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ClinicalTrials.gov 15 recruiting now early-phase tilt

HIV/AIDS: early-phase trial registry

15 of 62 indexed HIV/AIDS trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #228 of 28,707 conditions by registered trial count.

62 US clinical trials · 15 currently recruiting · #228 of 28,707 conditions by registered trial count

HIV/AIDS: 62 US clinical trials tracked, 15 recruiting.

HIV/AIDS is the subject of 62 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 7 of these trials.

Enrollment posture brief

Registry condition hivaids

OPEN 15 | RECR 24% | LATE 1 | EARLY 8 | RANK #228 | SPON 7

Nearest open-share peer: Myopia (24% recruiting · 91 trials)

Cognitive Decline58.1%Myelofibrosis46.8%Delirium38.1%Lymphoma, Non-Hodgkin25.8%HIV/AIDS (this)24%
Open-enrollment share among volume-matched conditions near HIV/AIDS

HIV/AIDS lists 15 open slots (24% of 62 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for HIV/AIDS on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. HIV/AIDS is recruiting below its size-band peers.

    15 of 62 indexed trials (24.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of HIV/AIDS trials is spread across many organizations.

    University of California, San Francisco accounts for 7 of 62 trials (11.3%). 38 distinct sponsors appear on at least one study for this condition label.

  3. Typical HIV/AIDS enrolment sits around 141 participants.

    Median target enrolment is 141 among the 62 trials that report a genuine target (sentinel values excluded). 25 of those (40.3%) plan for fewer than 100 participants.

  4. HIV/AIDS research is mostly interventional.

    53 interventional and 9 observational studies make up this index (85.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 22Phase 31

Open and recent trials

62 total, page 2 of 2

COMPLETED NA 40 participants

Trauma Informed Intervention to Support Engagement in HIV Care Among MSM (THRIVE+)

Massachusetts General Hospital

NCT05822206

COMPLETED NA 39 participants

Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use

Friends Research Institute

NCT03864653

COMPLETED NA 31 participants

HIV+ Substance Users Released From Jail

University of Texas Southwestern Medical Center

NCT03834779

COMPLETED NA 30 participants

HIV Reengagement and Assessment Mobile Program (Project RAMP)

University of North Carolina, Chapel Hill

NCT04151498

COMPLETED NA 28 participants

Youth Ending the HIV Epidemic

University of California, San Francisco

NCT05789875

COMPLETED Phase 1 26 participants

Relative Mitochondrial Toxicity of Tenofovir Alafenamide (TAF) vs. Tenofovir Disoproxil Fumarate (TDF)

University of California, Los Angeles

NCT03251144

COMPLETED 24 participants

Platelet Function on Abacavir and Tenofovir

University of California, Los Angeles

NCT03081572

COMPLETED NA 24 participants

The BRIDGES Project: Bridging Resources to Engage Women in Integrated HIV Care and Support Services

University of California, San Diego

NCT04295876

COMPLETED NA 21 participants

Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users

University of Washington

NCT03584282

COMPLETED NA 20 participants

Cognitive Behavioral Therapy to Treat Insomnia in Persons With HIV Infection

Indiana University

NCT03390114

COMPLETED NA 16 participants

Web-Based Cognitive Behavioral Stress Management for Latino Sexual Minority Men Living With HIV and Cancer

University of Miami

NCT03993054

COMPLETED Phase 1 13 participants

Study in Healthy Males to Measure Darunavir and Etravirine in Blood, Seminal Fluid, and Rectal Tissue

University of North Carolina, Chapel Hill

NCT00855088

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 2
Phase 3 1

Named interventions

Most-linked intervention names on HIV/AIDS records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Peer Navigation Behavioral
3 trials
MyPEEPS Mobile Behavioral
2 trials
Control Behavioral
2 trials
mHealth N'Gage mobile application Other
1 trials
PlusCare Device
1 trials
DOORS-CHW Intervention Behavioral
1 trials
Combined Contingency Management and Peer Navigation Behavioral
1 trials
The BRIDGES Project Intervention Behavioral
1 trials

US sites by state

Facility locations filed on HIV/AIDS trials. A trial with sites in several states counts in each.

California 16 trials
New York 9 trials
North Carolina 5 trials
Pennsylvania 4 trials
Maryland 4 trials
Massachusetts 4 trials
Illinois 4 trials
Georgia 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this HIV/AIDS page

62 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This HIV/AIDS condition card totals 62 registered trials; most-linked intervention Peer Navigation; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.