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Heart Failure, Diastolic: full-pipeline trial registry
6 of 15 indexed Heart Failure, Diastolic trials are currently recruiting.
Corpus placement: #1,140 of 28,707 conditions by registered trial count.
15 US clinical trials · 6 currently recruiting · #1,140 of 28,707 conditions by registered trial count
Heart Failure, Diastolic: 15 US clinical trials tracked, 6 recruiting.
Heart Failure, Diastolic is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Texas Southwestern Medical Center, running 3 of these trials.
Enrollment posture brief
Registry condition heart-failure-diastolic
OPEN 6 | RECR 40% | LATE 2 | EARLY 2 | RANK #1140 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)
Heart Failure, Diastolic lists 6 open slots (40% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Heart Failure, Diastolic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Heart Failure, Diastolic is recruiting below its size-band peers.
6 of 15 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Heart Failure, Diastolic research.
University of Texas Southwestern Medical Center accounts for 3 of 15 trials (20%). 13 distinct sponsors appear on at least one study for this condition label.
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Most Heart Failure, Diastolic trials plan to enrol fewer than 100 people.
Median target enrolment is 80 among the 15 trials that report a genuine target (sentinel values excluded). 10 of those (66.7%) plan for fewer than 100 participants.
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Heart Failure, Diastolic research is mostly interventional.
13 interventional and 2 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
15 total, page 1 of 1
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
Massachusetts General Hospital
NCT05577819
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Procyrion
NCT05677100
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
University of Virginia
NCT06009276
Pilot Study Lp299v Supplementation in Chronic Heart Failure
Medical College of Wisconsin
NCT05752760
Assessment of Left Ventricular Filling Pressure by Applying Artificial Intelligence Algorithms to Left Atrial Speckle-tracking Echocardiography
Istituto Auxologico Italiano
NCT05768698
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
Sardocor
NCT06061549
RESPONDER-HF Trial
Corvia Medical
NCT05425459
Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center
NCT04068844
AB-1002 in Patients With Class III Heart Failure
AskBio
NCT04179643
Hemodynamic-GUIDEd Management of Heart Failure
Abbott Medical Devices
NCT03387813
Exercise Intolerance in Elderly Patients With Diastolic Heart Failure
Wake Forest University
NCT00959660
Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction
Johns Hopkins University
NCT01901809
Improving Metabolic Health in Patients With Diastolic Dysfunction
University of Texas Southwestern Medical Center
NCT03448185
Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure
Mayo Clinic
NCT02145351
Impact of Empagliflozin on Functional Capacity in Heart Failure with Preserved Ejection Fraction
University of Texas Southwestern Medical Center
NCT05139472
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Heart Failure, Diastolic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Heart Failure, Diastolic trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Heart Failure, Diastolic page
15 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 6 Heart Failure, Diastolic trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Texas Southwestern Medical Center sponsors the most Heart Failure, Diastolic trials on record, review their full trial history before evaluating a specific study. See University of Texas Southwestern Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Heart Failure, Diastolic condition card totals 15 registered trials; most-linked intervention Pacemaker system will be implanted but set to Pacing Off.; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.