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ClinicalTrials.gov 8 recruiting now full pipeline small index

Bone Loss: full-pipeline trial registry

8 of 17 indexed Bone Loss trials are currently recruiting.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 8 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Bone Loss: 17 US clinical trials tracked, 8 recruiting.

Bone Loss is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 2 of these trials.

Enrollment posture brief

Registry condition bone-loss

OPEN 8 | RECR 47% | LATE 4 | EARLY 4 | RANK #1004 | SPON 2

Nearest open-share peer: Disability Physical (47% recruiting · 17 trials)

Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Bone Loss (this)47%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Bone Loss

Bone Loss lists 8 open slots (47% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Bone Loss on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Bone Loss recruits in line with its size-band peers.

    8 of 17 indexed trials (47.1%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Bone Loss trials is spread across many organizations.

    Northwestern University accounts for 2 of 17 trials (11.8%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Most Bone Loss trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 17 trials that report a genuine target (sentinel values excluded). 12 of those (70.6%) plan for fewer than 100 participants.

  4. Bone Loss research is mostly interventional.

    12 interventional and 5 observational studies make up this index (70.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 24Phase 31Phase 43

Open and recent trials

17 total, page 1 of 1

RECRUITING Phase 4 1,710 participants

LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women

Insud Pharma

NCT05303636

RECRUITING Phase 4 900 participants

Bone, Exercise, Alendronate, and Caloric Restriction

Wake Forest University Health Sciences

NCT05764733

RECRUITING 600 participants

An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects

AO Innovation Translation Center

NCT04112992

RECRUITING Phase 3 200 participants

Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery

Wake Forest University Health Sciences

NCT04922333

RECRUITING Phase 2 103 participants

Bone in CKD Alkali Response (BICARb Pilot Trial)

Albert Einstein College of Medicine

NCT05918029

RECRUITING 80 participants

Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk

Creighton University

NCT05701254

RECRUITING NA 80 participants

Lutein, Zeaxathin, and Fish Oil Supplementation

Texas A&M University

NCT06489873

RECRUITING NA 44 participants

Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor

University of Alabama at Birmingham

NCT04954664

ACTIVE NOT RECRUITING 63 participants

CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis

Indiana University

NCT04206436

ACTIVE NOT RECRUITING NA 48 participants

TRE: Microbiome, Metabolic Health and Bone

Rutgers, The State University of New Jersey

NCT05548517

ACTIVE NOT RECRUITING 5 participants

Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis

University of Alabama at Birmingham

NCT04964466

COMPLETED Phase 2 60 participants

Prevention of Bone Loss After Acute SCI by Zoledronic Acid

Northwestern University

NCT02325414

COMPLETED Phase 2 60 participants

Zoledronic Acid to Prevent Bone Loss During Androgen Deprivation Therapy for Prostate Cancer

Massachusetts General Hospital

NCT00181584

COMPLETED NA 42 participants

Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency

United States Army Research Institute of Environmental Medicine

NCT01292395

COMPLETED 40 participants

Bone Loss After Laparoscopic Roux-en-Y Gastric Bypass

Gundersen Lutheran Medical Foundation

NCT00975013

COMPLETED Phase 2 25 participants

12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)

Northwestern University

NCT02025179

COMPLETED Phase 4 12 participants

Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI)

Thomas J. Schnitzer

NCT00826228

Phase Distribution

PhaseTrial count
Phase 2 4
Phase 3 1
Phase 4 3

Named interventions

Most-linked intervention names on Bone Loss records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Other
3 trials
Zoledronic acid Drug
2 trials
Placebo Drug
2 trials
weight-bearing Other
1 trials
Dietary Protein Intake Other
1 trials
teriparatide Drug
1 trials
Time Restricted Eating (TRE) Behavioral
1 trials
Release kinetics of PDGF-BB in rhPDGF-BB + PRF + bone substitutes Biological
1 trials

US sites by state

Facility locations filed on Bone Loss trials. A trial with sites in several states counts in each.

North Carolina 3 trials
Illinois 3 trials
Texas 2 trials
Nebraska 2 trials
North Dakota 2 trials
Colorado 2 trials
Alabama 2 trials
Wisconsin 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Bone Loss page

17 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Bone Loss condition card totals 17 registered trials; most-linked intervention Placebo; top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.