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Water Intake and Weight Control in Older Adults
NCT05843318 · View on ClinicalTrials.gov ↗
Study Summary
This study is a randomized controlled intervention trial in adults aged 50+ years with overweight or obesity, which will compare three groups with different diet prescriptions: 1) pre-meal water consumption (500 ml, before each main meal) with a hypocaloric diet; 2) 1500 ml water consumed throughout the day with a hypocaloric diet; 3) hypocaloric diet with no instructions regarding water consumption. Smart water bottles will objectively assess water intake timing and volume. Urine osmolality, urine volume, and serum osmolality will be used as objective indicators of compliance with the water intake prescription. We will investigate changes in perceived hunger and fullness and appetite-regulating hormones as potential mechanisms by which premeal water could improve appetite regulation. We will also investigate the impact of water consumption and hydration on executive function capabilities, which may influence intervention adherence. Although increasing water intake could be an effective weight management strategy, no evidence-based recommendations exist for the timing of water intake needed for this benefit.
Conditions Studied
Interventions
- BEHAVIORAL Water intake and weight control in older adults - Premeal Water + hypocaloric diet
- BEHAVIORAL Water intake and weight control in older adults - Total Daily Water + hypocaloric diet
- BEHAVIORAL Water Intake and weight control in older adults - hypocaloric diet alone
Study Locations (1)
Virginia
- Virginia Tech — Blacksburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 375 participants |
| Start Date | 2023-11-13 |
| Est. Completion | 2028-03-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05843318
The ClinicalTrials.gov registry entry for NCT05843318 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 375 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Polytechnic Institute and State University, which has 93 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Overweight and Obesity appearing as the primary indexed condition, and to 3 interventions — of which Water intake and weight control in older adults - Premeal Water + hypocaloric diet is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05843318 reports 1 study location spanning 1 distinct geographic area — top geographies include Virginia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05843318 about?
NCT05843318 is a clinical study titled "Water Intake and Weight Control in Older Adults". This study is a randomized controlled intervention trial in adults aged 50+ years with overweight or obesity, which will compare three groups with different diet prescriptions: 1) pre-meal water consumption (500 ml, before each main meal) with a hypocaloric diet; 2) 1500 ml water consumed throughout...
What is the current status of trial NCT05843318?
This trial is currently recruiting. It is a NA study. The enrollment target is 375 participants. The study started on 2023-11-13. Estimated completion is 2028-03-31.
What conditions does trial NCT05843318 study?
This clinical trial studies the following conditions: Overweight and Obesity. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05843318?
The interventions under investigation include: Water intake and weight control in older adults - Premeal Water + hypocaloric diet (BEHAVIORAL), Water intake and weight control in older adults - Total Daily Water + hypocaloric diet (BEHAVIORAL), Water Intake and weight control in older adults - hypocaloric diet alone (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05843318?
This trial is sponsored by Virginia Polytechnic Institute and State University, which has 93 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05843318 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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