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NCT05752760 · ClinicalTrials.gov registry record · NA
Pilot Study Lp299v Supplementation in Chronic Heart Failure
A NA study of Heart Failure and Heart Failure With Preserved Ejection Fraction, sponsored by Medical College of Wisconsin.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05752760: Recruiting NA study of Heart Failure and Heart Failure With Preserved Ejection Fraction, sponsored by Medical College of Wisconsin.
NCT05752760 is a NA study of Heart Failure and Heart Failure With Preserved Ejection Fraction that is actively recruiting participants, run by Medical College of Wisconsin. The registered enrollment target is 20 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05752760, a NA study of Heart Failure and Heart Failure With Preserved Ejection Fraction, is actively recruiting participants, sponsored by Medical College of Wisconsin.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to determine the impact of 12 weeks of Lp299v supplementation (20 million cfu/day vs. placebo) on exercise capacity, circulating biomarkers of cardiac remodeling, quality of life, and vascular endothelial function in humans with heart failure and reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF) who have evidence of residual inflammation based on an elevated C-reactive protein level. This will be done in the setting of a randomized, double-blind, placebo-controlled trial.
Primary Outcome
This is a measurement of exercise capacity
Conditions Studied
Interventions
- OTHER Lactobacillus Plantarum 299v Freeze Dried Capsule
- OTHER Freeze Dried Potato Starch Capsule
Study Locations (1)
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2023-02-20 |
| Est. Completion | 2026-03-01 |
| Phase | NA |
What NCT05752760 shows while recruiting
NCT05752760 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (99% lower).
The record links to 5 conditions, with Heart Failure appearing as the primary indexed condition, and to 2 interventions - of which Lactobacillus Plantarum 299v Freeze Dried Capsule is the first listed.
NCT05752760 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT05752760 about?
NCT05752760 is a clinical study titled "Pilot Study Lp299v Supplementation in Chronic Heart Failure". The goal of this study is to determine the impact of 12 weeks of Lp299v supplementation (20 million cfu/day vs. placebo) on exercise capacity, circulating biomarkers of cardiac remodeling, quality of life, and vascular endothelial function in humans with heart failure and reduced ejection fraction (...
What is the current status of trial NCT05752760?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2023-02-20. Estimated completion is 2026-03-01.
What conditions does trial NCT05752760 study?
This clinical trial studies the following conditions: Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Heart Failure, Diastolic, Heart Failure, Systolic.
What interventions are being tested in trial NCT05752760?
The interventions under investigation include: Lactobacillus Plantarum 299v Freeze Dried Capsule (OTHER), Freeze Dried Potato Starch Capsule (OTHER).
Who is sponsoring clinical trial NCT05752760?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05752760 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05752760's enrollment target sits among peer trials
20 350th of 397 higher than 37 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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