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NCT06842186 · ClinicalTrials.gov registry record · Phase 1

A Phase 1 Study of WVE-007 in Adults Living With Overweight or Obesity

A Phase 1 study of Obesity and Overweight, sponsored by Wave Life Sciences.

Recruiting
Registry status
Phase 1
Development phase
136
Enrollment target
6
Study locations

NCT06842186 is a Phase 1 study of Obesity and Overweight that is actively recruiting participants, run by Wave Life Sciences. The registered enrollment target is 136 participants, below the 460-participant average among 27 other Obesity and Overweight trials with a reported enrollment target (70% lower). The trial reports 6 study locations across 2 states.

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The verdict

NCT06842186, a Phase 1 study of Obesity and Overweight, is actively recruiting participants, sponsored by Wave Life Sciences.

RECRUITING
Registry status
Phase 1
Development phase
136 participants
Enrollment target
6
Study locations

Study Summary

The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of WVE-007 when administered subcutaneously (SC) as single ascending doses in adults who are affected by overweight or obesity.

Conditions Studied

Obesity and Overweight

Interventions

  • DRUG WVE-007

Study Locations (6)

Other

  • ARENSIA Research Clinic - Chisinau
  • Arensia Clinics S.R.L. - Bucharest
  • Spitalul Clinic Judetean De Urgenta Cluj - Cluj-Napoca
  • Parexel International Early Phase Clinical Unit - Harrow
  • Simbec-Orion Clinical Pharmacology - Merthyr Tydfil

Maryland

  • Parexel International-EPCU Baltimore - Baltimore

Trial Details

FieldValue
Enrollment Target 136 participants
Start Date 2025-01-31
Est. Completion 2026-10
Phase Phase 1

Sponsor

Wave Life Sciences

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06842186

The ClinicalTrials.gov registry entry for NCT06842186 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 136 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 460-participant average among 27 other Obesity and Overweight trials with a reported enrollment target (70% lower). The listed sponsor is Wave Life Sciences, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Obesity and Overweight appearing as the primary indexed condition, and to 1 intervention - of which WVE-007 is the first listed.

NCT06842186 reports 6 study locations spanning 2 distinct geographic areas - top geographies include Other, Maryland.

Frequently Asked Questions

What is clinical trial NCT06842186 about?

NCT06842186 is a clinical study titled "A Phase 1 Study of WVE-007 in Adults Living With Overweight or Obesity". The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of WVE-007 when administered subcutaneously (SC) as single ascending doses in adults who are affected by overweight or obesity.

What is the current status of trial NCT06842186?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 136 participants. The study started on 2025-01-31. Estimated completion is 2026-10.

What conditions does trial NCT06842186 study?

This clinical trial studies the following conditions: Obesity and Overweight.

What interventions are being tested in trial NCT06842186?

The interventions under investigation include: WVE-007 (DRUG).

Who is sponsoring clinical trial NCT06842186?

This trial is sponsored by Wave Life Sciences, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06842186 being conducted?

This trial has 6 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.