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Obesity and Overweight: early-phase trial registry
27 of 28 indexed Obesity and Overweight trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #577 of 28,707 conditions by registered trial count.
28 US clinical trials · 27 currently recruiting · #577 of 28,707 conditions by registered trial count
Obesity and Overweight: 28 US clinical trials tracked, 27 recruiting.
Obesity and Overweight is the subject of 28 registered US clinical trials on ClinicalTrials.gov, 27 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Dr. Christopher McGowan, running 2 of these trials.
Enrollment posture brief
Registry condition obesity-and-overweight
OPEN 27 | RECR 96% | LATE 1 | EARLY 6 | RANK #577 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Depression - Major Depressive Disorder (95% recruiting · 20 trials)
Obesity and Overweight lists 27 open slots (96% of 28 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity and Overweight on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obesity and Overweight is recruiting above its size-band peers.
27 of 28 indexed trials (96.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity and Overweight trials is spread across many organizations.
Dr. Christopher McGowan accounts for 2 of 28 trials (7.1%). 24 distinct sponsors appear on at least one study for this condition label.
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Most Obesity and Overweight trials plan to enrol fewer than 100 people.
Median target enrolment is 55 among the 28 trials that report a genuine target (sentinel values excluded). 17 of those (60.7%) plan for fewer than 100 participants.
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Obesity and Overweight research is mostly interventional.
25 interventional and 3 observational studies make up this index (89.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
28 total, page 1 of 1
Advancing Biopsychosocial Care Training Initiative
Washington University School of Medicine
NCT07049861
Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity
Metsera, a wholly owned subsidiary of Pfizer
NCT07311850
CHIME: Comparing Health Interventions for Maternal Equity
Stanford University
NCT06724172
Comparision of Aerobic Exercise to Aerobic Plus Yoga Exercise for Weight Loss in Adults With Overweight or Obesity.
University of Kansas Medical Center
NCT06636773
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
University of North Carolina, Chapel Hill
NCT06724406
Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
Johns Hopkins University
NCT06861868
A Mobile Intervention to Reduce Pain and Improve Health-III
Wake Forest University
NCT06623669
A Phase 1 Study of WVE-007 in Adults Living With Overweight or Obesity
Wave Life Sciences
NCT06842186
Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder
Johns Hopkins University
NCT06847399
Study of Patients Being Treated With Anti-obesity Medication
Texas Tech University
NCT06790160
A Study to Evaluate a Postbiotic in Supporting Weight Loss and Metabolic Health
ResBiotic Nutrition
NCT06911073
Weight Management Intervention in College: A Pilot
The Miriam Hospital
NCT06994923
New Mechanisms of Obesity
Yale University
NCT06768827
To Test Whether Time-restricted Eating Coupled With a Healthy Diet is Beneficial in Liver Cancer Patients
University of California, San Diego
NCT06824974
Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
John Bauer
NCT06967389
FRESH-EATS Project
University of South Florida
NCT07053644
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Rutgers, The State University of New Jersey
NCT06949280
Tirzepatide for Alcohol Use Disorder
University of Southern California
NCT06994338
Muscle and Movement With Anti-Obesity Medications
University of Kansas Medical Center
NCT06645470
BrainWeighve App Feasibility Study
University of California, Los Angeles
NCT05530538
Effect of Watermelon on Gut and Cardiometabolic Health
Florida State University
NCT06588218
Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial
University of Alabama at Birmingham
NCT06976307
Metabotyping of Broccoli Microgreen in Obese Breast Cancer Survivors
University of Maryland, Baltimore
NCT07032545
MAINTAIN (Mucosal AblatIoN Therapy After INcretins)
Dr. Christopher McGowan
NCT06734312
Effects of Ultra Processed Food on Intestinal Energy Harvest
Columbia University
NCT06853288
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
University of Hawaii
NCT06935838
REvision of VSG with Ablation of the Mucosa Procedure
Dr. Christopher McGowan
NCT06671119
A Study of MET233 in Individuals With Obesity or Overweight
Metsera, a wholly owned subsidiary of Pfizer
NCT07022977
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity and Overweight records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity and Overweight trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity and Overweight page
28 registered trials, 27 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 27 Obesity and Overweight trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Dr. Christopher McGowan sponsors the most Obesity and Overweight trials on record, review their full trial history before evaluating a specific study. See Dr. Christopher McGowan's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity and Overweight condition card totals 28 registered trials; most-linked intervention Tirzepatide; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.