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NCT01680770 · ClinicalTrials.gov registry record
Use of Ultrasonography to Determine Fluid-responsiveness for Shock in a Population of Intensive Care Unit Patients
A clinical trial of Hypotension, sponsored by University of Chicago.
- Active
- Registry status
- 124
- Enrollment target
- 1
- Study location
NCT01680770: Active study of Hypotension, sponsored by University of Chicago.
NCT01680770 is a study of Hypotension that is active but no longer recruiting, run by University of Chicago. The registered enrollment target is 124 participants, above the 70-participant average among 12 other Hypotension trials with a reported enrollment target (77% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01680770, a study of Hypotension, is active but no longer recruiting, sponsored by University of Chicago.
- ACTIVE NOT RECRUITING
- Registry status
- 124 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of our study is to determine the correlation of transthoracic ultrasonographic indices of fluid responsiveness to changes in direct measures of cardiac output and to compare them to other established predictors of fluid responsiveness such as central venous pressure variation, systolic arterial pressure variation and pulse pressure variation in a broad population of patients. Hypothesis: There will be a significant difference in the inferior vena cava respiratory variation and subclavian vein respiratory variation between responders and non-responders to intravenous fluid challenge in a broad population of patients with shock.
Primary Outcome
Patients will be divided into responder and non-responder groups based on an increase in cardiac output of greater than or equal to 15% as measured by thermodilution from a right heart catheter in response to a one liter normal saline fluid bolus.
Conditions Studied
Study Locations (1)
Illinois
- The University of Chicago Medical Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 124 participants |
| Start Date | 2010-06 |
| Est. Completion | 2026-08 |
What the registry record for NCT01680770 still lists
NCT01680770 is an observational study that tracks outcomes without assigning an intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, above the 70-participant average among 12 other Hypotension trials with a reported enrollment target (77% higher).
The record links to 1 condition, with Hypotension appearing as the primary indexed condition, and to 0 interventions.
NCT01680770 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01680770 about?
NCT01680770 is a clinical study titled "Use of Ultrasonography to Determine Fluid-responsiveness for Shock in a Population of Intensive Care Unit Patients". The objective of our study is to determine the correlation of transthoracic ultrasonographic indices of fluid responsiveness to changes in direct measures of cardiac output and to compare them to other established predictors of fluid responsiveness such as central venous pressure variation, systolic...
What is the current status of trial NCT01680770?
This trial is currently active not recruiting. The enrollment target is 124 participants. The study started on 2010-06. Estimated completion is 2026-08.
What conditions does trial NCT01680770 study?
This clinical trial studies the following conditions: Hypotension.
Who is sponsoring clinical trial NCT01680770?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01680770 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01680770's enrollment target sits among peer trials
124 3rd of 12 higher than 10 of 12 other Hypotension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypotension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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