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NCT01114958 · ClinicalTrials.gov registry record · Phase 1
Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases
A Phase 1 study of Neoplasm Metastasis and Lung Neoplasms, sponsored by University of California, San Diego.
- Completed
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
- 1
- Study location
NCT01114958 is a Phase 1 study of Neoplasm Metastasis and Lung Neoplasms that has completed, run by University of California, San Diego. The registered enrollment target is 8 participants, below the 416-participant average among 41 other Neoplasm Metastasis trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01114958, a Phase 1 study of Neoplasm Metastasis and Lung Neoplasms, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase I study proposes the use of systemic thiosulfate rescue to allow supradose intra-arterial cisplatin delivery to lung tumors. Eligible patients would be those with at least one lung lesion large enough of characterize angiographically. All patients will first undergo a CT arteriogram of the target tumor. Patients will then receive 2 treatments on 2 consecutive weeks. The primary endpoint will be toxicity, with secondary endpoint of response as measured on week 4. This pilot study will also determine how technically feasible it is to locate the blood supply to these tumors and deliver cisplatin. If the first 6 patients do well, 6 additional patients will be accrued for a total of 12.
Conditions Studied
Interventions
- DRUG Cisplatin, Thiosulfate
Study Locations (1)
California
- University of California, San Diego Moores Cancer Center - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2009-09-03 |
| Est. Completion | 2013-05-17 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01114958
The ClinicalTrials.gov registry entry for NCT01114958 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 416-participant average among 41 other Neoplasm Metastasis trials with a reported enrollment target (98% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Neoplasm Metastasis appearing as the primary indexed condition, and to 1 intervention - of which Cisplatin, Thiosulfate is the first listed.
NCT01114958 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT01114958 about?
NCT01114958 is a clinical study titled "Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases". This phase I study proposes the use of systemic thiosulfate rescue to allow supradose intra-arterial cisplatin delivery to lung tumors. Eligible patients would be those with at least one lung lesion large enough of characterize angiographically. All patients will first undergo a CT arteriogram of th...
What is the current status of trial NCT01114958?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2009-09-03. Estimated completion is 2013-05-17.
What conditions does trial NCT01114958 study?
This clinical trial studies the following conditions: Neoplasm Metastasis, Lung Neoplasms.
What interventions are being tested in trial NCT01114958?
The interventions under investigation include: Cisplatin, Thiosulfate (DRUG).
Who is sponsoring clinical trial NCT01114958?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01114958 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.