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NCT05839652 · ClinicalTrials.gov registry record · Phase 4

Treatment of Orthostatic Hypotension in SCI

A Phase 4 study of Hypotension, sponsored by James J. Peters Veterans Affairs Medical Center.

Recruiting
Registry status
Phase 4
Development phase
25
Enrollment target
2
Study locations

NCT05839652: Recruiting Phase 4 study of Hypotension, sponsored by James J. Peters Veterans Affairs Medical Center.

NCT05839652 is a Phase 4 study of Hypotension that is actively recruiting participants, run by James J. Peters Veterans Affairs Medical Center. The registered enrollment target is 25 participants, below the 78-participant average among 12 other Hypotension trials with a reported enrollment target (68% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05839652, a Phase 4 study of Hypotension, is actively recruiting participants, sponsored by James J. Peters Veterans Affairs Medical Center.

RECRUITING
Registry status
Phase 4
Development phase
25 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

Primary Outcome

determine differences in systolic blood pressure after midodrine, droxidopa, compression stockings and placebo

Conditions Studied

Interventions

  • DRUG Midodrine Hydrochloride

Study Locations (2)

New Jersey

  • Kessler Foundation - West Orange

New York

  • James J Peters VA Medical Center - The Bronx

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2023-07-01
Est. Completion 2026-06-30
Phase Phase 4

What NCT05839652 shows while recruiting

NCT05839652 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 78-participant average among 12 other Hypotension trials with a reported enrollment target (68% lower).

The record links to 1 condition, with Hypotension appearing as the primary indexed condition, and to 1 intervention - of which Midodrine Hydrochloride is the first listed.

NCT05839652 reports a single indexed study location in New Jersey, New York.

Frequently Asked Questions

What is clinical trial NCT05839652 about?

NCT05839652 is a clinical study titled "Treatment of Orthostatic Hypotension in SCI". The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals w...

What is the current status of trial NCT05839652?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 25 participants. The study started on 2023-07-01. Estimated completion is 2026-06-30.

What conditions does trial NCT05839652 study?

This clinical trial studies the following conditions: Hypotension.

What interventions are being tested in trial NCT05839652?

The interventions under investigation include: Midodrine Hydrochloride (DRUG).

Who is sponsoring clinical trial NCT05839652?

This trial is sponsored by James J. Peters Veterans Affairs Medical Center, which has 39 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05839652 being conducted?

This trial has 2 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hypotension

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05839652's enrollment target sits among peer trials

25 11th of 12 higher than 2 of 12 other Hypotension trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hypotension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05839652, the US trial registry maintained by the National Library of Medicine. NCT05839652 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.