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NCT05789875 · ClinicalTrials.gov registry record · NA
Youth Ending the HIV Epidemic
A NA study of HIV/AIDS and Young Adults, sponsored by University of California, San Francisco.
- Completed
- Registry status
- NA
- Development phase
- 28
- Enrollment target
- 1
- Study location
NCT05789875: Completed NA study of HIV/AIDS and Young Adults, sponsored by University of California, San Francisco.
NCT05789875 is a NA study of HIV/AIDS and Young Adults that has completed, run by University of California, San Francisco. The registered enrollment target is 28 participants, below the 33,180-participant average among 61 other HIV/AIDS trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05789875, a NA study of HIV/AIDS and Young Adults, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- NA
- Development phase
- 28 participants
- Enrollment target
- 1
- Study location
Study Summary
Young adults have a disproportionately high rate of HIV infection, high rates of attrition at all stages of the HIV care continuum, an increased risk of antiretroviral therapy (ART) nonadherence and virologic failure, and a high probability of disease progression and transmission. Tracking and monitoring objective measures of ART adherence in real time is critical to strategies to support adherence and improve clinical outcomes. However, adherence monitoring often relies on self-reported and retrospective data or requires extra effort from providers to understand adherence patterns, making it difficult for providers to accurately determine how to support their patients in real time. In the proposed interventional study, the investigators aim to pilot test an automated directly observed therapy intervention paired with conditional economic incentives to improve ART adherence among youth living with HIV (YLWH) (18-29 years-old) who have an unsuppressed HIV viral load. Aim 1: Conduct a pilot study to assess feasibility and acceptability of the use of automated directly observed therapy with conditional economic incentives (aDOT-CEI) among YLWH (aged 18-29; N= 30) at AIDS Healthcare Foundation (AHF) clinics in California and Florida. Primary outcomes will be feasibility and acceptability, assessed using predefined feasibility metrics and acceptability surveys at three months. Aim 2: Explore experiences of YLWH and staff/providers with the aDOT-CEI intervention and implementation facilitators and barriers. The investigators will conduct in-depth qualitative interviews with a sample of YLWH from Aim 1 and staff/providers purposively selected from participating AHF clinics to explore intervention experiences, potential influences on ART adherence, individual-level and clinic-level barriers and facilitators to intervention implementation, and suggested refinements for a future efficacy trial. The investigators hypothesize that the aDOT-CEI intervention to improve ART adh
Primary Outcome
Rate of Participant Retention will be calculated as the percent of those who were retained in the study and completed the final survey.
Conditions Studied
Interventions
- OTHER aDOT-CEI
Study Locations (1)
California
- UCSF Center for AIDS Prevention Studies - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2023-01-31 |
| Est. Completion | 2023-09-08 |
| Phase | NA |
What the finished NCT05789875 record still lists
NCT05789875 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 33,180-participant average among 61 other HIV/AIDS trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with HIV/AIDS appearing as the primary indexed condition, and to 1 intervention - of which aDOT-CEI is the first listed.
NCT05789875 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05789875 about?
NCT05789875 is a clinical study titled "Youth Ending the HIV Epidemic". Young adults have a disproportionately high rate of HIV infection, high rates of attrition at all stages of the HIV care continuum, an increased risk of antiretroviral therapy (ART) nonadherence and virologic failure, and a high probability of disease progression and transmission. Tracking and monit...
What is the current status of trial NCT05789875?
This trial is currently completed. It is a NA study. The enrollment target is 28 participants. The study started on 2023-01-31. Estimated completion is 2023-09-08.
What conditions does trial NCT05789875 study?
This clinical trial studies the following conditions: HIV/AIDS, Young Adults, Mobile Health.
What interventions are being tested in trial NCT05789875?
The interventions under investigation include: aDOT-CEI (OTHER).
Who is sponsoring clinical trial NCT05789875?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05789875 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05789875's enrollment target sits among peer trials
28 54th of 61 higher than 8 of 61 other HIV/AIDS trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV/AIDS trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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