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Overweight and Obesity: early-phase trial registry
40 of 116 indexed Overweight and Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #109 of 28,707 conditions by registered trial count.
116 US clinical trials · 40 currently recruiting · #109 of 28,707 conditions by registered trial count
Overweight and Obesity: 116 US clinical trials tracked, 40 recruiting.
Overweight and Obesity is the subject of 116 registered US clinical trials on ClinicalTrials.gov, 40 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 8 of these trials.
Enrollment posture brief
Registry condition overweight-and-obesity
OPEN 40 | RECR 34% | LATE 2 | EARLY 12 | RANK #109 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Colitis, Ulcerative (34% recruiting · 29 trials)
Overweight and Obesity lists 40 open slots (34% of 116 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Overweight and Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Overweight and Obesity is recruiting below its size-band peers.
40 of 116 indexed trials (34.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Overweight and Obesity trials is spread across many organizations.
University of Colorado, Denver accounts for 8 of 116 trials (6.9%). 79 distinct sponsors appear on at least one study for this condition label.
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Typical Overweight and Obesity enrolment sits around 100 participants.
Median target enrolment is 100 among the 116 trials that report a genuine target (sentinel values excluded). 58 of those (50%) plan for fewer than 100 participants.
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Overweight and Obesity research is mostly interventional.
109 interventional and 7 observational studies make up this index (94% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
116 total, page 1 of 3
Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
Memorial Sloan Kettering Cancer Center
NCT05770570
'Ai Pono Cooking Demonstrations
University of Hawaii
NCT06526650
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
Indiana University
NCT05124808
Becoming United in Lifestyle Decisions
University of Connecticut
NCT05796141
Food Prescriptions to Promote Affordable Diets
Kaiser Permanente
NCT05309395
Community Engagement Alliance Against Disparities
Johns Hopkins University
NCT06607341
Optimal Digital Weight Loss Treatment for Rural Individuals
University of South Carolina
NCT06105957
Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention
Seattle Institute for Biomedical and Clinical Research
NCT06390345
Water Intake and Weight Control in Older Adults
Virginia Polytechnic Institute and State University
NCT05843318
Healthy for Two-Home Visiting (H42-HV): Health Coaching for Pregnant Women
Johns Hopkins University
NCT05619705
Social Determinants and a Diabetes Prevention Program Tailored for African Americans
University of Missouri, Kansas City
NCT05301413
Pregnancy Exercise Mode Effect on Childhood Obesity
East Carolina University
NCT04805502
Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
University of Colorado, Denver
NCT05107908
PILI 'Āina Household
University of Hawaii
NCT06526273
Control Systems Engineering for Weight Loss Maintenance
The Miriam Hospital
NCT06244888
Early vs. Late Time Restricted Eating vs. Daily Caloric Restriction
University of Colorado, Denver
NCT05870982
Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes
University of Colorado, Denver
NCT04791371
An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents
Drexel University
NCT06147973
Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0
Penn State University
NCT05807594
Timing Intervention of Morning Versus Evening Exercise
University of Colorado, Denver
NCT05153252
Lifestyle Intervention for Healthy Change
Augusta University
NCT05956574
Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities
University of Kansas Medical Center
NCT06961591
Metformin IN Asthma for Overweight and Obese Individuals (MINA)
Johns Hopkins University
NCT06273072
Cottonseed Oil Versus Matched PUFA Effects
University of Georgia
NCT06382298
Dose Response Effects of Pecan Consumption
University of Georgia
NCT05949879
Breathing & Blood Pressure
Florida State University
NCT05632406
Cottonseed Oil Dose Response
University of Georgia
NCT05686954
Effects of Watermelon or Low-fat Cookie Consumption on Wellness
San Diego State University
NCT06323070
Intermittent Cottonseed Oil Consumption
University of Georgia
NCT07246408
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
University of Virginia
NCT06009276
Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
University of Utah
NCT06180837
Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
Stanford University
NCT05912621
A Pilot Factorial Trial of an Integrated Lifestyle Intervention
University of Colorado, Denver
NCT06116435
Time-restricted Eating for Postpartum Weight Loss
University of Alabama at Birmingham
NCT06491537
Testing the Adipose Expandability Hypothesis in Vivo During Overfeeding
Pennington Biomedical Research Center
NCT04583514
Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes
Pennington Biomedical Research Center
NCT05958368
Human Models of Selective Insulin Resistance: Alpelisib, Part I
Columbia University
NCT06354088
Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity
San Diego State University
NCT05726942
Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment
Brigham and Women's Hospital
NCT06069622
Circadian Intervention to Improve Cardiometabolic Health
University of Utah
NCT05943626
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
Johns Hopkins University
NCT06347484
Biological Sample Repository for Gastrointestinal Disorders
Pichamol Jirapinyo, MD, MPH
NCT05874726
Project Health: Enhancing Effectiveness of a Dissonance-Based Obesity Prevention Program
Oregon Research Institute
NCT03710746
Using Signos mHealth Platform in Adults for Weight Management
Signos
NCT06214221
A Trial to Compare the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administered Using Two Subcutaneous Presentations
Amgen
NCT07313761
Solutions for Hunger and Regulating Eating
University of California, San Diego
NCT05004883
Stepping Into Lifestyle Changes
University of Alabama at Birmingham
NCT05625321
Choosing Healthy Activities and Lifestyle Management Through Portal Support
University of Tennessee
NCT05410353
Enhancing BodyWorks: a Canine Health Literacy Module
Children's Hospital Los Angeles
NCT04516252
Healthy Living After Knee Replacement
University of South Carolina
NCT05190666
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 8 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Overweight and Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Overweight and Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Overweight and Obesity page
116 registered trials, 40 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 40 Overweight and Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Colorado, Denver sponsors the most Overweight and Obesity trials on record, review their full trial history before evaluating a specific study. See University of Colorado, Denver's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Overweight and Obesity condition card totals 116 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.