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ClinicalTrials.gov 4 recruiting now official registry

AIDS clinical trials

4 of 15 indexed AIDS trials are currently recruiting.

15 US clinical trials · 4 currently recruiting

AIDS is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 2 of these trials.

The research picture

AIDS has 15 registered US clinical trials, 4 of them open to new participants right now, about 27% of the total.

4
recruiting participants now
27%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: GlaxoSmithKline
Phase 11Phase 22Phase 42

Active & Recent Trials

15 total, page 1 of 1

RECRUITING 19,000 participants

The DC Cohort Longitudinal HIV Status Neutral Study

George Washington University

NCT01206920

RECRUITING NA 275 participants

The Collaborative Care PrTNER Study

Children's Hospital of Philadelphia

NCT06585631

RECRUITING NA 110 participants

Economic Navigation and Strengthening to Research Unrestricted Services for Transgender Women (ENTRUST)

University of Central Florida

NCT06202898

RECRUITING 100 participants

Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV

Centers for Disease Control and Prevention

NCT06045923

COMPLETED NA 368 participants

CSP #512 - Options in Management With Anti-Retrovirals

US Department of Veterans Affairs

NCT00050089

COMPLETED Phase 2 191 participants

Efficacy and Safety of GSK Biologicals HIV Vaccine in Antiretroviral Therapy (ART)-naïve HIV-1 Infected Persons

GlaxoSmithKline

NCT01218113

COMPLETED Phase 1 190 participants

Long-term Follow-up of Participants From Studies Evaluating GSK HIV Vaccine

GlaxoSmithKline

NCT01092611

COMPLETED 100 participants

Neurocognitive Effects and Tolerability of Efavirenz in Aging HIV-infected Individuals ("SHAC Neuro Study")

Stanford University

NCT01985399

COMPLETED Phase 4 52 participants

Buprenorphine and Integrated HIV Care

Yale University

NCT00317460

COMPLETED NA 46 participants

Lower Extremity Splinting to Manage Pain and Sleep Disturbances Associated With HIV/AIDS Related Peripheral Neuropathy

Texas Woman's University

NCT01419314

COMPLETED NA 44 participants

Exercise and Pioglitazone for HIV-Metabolic Syndromes

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00639457

COMPLETED Phase 2 44 participants

Vitamin D Dose Finding Study

Children's Hospital of Philadelphia

NCT01092338

COMPLETED Phase 4 31 participants

Switching Undetectables to Selzentry

St. Hope Foundation

NCT01866267

COMPLETED NA 9 participants

Safety and Durability ofTenofovir and a Cell Cycle Agent for Viral Suppression

University of Maryland, Baltimore

NCT00344981

COMPLETED

HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers

National Cancer Institute (NCI)

NCT00491335

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the AIDS Trial Landscape

15 indexed AIDS studies · 4 recruiting (27%).

Phase mix: 2 late (III/IV) vs 3 early (I/II).

Top sponsor: GlaxoSmithKline (2 trials), 9 others listed. 15 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for AIDS?

PlainTrial tracks 15 US clinical trials for AIDS, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for AIDS?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.