Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02897063 · ClinicalTrials.gov registry record · Phase 1

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

A Phase 1 study of Parkinson Disease and Multiple System Atrophy, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
Phase 1
Development phase
34
Enrollment target
1
Study location

NCT02897063 is a Phase 1 study of Parkinson Disease and Multiple System Atrophy that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 34 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02897063, a Phase 1 study of Parkinson Disease and Multiple System Atrophy, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
Phase 1
Development phase
34 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low blood pressure on standing), on the veins of the abdomen of patients with autonomic failure. The study will be conducted at Vanderbilt University Medical Center, and consists of 2 parts: a screening and 2 testing days. The total length of the study will be about 5 days. About 34 participants will be screened for the study.

Interventions

  • DRUG Placebo
  • DRUG Midodrine
  • DRUG Droxidopa

Study Locations (1)

Tennessee

  • Autonomic Dysfunction Center/ Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 34 participants
Start Date 2016-09
Est. Completion 2026-12
Phase Phase 1

What the Registry Record Tells You About NCT02897063

The ClinicalTrials.gov registry entry for NCT02897063 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT02897063 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT02897063 about?

NCT02897063 is a clinical study titled "Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure". The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low blood pressure on standing), on the veins of the abdomen of patients with autonomic failure. The study will be conducted at Vanderbilt Unive...

What is the current status of trial NCT02897063?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2016-09. Estimated completion is 2026-12.

What conditions does trial NCT02897063 study?

This clinical trial studies the following conditions: Parkinson Disease, Multiple System Atrophy, Orthostatic Hypotension, Autonomic Failure, Pure Autonomic Failure.

What interventions are being tested in trial NCT02897063?

The interventions under investigation include: Placebo (DRUG), Midodrine (DRUG), Droxidopa (DRUG).

Who is sponsoring clinical trial NCT02897063?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02897063 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Parkinson Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.