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NCT00190788 · ClinicalTrials.gov registry record · Phase 3
Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion
A Phase 3 study of Sepsis and Hypotension, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 3
- Development phase
- 200
- Enrollment target
- 2
- Study locations
NCT00190788: Completed Phase 3 study of Sepsis and Hypotension, sponsored by Eli Lilly and Company.
NCT00190788 is a Phase 3 study of Sepsis and Hypotension that has completed, run by Eli Lilly and Company. The registered enrollment target is 200 participants, below the 6,562-participant average among 90 other Sepsis trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00190788, a Phase 3 study of Sepsis and Hypotension, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 200 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to determine whether continued administration of Drotrecogin Alfa (Activated) up to additional 72 hours - after the so far recommended 96 hour infusion period - results in a more rapid resolution of hypotension in severe septic patients.
Conditions Studied
Interventions
- DRUG placebo
- DRUG Drotrecogin Alfa (Activated)
Study Locations (2)
California
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Loma Linda
Other
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. - Paris
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2004-06 |
| Est. Completion | 2007-05 |
| Phase | Phase 3 |
What the finished NCT00190788 record still lists
NCT00190788 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 6,562-participant average among 90 other Sepsis trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Sepsis appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.
NCT00190788 reports a single indexed study location in California, Other.
Frequently Asked Questions
What is clinical trial NCT00190788 about?
NCT00190788 is a clinical study titled "Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion". The purpose of this study is to determine whether continued administration of Drotrecogin Alfa (Activated) up to additional 72 hours - after the so far recommended 96 hour infusion period - results in a more rapid resolution of hypotension in severe septic patients.
What is the current status of trial NCT00190788?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 200 participants. The study started on 2004-06. Estimated completion is 2007-05.
What conditions does trial NCT00190788 study?
This clinical trial studies the following conditions: Sepsis, Hypotension.
What interventions are being tested in trial NCT00190788?
The interventions under investigation include: placebo (DRUG), Drotrecogin Alfa (Activated) (DRUG).
Who is sponsoring clinical trial NCT00190788?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00190788 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sepsis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00190788's enrollment target sits among peer trials
200 42nd of 90 higher than 46 of 90 other Sepsis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sepsis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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