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NCT05577819 · ClinicalTrials.gov registry record · NA

Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

A NA study of Heart Failure and Amyloidosis, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
NA
Development phase
515
Enrollment target
1
Study location

NCT05577819 is a NA study of Heart Failure and Amyloidosis that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 515 participants, below the 2,048-participant average among 397 other Heart Failure trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05577819, a NA study of Heart Failure and Amyloidosis, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
NA
Development phase
515 participants
Enrollment target
1
Study location

Study Summary

Recent studies have shown that transthyretin amyloidosis (ATTR) can sometimes cause a type of heart failure where the pumping function of the heart is normal, also known as Heart Failure with Preserved Ejection Fraction (HFpEF) or diastolic heart failure. In this single center diagnostic study, we will evaluate for ATTR in patients with HFpEF in order to to determine how frequently this occurs and how we can predict which heart failure patients may have TTR amyloidosis. Our goal is to identify amyloidosis in heart failure patients earlier so that they can start treatment.

Interventions

  • DIAGNOSTIC_TEST 99mTc-pyrophosphate Scintigraphy

Study Locations (1)

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 515 participants
Start Date 2020-10-02
Est. Completion 2026-12-31
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT05577819

The ClinicalTrials.gov registry entry for NCT05577819 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 515 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,048-participant average among 397 other Heart Failure trials with a reported enrollment target (75% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which 99mTc-pyrophosphate Scintigraphy is the first listed.

NCT05577819 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05577819 about?

NCT05577819 is a clinical study titled "Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF". Recent studies have shown that transthyretin amyloidosis (ATTR) can sometimes cause a type of heart failure where the pumping function of the heart is normal, also known as Heart Failure with Preserved Ejection Fraction (HFpEF) or diastolic heart failure. In this single center diagnostic study, we w...

What is the current status of trial NCT05577819?

This trial is currently recruiting. It is a NA study. The enrollment target is 515 participants. The study started on 2020-10-02. Estimated completion is 2026-12-31.

What conditions does trial NCT05577819 study?

This clinical trial studies the following conditions: Heart Failure, Amyloidosis, Heart Failure, Diastolic, Transthyretin Amyloidosis.

What interventions are being tested in trial NCT05577819?

The interventions under investigation include: 99mTc-pyrophosphate Scintigraphy (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05577819?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05577819 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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