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Human Papilloma Virus clinical trials
10 of 27 indexed Human Papilloma Virus trials are currently recruiting.
27 US clinical trials · 10 currently recruiting
Human Papilloma Virus is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is UNC Lineberger Comprehensive Cancer Center, running 2 of these trials.
The research picture
Human Papilloma Virus has 27 registered US clinical trials, 10 of them open to new participants right now, about 37% of the total.
- 10
- recruiting participants now
- 37%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: UNC Lineberger Comprehensive Cancer Center
Active & Recent Trials
27 total, page 1 of 1
Prevention of Cervical Cancer Using the Genotyping Screening and Same-day Self-sampling
Atila Biosystems
NCT07232355
Educate and Improve Underserved Populations' Uptake and Completion of the HPV Vaccine
University of Colorado, Denver
NCT04611022
Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma
Stanford University
NCT05880797
Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study
Emory University
NCT05065840
A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer
Memorial Sloan Kettering Cancer Center
NCT05491512
Evaluating Gardasil HPV Vaccine Humoral and Cellular Immune Responses in People With and Without HIV
University of Maryland, Baltimore
NCT06624839
PopSci CHW4CervixHealth
Thomas Jefferson University
NCT07336134
TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers
University of Chicago
NCT05108870
Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery
Ryan Carey
NCT06747390
Merck IIT: RRP Pembro and Lenvatinib
Yale University
NCT04645602
Men and Women Offering Understanding of Throat HPV
Johns Hopkins University
NCT03644563
GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose
The University of Texas Medical Branch, Galveston
NCT03943875
Development of a Self-collection Device for Cervical Cancer Screening
Teal Health
NCT05669911
Immunogenicity of the 9vHPV Vaccination 2-dose Regimen Among Children 4 to 8 Years Old
Boston Medical Center
NCT05329961
TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck
Abramson Cancer Center at Penn Medicine
NCT03729518
Impact of Financial Incentives
UNC Lineberger Comprehensive Cancer Center
NCT05744960
Impact of Standing Orders Optimization
UNC Lineberger Comprehensive Cancer Center
NCT05742386
Text Reminders to Immunize in a Managed Care Organization
University of Rochester
NCT01806714
HPV Message Testing and Social Media Campaign
Dartmouth-Hitchcock Medical Center
NCT03747302
High and Low Resource Interventions to Promote HPV Vaccines
Children's Mercy Hospital Kansas City
NCT03824093
PreTeenVax Evaluation
Emory University
NCT03186430
The Sinai Robotic Surgery Trial in HPV Positive Oropharyngeal Squamous Cell Carcinoma (SCCA) (SIRS TRIAL)
Icahn School of Medicine at Mount Sinai
NCT02072148
Candin Safety & Efficacy Study for the Treatment of Warts
Nielsen BioSciences
NCT01757392
Safety and Efficacy of MEDI0457 and Durvalumab in Participants With Human Papilloma Virus (HPV) Associated Recurrent/Metastatic Head and Neck Cancer
MedImmune
NCT03162224
De-Escalation Therapy for Human Papillomavirus Negative Disease
University of Chicago
NCT03944915
Avelumab for People With Recurrent Respiratory Papillomatosis
National Cancer Institute (NCI)
NCT02859454
Intralesional HPV Vaccine for Condylomata
University of California, San Francisco
NCT05087849
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 5 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Human Papilloma Virus Trial Landscape
27 indexed Human Papilloma Virus studies · 10 recruiting (37%).
Phase mix: 1 late (III/IV) vs 11 early (I/II).
Top sponsor: UNC Lineberger Comprehensive Cancer Center (2 trials), 9 others listed. 27 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Human Papilloma Virus?
PlainTrial tracks 27 US clinical trials for Human Papilloma Virus, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Human Papilloma Virus?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.