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NCT06009276 · ClinicalTrials.gov registry record
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
A clinical trial of Overweight and Obesity and Peripheral Arterial Disease, sponsored by University of Virginia.
- Recruiting
- Registry status
- 70
- Enrollment target
- 1
- Study location
NCT06009276: Recruiting study of Overweight and Obesity and Peripheral Arterial Disease, sponsored by University of Virginia.
NCT06009276 is a study of Overweight and Obesity and Peripheral Arterial Disease that is actively recruiting participants, run by University of Virginia. The registered enrollment target is 70 participants, below the 228-participant average among 115 other Overweight and Obesity trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06009276, a study of Overweight and Obesity and Peripheral Arterial Disease, is actively recruiting participants, sponsored by University of Virginia.
- RECRUITING
- Registry status
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to determine associations between fitness status, bacteria in the mouth, and the blood flow to muscle. This study is trying to find out if fitness status impacts the bacteria that are present in the oral microbiome (environment in the mouth) or the ability of the body to send blood to the skeletal muscle. Participants will complete all or some of the following: * A mouth swab to assess the bacteria in their mouths. * Produce a saliva sample into a tube. * Cycle on a bike until you reach maximum effort. * Undergo blood draws * Wear a 24-hour non-invasive device that monitors blood pressure. * Drink 70mL (1/3 of a cup) of concentrated beetroot juice once
Primary Outcome
Assessment of the oral microbiome's ability to reduce nitrate to nitrite. This will be measured through a swab on the dorsal surface of the tongue, an unstimulated saliva sample, and a rinse of a standard nitrate solution.
Conditions Studied
Study Locations (1)
Virginia
- UVA Student Health and Wellness Building - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2023-08-30 |
| Est. Completion | 2026-12 |
What NCT06009276 shows while recruiting
NCT06009276 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 228-participant average among 115 other Overweight and Obesity trials with a reported enrollment target (69% lower).
The record links to 4 conditions, with Overweight and Obesity appearing as the primary indexed condition, and to 0 interventions.
NCT06009276 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT06009276 about?
NCT06009276 is a clinical study titled "Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status". The purpose of the study is to determine associations between fitness status, bacteria in the mouth, and the blood flow to muscle. This study is trying to find out if fitness status impacts the bacteria that are present in the oral microbiome (environment in the mouth) or the ability of the body to ...
What is the current status of trial NCT06009276?
This trial is currently recruiting. The enrollment target is 70 participants. The study started on 2023-08-30. Estimated completion is 2026-12.
What conditions does trial NCT06009276 study?
This clinical trial studies the following conditions: Overweight and Obesity, Peripheral Arterial Disease, Heart Failure, Diastolic, Heart Failure, Systolic.
Who is sponsoring clinical trial NCT06009276?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06009276 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06009276's enrollment target sits among peer trials
70 70th of 115 higher than 44 of 115 other Overweight and Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Overweight and Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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