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RECRUITING Phase 3

Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity

NCT07311850 · View on ClinicalTrials.gov ↗

Study Summary

This study investigates the efficacy and safety of once weekly injectable MET097 in adult participants with obesity or overweight with weight-related comorbidities excluding T2D. This trial will last for a duration of 84 weeks. The primary endpoint will be assessed after 64 weeks of treatment with the secondary at 84 weeks.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG MET097

Study Locations (5)

California

  • Research Site 97301-001007 — Riverside
  • Research Site 97301-001070 — Torrance

Colorado

  • Research Site 97301-001077 — Englewood

Florida

  • Research Site 97302-001001 — Hollywood

North Carolina

  • Research Site 97301-001309 — Cary

Trial Details

FieldValue
Enrollment Target 3,500 participants
Start Date 2025-12-29
Est. Completion 2028-05
Phase Phase 3

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07311850

The ClinicalTrials.gov registry entry for NCT07311850 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Metsera, a wholly owned subsidiary of Pfizer, which has 6 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Obesity and Overweight appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07311850 reports 5 study locations spanning 4 distinct geographic areas — top geographies include California, Colorado, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07311850 about?

NCT07311850 is a clinical study titled "Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity". This study investigates the efficacy and safety of once weekly injectable MET097 in adult participants with obesity or overweight with weight-related comorbidities excluding T2D. This trial will last for a duration of 84 weeks. The primary endpoint will be assessed after 64 weeks of treatment with t...

What is the current status of trial NCT07311850?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 3,500 participants. The study started on 2025-12-29. Estimated completion is 2028-05.

What conditions does trial NCT07311850 study?

This clinical trial studies the following conditions: Obesity and Overweight. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07311850?

The interventions under investigation include: Placebo (DRUG), MET097 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07311850?

This trial is sponsored by Metsera, a wholly owned subsidiary of Pfizer, which has 6 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07311850 being conducted?

This trial has 5 study locations across California, Colorado, Florida, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial