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NCT05672927 · ClinicalTrials.gov registry record · Phase 4

Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)

A Phase 4 study of HPV Infection and Human Papillomavirus, sponsored by The University of Texas Medical Branch, Galveston.

Recruiting
Registry status
Phase 4
Development phase
618
Enrollment target
1
Study location

NCT05672927 is a Phase 4 study of HPV Infection and Human Papillomavirus that is actively recruiting participants, run by The University of Texas Medical Branch, Galveston. The registered enrollment target is 618 participants, above the 189-participant average among 13 other HPV Infection trials with a reported enrollment target (227% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT05672927, a Phase 4 study of HPV Infection and Human Papillomavirus, is actively recruiting participants, sponsored by The University of Texas Medical Branch, Galveston.

RECRUITING
Registry status
Phase 4
Development phase
618 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to compare a 2-dose and 3-dose series of 9vHPV vaccine among 27-45-year-old females to assess if 2 doses elicit a noninferior immune response. Participants will be randomized 1:1 to either the 2-dose group or the 3-dose group and asked to provide 4 blood samples over a period of 12 months. All 2-dose participants will be offered a 3rd dose after the final blood draw,12 months after their initial vaccination.

Interventions

  • BIOLOGICAL 9-valent HPV vaccine, 2 doses alternate timing
  • BIOLOGICAL 9-valent HPV vaccine, 3 doses standard timing

Study Locations (1)

Texas

  • University of Texas Medical Branch - Galveston

Trial Details

FieldValue
Enrollment Target 618 participants
Start Date 2023-01-18
Est. Completion 2027-08
Phase Phase 4

What the Registry Record Tells You About NCT05672927

The ClinicalTrials.gov registry entry for NCT05672927 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 618 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 189-participant average among 13 other HPV Infection trials with a reported enrollment target (227% higher). The listed sponsor is The University of Texas Medical Branch, Galveston, which has 203 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with HPV Infection appearing as the primary indexed condition, and to 2 interventions - of which 9-valent HPV vaccine, 2 doses alternate timing is the first listed.

NCT05672927 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05672927 about?

NCT05672927 is a clinical study titled "Comparing Immune Response of 2 vs 3 HPV Doses (27-45 Years Old)". The goal of this clinical trial is to compare a 2-dose and 3-dose series of 9vHPV vaccine among 27-45-year-old females to assess if 2 doses elicit a noninferior immune response. Participants will be randomized 1:1 to either the 2-dose group or the 3-dose group and asked to provide 4 blood samples ov...

What is the current status of trial NCT05672927?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 618 participants. The study started on 2023-01-18. Estimated completion is 2027-08.

What conditions does trial NCT05672927 study?

This clinical trial studies the following conditions: HPV Infection, Human Papillomavirus, Immunization.

What interventions are being tested in trial NCT05672927?

The interventions under investigation include: 9-valent HPV vaccine, 2 doses alternate timing (BIOLOGICAL), 9-valent HPV vaccine, 3 doses standard timing (BIOLOGICAL).

Who is sponsoring clinical trial NCT05672927?

This trial is sponsored by The University of Texas Medical Branch, Galveston, which has 203 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05672927 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.