Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Orthostatic Hypotension: early-phase trial registry
8 of 17 indexed Orthostatic Hypotension trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,004 of 28,707 conditions by registered trial count.
17 US clinical trials · 8 currently recruiting · #1,004 of 28,707 conditions by registered trial count
Orthostatic Hypotension: 17 US clinical trials tracked, 8 recruiting.
Orthostatic Hypotension is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 3 of these trials.
Enrollment posture brief
Registry condition orthostatic-hypotension
OPEN 8 | RECR 47% | LATE 0 | EARLY 6 | RANK #1004 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Bone Loss (47% recruiting · 17 trials)
Orthostatic Hypotension lists 8 open slots (47% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Orthostatic Hypotension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Orthostatic Hypotension recruits in line with its size-band peers.
8 of 17 indexed trials (47.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates Orthostatic Hypotension research.
Vanderbilt University Medical Center accounts for 3 of 17 trials (17.6%). 12 distinct sponsors appear on at least one study for this condition label.
-
Most Orthostatic Hypotension trials plan to enrol fewer than 100 people.
Median target enrolment is 31 among the 17 trials that report a genuine target (sentinel values excluded). 16 of those (94.1%) plan for fewer than 100 participants.
-
Orthostatic Hypotension research is mostly interventional.
16 interventional and 1 observational studies make up this index (94.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
17 total, page 1 of 1
Deciphering Preserved Autonomic Function After Spinal Cord Injury
Mayo Clinic
NCT04493372
Blood Pressure Effects on Cognition and Brain Blood Flow in PD
University of California, San Diego
NCT05400174
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure
Vanderbilt University Medical Center
NCT02897063
Automated Abdominal Binder for Orthostatic Hypotension
Vanderbilt University Medical Center
NCT03482297
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
Vanderbilt University Medical Center
NCT02429557
Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury
James J. Peters Veterans Affairs Medical Center
NCT05960448
Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)
Kessler Foundation
NCT05731986
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
Kessler Foundation
NCT05725499
Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI
Methodist Rehabilitation Center
NCT04029974
Water and the Gastropressor Response - Diurnal Variability
Satish R. Raj
NCT00581373
Water and the Gastropressor Response - Tachyphylaxis
Satish R. Raj
NCT00580996
Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic
Vanderbilt University
NCT02726711
Orthostatic Hypotension Treatment on Rehab Unit
VA Office of Research and Development
NCT01030874
Data Collection - Of Syncope Tilt Table Testing Study
Boston Scientific Corporation
NCT03721393
The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Brigham and Women's Hospital
NCT03674541
Safety and Efficacy of L-NAME and Midodrine to Increase MAP
US Department of Veterans Affairs
NCT00835224
Abdominal Compression in Orthostatic Hypotension
Mayo Clinic
NCT01223391
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Orthostatic Hypotension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Orthostatic Hypotension trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Orthostatic Hypotension page
17 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Orthostatic Hypotension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Vanderbilt University Medical Center sponsors the most Orthostatic Hypotension trials on record, review their full trial history before evaluating a specific study. See Vanderbilt University Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Orthostatic Hypotension condition card totals 17 registered trials; most-linked intervention Placebo; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.