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Insomnia clinical trials
62 of 152 indexed Insomnia trials are currently recruiting.
152 US clinical trials · 62 currently recruiting
Insomnia is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 62 of them currently open to new participants. 17 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 9 of these trials.
The research picture
Insomnia has 152 registered US clinical trials, 62 of them open to new participants right now, about 41% of the total.
- 62
- recruiting participants now
- 41%
- of trials open to enrollment
- 17
- in Phase 3–4 (later-stage)
- 9
- top sponsor: VA Office of Research and Development
Active & Recent Trials
152 total, page 2 of 4
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
Massachusetts General Hospital
NCT06375265
Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia
St. Jude Children's Research Hospital
NCT07191119
Digital Cognitive Behavioral Treatment of Insomnia in Youth: An RCT Examining Feasibility, Acceptability, and Efficacy of NiteCAPP Jr
University of South Florida
NCT07091149
Assessing the Feasibility of Web-based Insomnia Treatment Among Prostate Cancer Survivors
Georgetown University
NCT07128927
Implementation & Dissemination of a Digital Health Intervention for Adolescent Sleep
University of Kansas Medical Center
NCT06840444
Mindfulness Meditation for Insomnia
Brigham and Women's Hospital
NCT06972303
Treating Insomnia in Mild Cognitive Impairment
Beth Israel Deaconess Medical Center
NCT06687161
Adapted CBT-I for Adolescents With Insomnia : The DREAM-IT Study
Indiana University
NCT06541886
Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder
University of California, Los Angeles
NCT05499741
Novel Adaptive Cognitive Training in Autistic Adults with Co-occurring Insomnia
University of South Florida
NCT06291298
CBTi for the Treatment of Insomnia in Type 1 Diabetes
University of Illinois at Chicago
NCT07091318
LiverSleep: A Behavioral Sleep Intervention for Patients With Cirrhosis and Insomnia
Massachusetts General Hospital
NCT07417163
The Assessment of Human Sleep and Its Functions
StimScience
NCT07211646
National Adaptive Trial for PTSD Related Insomnia
VA Office of Research and Development
NCT03668041
Perinatal Research on Improving Sleep and Mental Health
University of California, San Francisco
NCT05596318
Remote STATE Training for Insomnia in Older Adults
Posit Science Corporation
NCT06589024
Intervention for Sleep and Pain in Youth: a Randomized Controlled Trial
Seattle Children's Hospital
NCT04936321
Evaluation of a Neurostimulation Device for Insomnia: A Randomized Trial
ProofPilot
NCT04627480
CBT-I to Improve Functional Outcomes in Veterans With Psychosis
VA Office of Research and Development
NCT04646200
Targeting Sleep Homeostasis to Improve Alcohol Use Disorder Treatment Outcomes (M-STAR Study)
University of Michigan
NCT04457674
Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)
Henry Ford Health System
NCT05356364
Effects of Mirtazapine on Appetite in Advanced Cancer Patients
M.D. Anderson Cancer Center
NCT00488072
Neurotechnology Following Traumatic Brain Injury
Brain State Technologies
NCT03649958
Solriamfetol and CBT-I in Patients With Insomnia Disorder
University of Pennsylvania
NCT05838430
A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors
University of Washington
NCT06392789
Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application
Brigham and Women's Hospital
NCT05991492
Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study
University of Kansas Medical Center
NCT07008924
Comparing Virtual Yoga to Standard Care on Insomnia Among Cancer Survivors
University of Rochester
NCT04458194
Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders
University of Arizona
NCT03540745
Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study
Stanford University
NCT02037438
Yoga, Survivorship Health Education, and Cognitive Behavioral Therapy in Reducing Insomnia in Cancer Survivors
University of Rochester NCORP Research Base
NCT02613364
A Study of Eszopiclone in Subjects With Insomnia Related to Major Depressive Disorder
Sumitomo Pharma America
NCT00368030
Hypertension With Unsatisfactory Sleep Health
University of Pittsburgh
NCT02508129
Safety and Efficacy of Eszopiclone in Patients With Generalized Anxiety Disorder
Sumitomo Pharma America
NCT00235508
Effects Of GW679769 On Sleep Onset And Maintenance And Next Day Functioning In Subjects With Primary Insomnia
GlaxoSmithKline
NCT00280423
Reducing Health Disparities for Black Women in the Treatment of Insomnia
Boston University
NCT03613519
Sleep Healthy Using The Internet for Older Adult Sufferers of Insomnia and Sleeplessness
University of Virginia
NCT03213132
Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia
Sumitomo Pharma America
NCT00857220
Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire
Dayzz Live Well
NCT03468400
Research on Expecting Moms and Sleep Therapy
University of California, San Francisco
NCT02805998
Partial Reinforcement II: Three Approaches to Maintenance Therapy for Chronic Insomnia
University of Pennsylvania
NCT03774810
Impact of Sleep Workshops in College Students
NYU Langone Health
NCT02665247
Safety and Efficacy Study of APD125 in Patient With Insomnia
Arena Pharmaceuticals
NCT00452179
Preventing Insomnia With Virtual Oneshot Therapy (PIVOT)
Henry Ford Health System
NCT05523726
Choosing Options for Insomnia in Cancer Effectively (CHOICE): A Comparative Effectiveness Trial of Acupuncture and Cognitive Behavior Therapy
Memorial Sloan Kettering Cancer Center
NCT02356575
Treatments for Insomnia: Mediators, Moderators and Quality of Life
Palo Alto Veterans Institute for Research
NCT02117388
Short and Long-Term Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis
University of Washington
NCT03534284
Dual Treatment of Chronic Pain and Insomnia
Mary Free Bed Rehabilitation Hospital
NCT05033418
Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes
Massachusetts General Hospital
NCT03818581
Optimizing Efficiency and Impact of Digital Health Interventions for Caregivers
University of Virginia
NCT04986904
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 16 |
| Phase 3 | 5 |
| Phase 4 | 12 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Insomnia Trial Landscape
152 indexed Insomnia studies · 62 recruiting (41%).
Phase mix: 17 late (III/IV) vs 21 early (I/II).
Top sponsor: VA Office of Research and Development (9 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Insomnia?
PlainTrial tracks 152 US clinical trials for Insomnia, of which 62 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Insomnia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.