right now, about 24% of the total.

9
recruiting participants now
24%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
5
top sponsor: Massachusetts General Hospital
Phase 14Phase 25Phase 34Phase 45

Active & Recent Trials

37 total, page 1 of 1

RECRUITING 400 participants

Understanding the Burn Wound Microbiome: Comparing Traditional Wound Cultures to Next Generation Sequencing Technology

The University of Texas Medical Branch, Galveston

NCT05275335

RECRUITING Phase 2 200 participants

4-Aminopyridine to Treat Skin Burns

John Elfar

NCT06596434

RECRUITING Phase 4 75 participants

Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain

University of Kansas Medical Center

NCT03854344

RECRUITING Phase 4 62 participants

Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft

University of Kansas Medical Center

NCT06379724

RECRUITING Phase 2 60 participants

Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

Skingenix

NCT01297400

RECRUITING NA 30 participants

Impact of a Telerehabilitation Program With Technology Enhancement on Post-burn Recovery

The University of Texas Medical Branch, Galveston

NCT06162052

RECRUITING Phase 4 24 participants

Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers

The Metis Foundation

NCT05217160

RECRUITING NA 21 participants

Suprathel® Use During Prolonged Field Care to Promote Healing and Reduce the Need for Grafting of Burn Wounds

The Metis Foundation

NCT05462860

RECRUITING Phase 4 20 participants

Microsurfaced Grafts in Deep Burn Wounds

CellTherX

NCT04589442

ACTIVE NOT RECRUITING NA 150 participants

Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns

PolyNovo Biomaterials Pty

NCT04090424

ACTIVE NOT RECRUITING NA 66 participants

Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation

Spaulding Rehabilitation Hospital

NCT05351333

COMPLETED 610 participants

Inflammation and the Host Response to Injury (Trauma)

Massachusetts General Hospital

NCT00257231

COMPLETED 280 participants

Inflammation and the Host Response to Injury (Burns)

Massachusetts General Hospital

NCT00257244

COMPLETED 251 participants

DeepView SnapShot Portable (DV-SSP): Device Training Study

SpectralMD

NCT05023135

COMPLETED Phase 2 169 participants

Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)

Cumberland Pharmaceuticals

NCT00061633

COMPLETED NA 101 participants

A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries

Avita Medical

NCT01138917

COMPLETED 100 participants

SSD vs Collagenase in Pediatric Burn Patients

Children's Mercy Hospital Kansas City

NCT00787592

COMPLETED 60 participants

Effect of Burn Size on Cytomegalovirus Reactivation and Correlates of T Cell Immune Function in Burned Patients

University of North Carolina, Chapel Hill

NCT00467532

COMPLETED Phase 2 36 participants

VR for Burn Dressing Changes at Home

Nationwide Children's Hospital

NCT04548635

COMPLETED Phase 1 30 participants

StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns

Stratatech, a Mallinckrodt Company

NCT01437852

COMPLETED Phase 3 27 participants

Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound Dressing

Molnlycke Health Care AB

NCT01214811

COMPLETED NA 26 participants

Virtual Reality in Burn Pain Management

United States Army Institute of Surgical Research

NCT00593086

COMPLETED NA 23 participants

Vashe Wound Therapy Study

Valleywise Health

NCT00586729

COMPLETED Phase 1 20 participants

Patient-Controlled Anxiolysis With Dexmedetomidine (PCA-DEX) for Burn-care Dressing Changes

Ohio State University

NCT02409810

COMPLETED Phase 2 20 participants

Cranial Electrotherapy Stimulation in Burned Patients

United States Army Institute of Surgical Research

NCT00723008

COMPLETED Phase 3 20 participants

Effect of rFVIIa on Peri-operative Blood Loss in Patients Undergoing Major Burn

United States Army Institute of Surgical Research

NCT00243243

COMPLETED NA 19 participants

Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients

Massachusetts General Hospital

NCT01500655

COMPLETED NA 17 participants

Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar

Massachusetts General Hospital

NCT03692273

COMPLETED NA 15 participants

Assessment of Safety and Effectiveness of Biodegradable Temporizing Matrix in the Treatment of Deep Burn Skin Injuries

PolyNovo Biomaterials Pty

NCT02905435

COMPLETED 15 participants

Burn Outcomes in Young Adult Burn Survivors

Massachusetts General Hospital

NCT01254357

COMPLETED NA 14 participants

VR for Pain Management During Adult Burn Dressing Change

Nationwide Children's Hospital

NCT04545229

COMPLETED NA 10 participants

Virtual Reality Hypnosis for Chronic Pain Reduction

University of Washington

NCT01099657

COMPLETED Phase 4 10 participants

Comparison of Wound Bed Establishment in Facial Burns

University of Louisville

NCT01668030

COMPLETED Phase 3 7 participants

Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery

University of Kansas Medical Center

NCT03513406

COMPLETED Early Phase 1 7 participants

Amnion Wound Covering for Enhanced Wound Healing

Wake Forest University Health Sciences

NCT03754218

COMPLETED Phase 1 1 participants

Safety of Extracellular Vesicles for Burn Wounds

Aegle Therapeutics

NCT05078385

COMPLETED Phase 3 1 participants

StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects

Stratatech, a Mallinckrodt Company

NCT05517902

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 5
Phase 3 4
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Burns Trial Landscape

37 indexed Burns studies · 9 recruiting (24%).

Phase mix: 9 late (III/IV) vs 9 early (I/II).

Top sponsor: Massachusetts General Hospital (5 trials), 9 others listed. 37 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Burns?

PlainTrial tracks 37 US clinical trials for Burns, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Burns?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.