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ClinicalTrials.gov 27 recruiting now early-phase tilt

Interstitial Lung Disease: early-phase trial registry

27 of 37 indexed Interstitial Lung Disease trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #406 of 28,707 conditions by registered trial count.

37 US clinical trials · 27 currently recruiting · #406 of 28,707 conditions by registered trial count

Interstitial Lung Disease: 37 US clinical trials tracked, 27 recruiting.

Interstitial Lung Disease is the subject of 37 registered US clinical trials on ClinicalTrials.gov, 27 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most active sponsor is Bastiaan Driehuys, running 3 of these trials.

Enrollment posture brief

Registry condition interstitial-lung-disease

OPEN 27 | RECR 73% | LATE 3 | EARLY 17 | RANK #406 | SPON 3

Nearest open-share peer: Adult (73% recruiting · 11 trials)

Interstitial Lung Diseas (th…73%Biliary Tract Cancer64.9%Breastfeeding45.9%Chronic Obstructive Pulmonar29.7%Burns24.3%
Open-enrollment share among volume-matched conditions near Interstitial Lung Disease

Interstitial Lung Disease lists 27 open slots (73% of 37 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Interstitial Lung Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Interstitial Lung Disease is recruiting above its size-band peers.

    27 of 37 indexed trials (73%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Interstitial Lung Disease trials is spread across many organizations.

    Bastiaan Driehuys accounts for 3 of 37 trials (8.1%). 28 distinct sponsors appear on at least one study for this condition label.

  3. Typical Interstitial Lung Disease enrolment sits around 125 participants.

    Median target enrolment is 125 among the 37 trials that report a genuine target (sentinel values excluded). 16 of those (43.2%) plan for fewer than 100 participants.

  4. Interstitial Lung Disease splits between interventional and observational designs.

    24 interventional and 13 observational studies make up this index (64.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 213Phase 32Phase 41

Open and recent trials

37 total, page 1 of 1

RECRUITING 10,000 participants

Pulmonary Fibrosis Foundation Community Registry

Pulmonary Fibrosis Foundation

NCT05382572

RECRUITING 2,122 participants

WTC Chest CT Imaging Archive

Icahn School of Medicine at Mount Sinai

NCT03295279

RECRUITING 1,000 participants

Interstitial Lung Disease Research Unit Biobank

University of Kansas Medical Center

NCT05392881

RECRUITING 1,000 participants

DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

United Therapeutics

NCT06388421

RECRUITING 750 participants

Rheumatoid Arthritis Patients at Risk for Interstitial Lung Disease

University of Colorado, Denver

NCT03297775

RECRUITING Phase 3 698 participants

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

United Therapeutics

NCT05943535

RECRUITING 635 participants

Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD)

Mayo Clinic

NCT03478826

RECRUITING 500 participants

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

University of Massachusetts, Worcester

NCT06855329

RECRUITING 450 participants

Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease

University of Colorado, Denver

NCT06397677

RECRUITING Phase 2 445 participants

Hyperpolarized 129Xe MRI for Imaging Pulmonary Function

Bastiaan Driehuys

NCT01280994

RECRUITING Phase 3 344 participants

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Insmed Incorporated

NCT07179380

RECRUITING 300 participants

Pulmonary Hypertension Screening in Patients With Interstitial Lung Disease for Earlier Detection

United Therapeutics

NCT05776225

RECRUITING Phase 1 260 participants

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

Mario Castro, MD, MPH

NCT04624490

RECRUITING NA 170 participants

SUPPORT-T in Patients With Progressive Pulmonary Fibrosis and Their Caregivers

Medical University of South Carolina

NCT07269262

RECRUITING Phase 2 125 participants

129Xe MRI Cardiopulmonary

Bastiaan Driehuys

NCT06038630

RECRUITING 100 participants

Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research

Baylor Research Institute

NCT04664192

RECRUITING Phase 2 38 participants

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

Children's Hospital Medical Center, Cincinnati

NCT04925375

RECRUITING Phase 2 37 participants

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

National Institute of Environmental Health Sciences (NIEHS)

