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ClinicalTrials.gov 14 recruiting now early-phase tilt

Human Papilloma Virus: early-phase trial registry

14 of 40 indexed Human Papilloma Virus trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #368 of 28,707 conditions by registered trial count.

40 US clinical trials · 14 currently recruiting · #368 of 28,707 conditions by registered trial count

Human Papilloma Virus: 40 US clinical trials tracked, 14 recruiting.

Human Papilloma Virus is the subject of 40 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is The University of Texas Medical Branch, Galveston, running 2 of these trials.

Enrollment posture brief

Registry condition human-papilloma-virus

OPEN 14 | RECR 35% | LATE 2 | EARLY 13 | RANK #368 | SPON 2

Nearest open-share peer: Diet Modification (35% recruiting · 20 trials)

Anatomic Stage IIIA Breast C35%Human Papilloma Virus (this)35%Human Immunodeficiency Virus30%Heart Failure, Congestive12.5%Cocaine Dependence7.5%
Open-enrollment share among volume-matched conditions near Human Papilloma Virus

Human Papilloma Virus lists 14 open slots (35% of 40 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Human Papilloma Virus on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Human Papilloma Virus is recruiting below its size-band peers.

    14 of 40 indexed trials (35%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Human Papilloma Virus trials is spread across many organizations.

    The University of Texas Medical Branch, Galveston accounts for 2 of 40 trials (5%). 34 distinct sponsors appear on at least one study for this condition label.

  3. Typical Human Papilloma Virus enrolment sits around 155 participants.

    Median target enrolment is 155 among the 40 trials that report a genuine target (sentinel values excluded). 12 of those (30%) plan for fewer than 100 participants.

  4. Human Papilloma Virus research is mostly interventional.

    30 interventional and 10 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 26Phase 42

Open and recent trials

40 total, page 1 of 1

RECRUITING NA 301,201 participants

Provider Recommendation and HPV Vaccination

Kaiser Permanente

NCT05365048

RECRUITING 5,000 participants

Prevention of Cervical Cancer Using the Genotyping Screening and Same-day Self-sampling

Atila Biosystems

NCT07232355

RECRUITING NA 1,000 participants

Educate and Improve Underserved Populations' Uptake and Completion of the HPV Vaccine

University of Colorado, Denver

NCT04611022

RECRUITING 1,000 participants

Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma

Stanford University

NCT05880797

RECRUITING 850 participants

Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05026138

RECRUITING Phase 4 618 participants

Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)

The University of Texas Medical Branch, Galveston

NCT05672927

RECRUITING 600 participants

Evaluation of a Novel Point-of-Care Diagnostic Test for Human Papillomavirus (HPV)

M.D. Anderson Cancer Center

NCT06434337

RECRUITING NA 365 participants

Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study

Emory University

NCT05065840

RECRUITING Phase 2 121 participants

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

Memorial Sloan Kettering Cancer Center

NCT05491512

RECRUITING Phase 2 120 participants

Evaluating Gardasil HPV Vaccine Humoral and Cellular Immune Responses in People With and Without HIV

University of Maryland, Baltimore

NCT06624839

RECRUITING NA 120 participants

PopSci CHW4CervixHealth

Thomas Jefferson University

NCT07336134

RECRUITING Phase 1 98 participants

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

University of Chicago

NCT05108870

RECRUITING Phase 1 30 participants

Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

Ryan Carey

NCT06747390

RECRUITING Early Phase 1 20 participants

Merck IIT: RRP Pembro and Lenvatinib

Yale University

NCT04645602

ACTIVE NOT RECRUITING 1,500 participants

Men and Women Offering Understanding of Throat HPV

Johns Hopkins University

NCT03644563

ACTIVE NOT RECRUITING Phase 4 767 participants

GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose

The University of Texas Medical Branch, Galveston

NCT03943875

ACTIVE NOT RECRUITING NA 235 participants

Development of a Self-collection Device for Cervical Cancer Screening

Teal Health

NCT05669911

ACTIVE NOT RECRUITING Early Phase 1 155 participants

Immunogenicity of the 9vHPV Vaccination 2-dose Regimen Among Children 4 to 8 Years Old

Boston Medical Center

NCT05329961

ACTIVE NOT RECRUITING NA 150 participants

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

Abramson Cancer Center at Penn Medicine

NCT03729518

ACTIVE NOT RECRUITING Phase 1 55 participants

A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers

National Cancer Institute (NCI)

