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NCT05752760 · ClinicalTrials.gov registry record · NA

Pilot Study Lp299v Supplementation in Chronic Heart Failure

A NA study of Heart Failure and Heart Failure With Preserved Ejection Fraction, sponsored by Medical College of Wisconsin.

Recruiting
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT05752760 is a NA study of Heart Failure and Heart Failure With Preserved Ejection Fraction that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 20 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05752760, a NA study of Heart Failure and Heart Failure With Preserved Ejection Fraction, is actively recruiting participants, sponsored by Medical College of Wisconsin.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to determine the impact of 12 weeks of Lp299v supplementation (20 million cfu/day vs. placebo) on exercise capacity, circulating biomarkers of cardiac remodeling, quality of life, and vascular endothelial function in humans with heart failure and reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) who have evidence of residual inflammation based on an elevated C-reactive protein level. This will be done in the setting of a randomized, double-blind, placebo-controlled trial.

Interventions

  • OTHER Lactobacillus Plantarum 299v Freeze Dried Capsule
  • OTHER Freeze Dried Potato Starch Capsule

Study Locations (1)

Wisconsin

  • Medical College of Wisconsin - Milwaukee

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2023-02-20
Est. Completion 2026-03-01
Phase NA

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT05752760

The ClinicalTrials.gov registry entry for NCT05752760 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (99% lower). The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Lactobacillus Plantarum 299v Freeze Dried Capsule is the first listed.

NCT05752760 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT05752760 about?

NCT05752760 is a clinical study titled "Pilot Study Lp299v Supplementation in Chronic Heart Failure". The goal of this study is to determine the impact of 12 weeks of Lp299v supplementation (20 million cfu/day vs. placebo) on exercise capacity, circulating biomarkers of cardiac remodeling, quality of life, and vascular endothelial function in humans with heart failure and reduced ejection fraction (...

What is the current status of trial NCT05752760?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2023-02-20. Estimated completion is 2026-03-01.

What conditions does trial NCT05752760 study?

This clinical trial studies the following conditions: Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Heart Failure, Diastolic, Heart Failure, Systolic.

What interventions are being tested in trial NCT05752760?

The interventions under investigation include: Lactobacillus Plantarum 299v Freeze Dried Capsule (OTHER), Freeze Dried Potato Starch Capsule (OTHER).

Who is sponsoring clinical trial NCT05752760?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05752760 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.