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NCT02726711 · ClinicalTrials.gov registry record · Phase 1
Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic
A Phase 1 study of Multiple System Atrophy and Orthostatic Hypotension, sponsored by Vanderbilt University.
- Active
- Registry status
- Phase 1
- Development phase
- 2
- Enrollment target
- 1
- Study location
NCT02726711 is a Phase 1 study of Multiple System Atrophy and Orthostatic Hypotension that is active but no longer recruiting, run by Vanderbilt University. The registered enrollment target is 2 participants, below the 268-participant average among 30 other Multiple System Atrophy trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02726711, a Phase 1 study of Multiple System Atrophy and Orthostatic Hypotension, is active but no longer recruiting, sponsored by Vanderbilt University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 2 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to learn more about the regulation of the veins of the abdomen by the autonomic (involuntary) nervous system, and how this may affect high blood pressure. Normally, the autonomic nervous system controls how much blood flows in the veins. In people with high blood pressure, however, the autonomic nervous system is changed. This change may affect the way blood flows in the veins of the abdomen which may play a role in their high blood pressure. About 32 participants will be screened for the study. The investigators estimate 16 will be eligible to participate in all of the study days.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Trimethaphan
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2016-04 |
| Est. Completion | 2026-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02726711
The ClinicalTrials.gov registry entry for NCT02726711 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 268-participant average among 30 other Multiple System Atrophy trials with a reported enrollment target (99% lower). The listed sponsor is Vanderbilt University, which has 430 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Multiple System Atrophy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02726711 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT02726711 about?
NCT02726711 is a clinical study titled "Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic". The purpose of this study is to learn more about the regulation of the veins of the abdomen by the autonomic (involuntary) nervous system, and how this may affect high blood pressure. Normally, the autonomic nervous system controls how much blood flows in the veins. In people with high blood pressur...
What is the current status of trial NCT02726711?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 2 participants. The study started on 2016-04. Estimated completion is 2026-12.
What conditions does trial NCT02726711 study?
This clinical trial studies the following conditions: Multiple System Atrophy, Orthostatic Hypotension, Supine Hypertension.
What interventions are being tested in trial NCT02726711?
The interventions under investigation include: Placebo (DRUG), Trimethaphan (DRUG).
Who is sponsoring clinical trial NCT02726711?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02726711 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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