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NCT05946798 · ClinicalTrials.gov registry record · Early Phase 1
Role of NADPH Oxidase in Microvascular Dysfunction Following GDM
A Early Phase 1 study of Gestational Diabetes and Oxidative Stress, sponsored by Anna Stanhewicz, PhD.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT05946798: Recruiting Early Phase 1 study of Gestational Diabetes and Oxidative Stress, sponsored by Anna Stanhewicz, PhD.
NCT05946798 is a Early Phase 1 study of Gestational Diabetes and Oxidative Stress that is actively recruiting participants, run by Anna Stanhewicz, PhD. The registered enrollment target is 40 participants, below the 321-participant average among 41 other Gestational Diabetes trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05946798, a Early Phase 1 study of Gestational Diabetes and Oxidative Stress, is actively recruiting participants, sponsored by Anna Stanhewicz, PhD.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this investigation is to examine NADPH oxidase as a source of reactive oxygen species contributing to aberrant microvascular function in otherwise healthy women with a history of GDM.
Primary Outcome
cutaneous vascular vasodilator responses to acetylcholine perfusion in lactated Ringer's, apocynin, L-NAME, and apocynin+L-NAME treated microdialysis sites
Conditions Studied
Interventions
- DRUG Acetylcholine
- DRUG Insulin aspart
Study Locations (1)
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-08-30 |
| Est. Completion | 2028-06-01 |
| Phase | Early Phase 1 |
What NCT05946798 shows while recruiting
NCT05946798 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 321-participant average among 41 other Gestational Diabetes trials with a reported enrollment target (88% lower).
The record links to 3 conditions, with Gestational Diabetes appearing as the primary indexed condition, and to 2 interventions - of which Acetylcholine is the first listed.
NCT05946798 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT05946798 about?
NCT05946798 is a clinical study titled "Role of NADPH Oxidase in Microvascular Dysfunction Following GDM". The purpose of this investigation is to examine NADPH oxidase as a source of reactive oxygen species contributing to aberrant microvascular function in otherwise healthy women with a history of GDM.
What is the current status of trial NCT05946798?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 40 participants. The study started on 2023-08-30. Estimated completion is 2028-06-01.
What conditions does trial NCT05946798 study?
This clinical trial studies the following conditions: Gestational Diabetes, Oxidative Stress, Vascular Endothelial Function.
What interventions are being tested in trial NCT05946798?
The interventions under investigation include: Acetylcholine (DRUG), Insulin aspart (DRUG).
Who is sponsoring clinical trial NCT05946798?
This trial is sponsored by Anna Stanhewicz, PhD, which has 14 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05946798 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gestational Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05946798's enrollment target sits among peer trials
40 28th of 41 higher than 9 of 41 other Gestational Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gestational Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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