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NCT05677100 · ClinicalTrials.gov registry record · NA

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

A NA study of Heart Failure and Heart Failure, Congestive, sponsored by Procyrion.

Recruiting
Registry status
NA
Development phase
320
Enrollment target
20
Study locations

NCT05677100 is a NA study of Heart Failure and Heart Failure, Congestive that is actively recruiting participants, run by Procyrion. The registered enrollment target is 320 participants, below the 2,048-participant average among 397 other Heart Failure trials with a reported enrollment target (84% lower). The trial reports 20 study locations across 6 states.

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The verdict

NCT05677100, a NA study of Heart Failure and Heart Failure, Congestive, is actively recruiting participants, sponsored by Procyrion.

RECRUITING
Registry status
NA
Development phase
320 participants
Enrollment target
20
Study locations

Study Summary

Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failure (ADHF) and have persistent congestion despite usual medical therapy. Eligible ADHF patients with diuretic resistance (irrespective of ejection fraction) will be enrolled and randomized 1:1 to either the Aortix system or standard of care medical management.

Interventions

  • DEVICE Aortix System

Study Locations (20)

Florida

  • Ascension Sacred Heart - Pensacola
  • Tallahassee Research Institute - Tallahassee
  • University of South Florida - Tampa
  • BayCare Medical/St. Joseph's Hospital - Tampa
  • AdventHealth Tampa - Tampa
  • Cleveland Clinic Florida - Weston

California

  • John Muir Health - Concord
  • Zuckerberg San Francisco General - San Francisco
  • San Francisco Veterans Administration - San Francisco
  • University of California San Francisco - San Francisco

Arizona

  • Banner--University Medical Center Phoenix - Phoenix
  • Mayo Clinic - Arizona - Phoenix
  • HonorHealth Medical Center - Scottsdale

Georgia

  • Emory University Hospital - Atlanta
  • Piedmont Healthcare Inc. - Augusta
  • Wellstar Research Institue - Marietta

Illinois

  • University of Chicago - Chicago
  • Advocate IMMC - Chicago
  • Advocate Aurora - Good Samaritan - Downers Grove

Kansas

  • Ascension via Christi Kansas - Wichita

Trial Details

FieldValue
Enrollment Target 320 participants
Start Date 2023-08-23
Est. Completion 2027-08
Phase NA

Sponsor

Procyrion

2 total trials

What the Registry Record Tells You About NCT05677100

The ClinicalTrials.gov registry entry for NCT05677100 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 320 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,048-participant average among 397 other Heart Failure trials with a reported enrollment target (84% lower). The listed sponsor is Procyrion, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Aortix System is the first listed.

NCT05677100 reports 20 study locations spanning 6 distinct geographic areas - top geographies include Florida, California, Arizona.

Frequently Asked Questions

What is clinical trial NCT05677100 about?

NCT05677100 is a clinical study titled "Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure". Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failure (ADHF) and have persistent congestion despite usual medical therapy. Eligible ADHF patients with diuretic resistance (irrespective of ejec...

What is the current status of trial NCT05677100?

This trial is currently recruiting. It is a NA study. The enrollment target is 320 participants. The study started on 2023-08-23. Estimated completion is 2027-08.

What conditions does trial NCT05677100 study?

This clinical trial studies the following conditions: Heart Failure, Heart Failure, Congestive, Heart Failure, Diastolic, Heart Failure, Systolic, ADHF.

What interventions are being tested in trial NCT05677100?

The interventions under investigation include: Aortix System (DEVICE).

Who is sponsoring clinical trial NCT05677100?

This trial is sponsored by Procyrion, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05677100 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.