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NCT06994338 · ClinicalTrials.gov registry record · Phase 2

Tirzepatide for Alcohol Use Disorder

A Phase 2 study of Alcohol Use Disorder and Obesity and Overweight, sponsored by University of Southern California.

Recruiting
Registry status
Phase 2
Development phase
42
Enrollment target
1
Study location

NCT06994338 is a Phase 2 study of Alcohol Use Disorder and Obesity and Overweight that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 42 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06994338, a Phase 2 study of Alcohol Use Disorder and Obesity and Overweight, is actively recruiting participants, sponsored by University of Southern California.

RECRUITING
Registry status
Phase 2
Development phase
42 participants
Enrollment target
1
Study location

Study Summary

The objective of this Phase 2 randomized controlled trial is to evaluate the effects of weekly tirzepatide (vs. placebo) on alcohol consumption and cardiometabolic outcomes in adults with alcohol use disorder and overweight or obesity.

Conditions Studied

Alcohol Use Disorder Obesity and Overweight Alcohol

Interventions

  • DRUG Tirzepatide
  • DRUG Placebo injections

Study Locations (1)

California

  • Keck School of Medicine, University of Southern California - Los Angeles

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2025-10-06
Est. Completion 2026-08-31
Phase Phase 2

Sponsor

University of Southern California

617 total trials

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What the Registry Record Tells You About NCT06994338

The ClinicalTrials.gov registry entry for NCT06994338 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (87% lower). The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Tirzepatide is the first listed.

NCT06994338 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06994338 about?

NCT06994338 is a clinical study titled "Tirzepatide for Alcohol Use Disorder". The objective of this Phase 2 randomized controlled trial is to evaluate the effects of weekly tirzepatide (vs. placebo) on alcohol consumption and cardiometabolic outcomes in adults with alcohol use disorder and overweight or obesity.

What is the current status of trial NCT06994338?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2025-10-06. Estimated completion is 2026-08-31.

What conditions does trial NCT06994338 study?

This clinical trial studies the following conditions: Alcohol Use Disorder, Obesity and Overweight, Alcohol.

What interventions are being tested in trial NCT06994338?

The interventions under investigation include: Tirzepatide (DRUG), Placebo injections (DRUG).

Who is sponsoring clinical trial NCT06994338?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06994338 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.