Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obesity and Overweight
Open-data reference.
28 US clinical trials · 27 currently recruiting
Active & Recent Trials
Advancing Biopsychosocial Care Training Initiative
Washington University School of Medicine
NCT07049861
Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity
Metsera, a wholly owned subsidiary of Pfizer
NCT07311850
CHIME: Comparing Health Interventions for Maternal Equity
Stanford University
NCT06724172
Comparision of Aerobic Exercise to Aerobic Plus Yoga Exercise for Weight Loss in Adults With Overweight or Obesity.
University of Kansas Medical Center
NCT06636773
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
University of North Carolina, Chapel Hill
NCT06724406
Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
Johns Hopkins University
NCT06861868
A Mobile Intervention to Reduce Pain and Improve Health-III
Wake Forest University
NCT06623669
A Phase 1 Study of WVE-007 in Adults Living With Overweight or Obesity
Wave Life Sciences
NCT06842186
Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder
Johns Hopkins University
NCT06847399
Study of Patients Being Treated With Anti-obesity Medication
Texas Tech University
NCT06790160
A Study to Evaluate a Postbiotic in Supporting Weight Loss and Metabolic Health
ResBiotic Nutrition
NCT06911073
Weight Management Intervention in College: A Pilot
The Miriam Hospital
NCT06994923
New Mechanisms of Obesity
Yale University
NCT06768827
To Test Whether Time-restricted Eating Coupled With a Healthy Diet is Beneficial in Liver Cancer Patients
University of California, San Diego
NCT06824974
Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
John Bauer
NCT06967389
FRESH-EATS Project
University of South Florida
NCT07053644
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Rutgers, The State University of New Jersey
NCT06949280
Tirzepatide for Alcohol Use Disorder
University of Southern California
NCT06994338
Muscle and Movement With Anti-Obesity Medications
University of Kansas Medical Center
NCT06645470
BrainWeighve App Feasibility Study
University of California, Los Angeles
NCT05530538
Effect of Watermelon on Gut and Cardiometabolic Health
Florida State University
NCT06588218
Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial
University of Alabama at Birmingham
NCT06976307
Metabotyping of Broccoli Microgreen in Obese Breast Cancer Survivors
University of Maryland, Baltimore
NCT07032545
MAINTAIN (Mucosal AblatIoN Therapy After INcretins)
Dr. Christopher McGowan
NCT06734312
Effects of Ultra Processed Food on Intestinal Energy Harvest
Columbia University
NCT06853288
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
University of Hawaii
NCT06935838
REvision of VSG with Ablation of the Mucosa Procedure
Dr. Christopher McGowan
NCT06671119
A Study of MET233 in Individuals With Obesity or Overweight
Metsera, a wholly owned subsidiary of Pfizer
NCT07022977
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Obesity and Overweight Trial Landscape
ClinicalTrials.gov lists 28 US studies indexed under Obesity and Overweight, and 27 of those are currently open to recruitment — roughly 96% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Obesity and Overweight shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Obesity and Overweight is led by Dr. Christopher McGowan with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Obesity and Overweight?
PlainTrial tracks 28 US clinical trials for Obesity and Overweight, of which 27 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Obesity and Overweight?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.