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2026 data Public-data reference. official source

Nonalcoholic Steatohepatitis

Open-data reference.

18 US clinical trials · 6 currently recruiting

Active & Recent Trials

RECRUITING 15,000 participants

A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)

Target PharmaSolutions

NCT02815891

RECRUITING 240 participants

Predicting Outcomes in Nonalcoholic Steatohepatitis With Advanced Fibrosis

Virginia Commonwealth University

NCT05720663

RECRUITING Phase 2 166 participants

Low-Dose Pioglitazone in Patients With NASH (AIM 2)

University of Florida

NCT04501406

RECRUITING Phase 2 128 participants

Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans

VA Office of Research and Development

NCT05526144

RECRUITING NA 110 participants

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

Stanford University

NCT05165706

RECRUITING NA 100 participants

Metabolic Pathology of Pediatric NAFLD

University of Oklahoma

NCT05430178

ACTIVE NOT RECRUITING 533 participants

Prevalence of NAFLD and Advanced Fibrosis in Patients With Type 1 Diabetes

Joslin Diabetes Center

NCT04595474

ACTIVE NOT RECRUITING Phase 2 219 participants

Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis

Rivus Pharmaceuticals

NCT05979779

ACTIVE NOT RECRUITING Phase 2 80 participants

A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)

Merck Sharp & Dohme

NCT06465186

ACTIVE NOT RECRUITING Phase 2 45 participants

Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study

Northwestern University

NCT04550481

COMPLETED Phase 2 289 participants

Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis

Tobira Therapeutics

NCT02217475

COMPLETED Phase 4 176 participants

University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial)

University of Florida

NCT00994682

COMPLETED Phase 2 106 participants

Saroglitazar Magnesium in Patients With Nonalcoholic Fatty Liver Disease and/or Nonalcoholic Steatohepatitis

Zydus Therapeutics

NCT03061721

COMPLETED 104 participants

The Role of Leptin Receptors in NASH

University of California, Davis

NCT00583999

COMPLETED Phase 2 102 participants

ALG-055009 in Non-cirrhotic Adults With MASH (HERALD)

Aligos Therapeutics

NCT06342947

COMPLETED Phase 2 75 participants

Study of Pharmacodynamics and Safety of DGAT2i and ACCi Coadministered in Participants With Sponsor-defined Presumed Non Alcoholic Steatohepatitis

Pfizer

NCT04399538

COMPLETED NA 24 participants

Feasibility of VIIT in Adults With NASH

Duke University

NCT03861819

COMPLETED NA 21 participants

Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)

Indiana University

NCT00586313

Phase Distribution

PhaseTrial count
Phase 2 9
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Nonalcoholic Steatohepatitis Trial Landscape

ClinicalTrials.gov lists 18 US studies indexed under Nonalcoholic Steatohepatitis, and 6 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Nonalcoholic Steatohepatitis shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Nonalcoholic Steatohepatitis is led by University of Florida with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 18 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Nonalcoholic Steatohepatitis?

PlainTrial tracks 18 US clinical trials for Nonalcoholic Steatohepatitis, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Nonalcoholic Steatohepatitis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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