NCT04708470

ACTIVE NOT RECRUITING NA 34 participants

Impact of Financial Incentives

UNC Lineberger Comprehensive Cancer Center

NCT05744960

ACTIVE NOT RECRUITING NA 28 participants

Impact of Standing Orders Optimization

UNC Lineberger Comprehensive Cancer Center

NCT05742386

COMPLETED 6,730 participants

Longitudinal Clinical Evaluation of the HPV Assay on the BD VIPER LT System With Cervical Specimens

Becton, Dickinson and Company

NCT02267876

COMPLETED NA 3,812 participants

Text Reminders to Immunize in a Managed Care Organization

University of Rochester

NCT01806714

COMPLETED NA 1,043 participants

HPV Message Testing and Social Media Campaign

Dartmouth-Hitchcock Medical Center

NCT03747302

COMPLETED 1,000 participants

A Retrospective Chart Review Study of Gene-Eden-VIR/Novirin

The Center for the Biology of Chronic Disease

NCT02715752

COMPLETED 900 participants

Natural History of HPV From Infection to Neoplasia in Adolescents and Young Women

University of California, Los Angeles

NCT01366742

COMPLETED 587 participants

Human Papillomavirus (HPV) Vaccination Among Survivors of Childhood Cancer

St. Jude Children's Research Hospital

NCT01117389

COMPLETED NA 225 participants

High and Low Resource Interventions to Promote HPV Vaccines

Children's Mercy Hospital Kansas City

NCT03824093

COMPLETED NA 168 participants

PreTeenVax Evaluation

Emory University

NCT03186430

COMPLETED NA 150 participants

txt2protect: Using Text Messaging to Increase HPV Vaccination Among Young Sexual Minority Men

Northwestern University

NCT02994108

COMPLETED Phase 2 150 participants

Study of Gardasil in Mid-Adult Males (MAM)

H. Lee Moffitt Cancer Center and Research Institute

NCT01432574

COMPLETED NA 112 participants

The Sinai Robotic Surgery Trial in HPV Positive Oropharyngeal Squamous Cell Carcinoma (SCCA) (SIRS TRIAL)

Icahn School of Medicine at Mount Sinai

NCT02072148

COMPLETED NA 110 participants

Video to Promote HPV Vaccination

Children's Hospital of Philadelphia

NCT02196454

COMPLETED Phase 2 39 participants

Candin Safety & Efficacy Study for the Treatment of Warts

Nielsen BioSciences

NCT01757392

COMPLETED Phase 1 35 participants

Safety and Efficacy of MEDI0457 and Durvalumab in Participants With Human Papilloma Virus (HPV) Associated Recurrent/Metastatic Head and Neck Cancer

MedImmune

NCT03162224

COMPLETED Phase 2 35 participants

De-Escalation Therapy for Human Papillomavirus Negative Disease

University of Chicago

NCT03944915

COMPLETED 33 participants

Role of Immune Activation in Response of Head and Neck Squamous Cell Carcinoma to Therapy

Icahn School of Medicine at Mount Sinai

NCT01358097

COMPLETED Phase 2 13 participants

Avelumab for People With Recurrent Respiratory Papillomatosis

National Cancer Institute (NCI)

NCT02859454

COMPLETED Phase 1 2 participants

Intralesional HPV Vaccine for Condylomata

University of California, San Francisco

NCT05087849

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 6
Phase 4 2

Named interventions

Most-linked intervention names on Human Papilloma Virus records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Carboplatin Drug
3 trials
Communication training Behavioral
2 trials
9-valent HPV vaccine, 3 doses standard timing Biological
2 trials
Radiation Radiation
2 trials
Paclitaxel Drug
2 trials
nonavalent human papillomavirus vaccine Biological
1 trials
Gene-Eden-VIR/Novirin Dietary supplement
1 trials
Gardasil Biological
1 trials

US sites by state

Facility locations filed on Human Papilloma Virus trials. A trial with sites in several states counts in each.

California 8 trials
Maryland 7 trials
New York 6 trials
Pennsylvania 5 trials
Texas 4 trials
Illinois 4 trials
Georgia 4 trials
North Carolina 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Human Papilloma Virus page

40 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Human Papilloma Virus condition card totals 40 registered trials; most-linked intervention Carboplatin; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.