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Bone Loss clinical trials
8 of 17 indexed Bone Loss trials are currently recruiting.
17 US clinical trials · 8 currently recruiting
Bone Loss is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 2 of these trials.
The research picture
Bone Loss has 17 registered US clinical trials, 8 of them open to new participants right now, about 47% of the total.
- 8
- recruiting participants now
- 47%
- of trials open to enrollment
- 4
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Northwestern University
Active & Recent Trials
17 total, page 1 of 1
LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
Insud Pharma
NCT05303636
Bone, Exercise, Alendronate, and Caloric Restriction
Wake Forest University Health Sciences
NCT05764733
An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects
AO Innovation Translation Center
NCT04112992
Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery
Wake Forest University Health Sciences
NCT04922333
Bone in CKD Alkali Response (BICARb Pilot Trial)
Albert Einstein College of Medicine
NCT05918029
Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk
Creighton University
NCT05701254
Lutein, Zeaxathin, and Fish Oil Supplementation
Texas A&M University
NCT06489873
Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
University of Alabama at Birmingham
NCT04954664
CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis
Indiana University
NCT04206436
TRE: Microbiome, Metabolic Health and Bone
Rutgers, The State University of New Jersey
NCT05548517
Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis
University of Alabama at Birmingham
NCT04964466
Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Northwestern University
NCT02325414
Zoledronic Acid to Prevent Bone Loss During Androgen Deprivation Therapy for Prostate Cancer
Massachusetts General Hospital
NCT00181584
Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency
United States Army Research Institute of Environmental Medicine
NCT01292395
Bone Loss After Laparoscopic Roux-en-Y Gastric Bypass
Gundersen Lutheran Medical Foundation
NCT00975013
12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)
Northwestern University
NCT02025179
Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI)
Thomas J. Schnitzer
NCT00826228
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 4 |
| Phase 3 | 1 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Bone Loss Trial Landscape
17 indexed Bone Loss studies · 8 recruiting (47%).
Phase mix: 4 late (III/IV) vs 4 early (I/II).
Top sponsor: Northwestern University (2 trials), 9 others listed. 17 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Bone Loss?
PlainTrial tracks 17 US clinical trials for Bone Loss, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Bone Loss?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.