Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 6 recruiting now later-stage tilt small index

Hypotension: later-stage trial registry

6 of 13 indexed Hypotension trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 6 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Hypotension: 13 US clinical trials tracked, 6 recruiting.

Hypotension is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Kessler Foundation, running 2 of these trials.

Enrollment posture brief

Registry condition hypotension

OPEN 6 | RECR 46% | LATE 4 | EARLY 0 | RANK #1315 | SPON 2

Nearest open-share peer: B-cell Lymphoma (46% recruiting · 39 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Hypotension (this)46%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Hypotension

Hypotension lists 6 open slots (46% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hypotension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hypotension recruits in line with its size-band peers.

    6 of 13 indexed trials (46.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Hypotension research.

    Kessler Foundation accounts for 2 of 13 trials (15.4%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most Hypotension trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 13 trials that report a genuine target (sentinel values excluded). 9 of those (69.2%) plan for fewer than 100 participants.

  4. Hypotension splits between interventional and observational designs.

    8 interventional and 5 observational studies make up this index (61.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 31Phase 43

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 4 100 participants

Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV

West-Ward Pharmaceutical

NCT02323399

RECRUITING 80 participants

Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS

Massachusetts General Hospital

NCT06994494

RECRUITING NA 50 participants

TSCS for Acute SCI

Icahn School of Medicine at Mount Sinai

NCT05305118

RECRUITING Phase 4 25 participants

Treatment of Orthostatic Hypotension in SCI

James J. Peters Veterans Affairs Medical Center

NCT05839652

RECRUITING NA 12 participants

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

Kessler Foundation

NCT05731986

RECRUITING NA 5 participants

The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

Kessler Foundation

NCT05725499

ACTIVE NOT RECRUITING 200 participants

Effects of Transitional Circulation in ELBW Infants

University of Iowa

NCT02016599

ACTIVE NOT RECRUITING 124 participants

Use of Ultrasonography to Determine Fluid-responsiveness for Shock in a Population of Intensive Care Unit Patients

University of Chicago

NCT01680770

ACTIVE NOT RECRUITING 50 participants

Hypotension Prediction Index: Correlations Between Invasive and Non-invasive Pressure Points.

University of California, Davis

NCT05025176

COMPLETED Phase 3 200 participants

Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion

Eli Lilly and Company

NCT00190788

COMPLETED NA 51 participants

Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs

Milton S. Hershey Medical Center

NCT02624050

COMPLETED Phase 4 40 participants

Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach

University of Colorado, Denver

NCT02135146

COMPLETED 26 participants

Measuring Cardiovascular Stress in Patients on Hemodialysis

West Penn Allegheny Health System

NCT01267617

Phase Distribution

PhaseTrial count
Phase 3 1
Phase 4 3

Named interventions

Most-linked intervention names on Hypotension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Drotrecogin Alfa (Activated) Drug
1 trials
Methohexital Drug
1 trials
Plasmalyte 6ml/kg/hr group Drug
1 trials
Plasmalyte 3ml/kg/hr group Drug
1 trials
Non invasive arterial pressure monitoring Device
1 trials
Monitoring and biospecimen collection Other
1 trials
Midodrine Hydrochloride Drug
1 trials
Transcutaneous spinal cord stimulation Device
1 trials

US sites by state

Facility locations filed on Hypotension trials. A trial with sites in several states counts in each.

New York 3 trials
New Jersey 3 trials
Pennsylvania 2 trials
California 2 trials
West Virginia 1 trials
Washington 1 trials
Texas 1 trials
Ohio 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hypotension page

13 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hypotension condition card totals 13 registered trials; most-linked intervention Drotrecogin Alfa (Activated); top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.