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NCT02145351 · ClinicalTrials.gov registry record · NA
Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure
A NA study of Heart Failure, Diastolic and Heart Failure With a Preserved Ejection Fraction, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT02145351: Completed NA study of Heart Failure, Diastolic and Heart Failure With a Preserved Ejection Fraction, sponsored by Mayo Clinic.
NCT02145351 is a NA study of Heart Failure, Diastolic and Heart Failure With a Preserved Ejection Fraction that has completed, run by Mayo Clinic. The registered enrollment target is 32 participants, below the 318-participant average among 14 other Heart Failure, Diastolic trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02145351, a NA study of Heart Failure, Diastolic and Heart Failure With a Preserved Ejection Fraction, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
Determine the impact of restoring normal heart rate response during exercise and daily activity in patients with heart failure and a preserved ejection fraction (HFpEF) and chronotropic incompetence (CI).
Primary Outcome
Maximal effort cardiopulmonary exercise testing was performed on a treadmill after 4 weeks of pacing-on and after 4 weeks of pacing-off to measure volumes of oxygen consumed (VO2). Change in VO2 at anaerobic threshold (VO2,AT) determined by the V-Slope method as the point of disproportionate rise in VCO2 relative to VO2 as measured in ml/kg/min.
Conditions Studied
Interventions
- DEVICE Rate adaptive atrial pacing using a dual-chamber pacemaker
- DEVICE Pacemaker system will be implanted but set to Pacing Off.
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2014-04-07 |
| Est. Completion | 2022-05-09 |
| Phase | NA |
What the finished NCT02145351 record still lists
NCT02145351 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 318-participant average among 14 other Heart Failure, Diastolic trials with a reported enrollment target (90% lower).
The record links to 3 conditions, with Heart Failure, Diastolic appearing as the primary indexed condition, and to 2 interventions - of which Rate adaptive atrial pacing using a dual-chamber pacemaker is the first listed.
NCT02145351 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT02145351 about?
NCT02145351 is a clinical study titled "Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure". Determine the impact of restoring normal heart rate response during exercise and daily activity in patients with heart failure and a preserved ejection fraction (HFpEF) and chronotropic incompetence (CI).
What is the current status of trial NCT02145351?
This trial is currently completed. It is a NA study. The enrollment target is 32 participants. The study started on 2014-04-07. Estimated completion is 2022-05-09.
What conditions does trial NCT02145351 study?
This clinical trial studies the following conditions: Heart Failure, Diastolic, Heart Failure With a Preserved Ejection Fraction, Chronotropic Incompetence.
What interventions are being tested in trial NCT02145351?
The interventions under investigation include: Rate adaptive atrial pacing using a dual-chamber pacemaker (DEVICE), Pacemaker system will be implanted but set to Pacing Off. (DEVICE).
Who is sponsoring clinical trial NCT02145351?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02145351 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure, Diastolic
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02145351's enrollment target sits among peer trials
32 10th of 14 higher than 5 of 14 other Heart Failure, Diastolic trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure, Diastolic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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