NCT06325696

RECRUITING Phase 2 30 participants

Pulmonary Hypertension SOLAR

Bastiaan Driehuys

NCT04778046

RECRUITING Early Phase 1 30 participants

FAPI PET for Lung Fibrosis

University of California, Los Angeles

NCT05365802

RECRUITING NA 30 participants

Telehealth and Onsite Maintenance Exercise in Chronic Lung Disease

MGH Institute of Health Professions

NCT06304207

RECRUITING Phase 2 30 participants

Collagen-targeted PET Imaging for Early Interstitial Lung Disease

Massachusetts General Hospital

NCT05417776

RECRUITING Phase 2 25 participants

A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung Disease

Memorial Sloan Kettering Cancer Center

NCT07323732

RECRUITING Phase 2 25 participants

Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough

Mayo Clinic

NCT05120934

RECRUITING Phase 2 25 participants

Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

aTyr Pharma

NCT05892614

RECRUITING Phase 2 8 participants

Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

Paul Szabolcs

NCT03630211

RECRUITING Phase 1 8 participants

Feasibility of Semaglutide in Advanced Lung Disease

University of Pennsylvania

NCT05746039

ACTIVE NOT RECRUITING 400 participants

Genentech Validation Tool for Pulmonary Fibrosis

Columbia University

NCT04676594

ACTIVE NOT RECRUITING Phase 2 154 participants

Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007)

Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT05270668

ACTIVE NOT RECRUITING Phase 2 135 participants

A Study of Mosliciguat in PH-ILD

Pulmovant

NCT06635850

ACTIVE NOT RECRUITING 80 participants

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH

Liquidia Technologies

NCT06129240

COMPLETED 207 participants

Autologous Stem Cell Treatment for Chronic Lung Disease Study

Lung Institute

NCT03044431

COMPLETED Phase 4 121 participants

The Study of the Use of Nintedanib in Slowing Lung Disease in Patients With Fibrotic or Non-Fibrotic Interstitial Lung Disease Related to COVID-19

Icahn School of Medicine at Mount Sinai

NCT04619680

COMPLETED Phase 2 51 participants

Scleroderma Lung Study III - Combining Pirfenidone With Mycophenolate

Michael Roth

NCT03221257

COMPLETED NA 43 participants

Palliative Care Planner (PCplanner)

Duke University

NCT05095363

COMPLETED NA 14 participants

Comparison of Transbronchial, Cryoprobe and VATS Biopsy For the Diagnosis of Interstitial Lung Disease (ILD)

Duke University

NCT01972685

COMPLETED Phase 1 10 participants

Allogeneic Bone Marrow Mesenchymal Stem Cells for Patients With Interstitial Lung Disease (ILD) & Connective Tissue Disorders (CTD)

Mayo Clinic

NCT03929120

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 13
Phase 3 2
Phase 4 1

Named interventions

Most-linked intervention names on Interstitial Lung Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
Hyperpolarized Xe129 Drug
2 trials
Placebo (Plac) Drug
1 trials
Pirfenidone (PFD) Drug
1 trials
Allogeneic Bone Marrow Derived Mesenchymal Stem Cells (BMD-MSCs) Biological
1 trials
VATS biopsy Procedure
1 trials
Transbronchial Biopsy Procedure
1 trials
Cryobiopsy biopsy Procedure
1 trials

US sites by state

Facility locations filed on Interstitial Lung Disease trials. A trial with sites in several states counts in each.

California 10 trials
Texas 9 trials
New York 9 trials
Florida 9 trials
North Carolina 8 trials
Illinois 7 trials
South Carolina 6 trials
Michigan 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Interstitial Lung Disease page

37 registered trials, 27 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 27 Interstitial Lung Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Bastiaan Driehuys sponsors the most Interstitial Lung Disease trials on record, review their full trial history before evaluating a specific study. See Bastiaan Driehuys's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Interstitial Lung Disease condition card totals 37 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.