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Healthy Volunteers: early-phase trial registry
79 of 284 indexed Healthy Volunteers trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #32 of 28,707 conditions by registered trial count.
284 US clinical trials · 79 currently recruiting · #32 of 28,707 conditions by registered trial count
Healthy Volunteers: 284 US clinical trials tracked, 79 recruiting.
Healthy Volunteers is the subject of 284 registered US clinical trials on ClinicalTrials.gov, 79 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 206 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 16 of these trials.
Enrollment posture brief
Registry condition healthy-volunteers
OPEN 79 | RECR 28% | LATE 6 | EARLY 206 | RANK #32 | SPON 16
Volume-matched condition peers
Nearest open-share peer: Arrhythmias, Cardiac (28% recruiting · 18 trials)
Healthy Volunteers lists 79 open slots (28% of 284 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Healthy Volunteers on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Healthy Volunteers is recruiting below its size-band peers.
79 of 284 indexed trials (27.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Healthy Volunteers trials is spread across many organizations.
Takeda accounts for 16 of 284 trials (5.6%). 144 distinct sponsors appear on at least one study for this condition label.
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Most Healthy Volunteers trials plan to enrol fewer than 100 people.
Median target enrolment is 48 among the 284 trials that report a genuine target (sentinel values excluded). 204 of those (71.8%) plan for fewer than 100 participants.
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Healthy Volunteers research is mostly interventional.
251 interventional and 33 observational studies make up this index (88.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
284 total, page 4 of 6
Cumulative Irritation Potential of 828 Ointment
Healthpoint
NCT00767455
A Study to Evaluate the Safety, Tolerability and Amount of EI-1071 in Blood in Healthy Volunteers
Elixiron Immunotherapeutics (Hong Kong)
NCT04238364
Photoallergy Potential of Dapsone Gel in Healthy Volunteers
Almirall, S.A.
NCT02117739
Evaluate Effects of Multiple Doses of Rifampin and Clarithromycin on the Single Dose Pharmacokinetics of Deflazacort
PTC Therapeutics
NCT02286635
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AJ302-IM in Healthy Volunteers
AnnJi Pharmaceutical Co.
NCT06625541
Study to Investigate the Effect of Balovaptan on the QTC Interval in Healthy Subjects
Hoffmann-La Roche
NCT03808298
A Study to Evaluate the Antibody Response of Influenza Vaccination Following Concomitant Exposure to Bimekizumab in Healthy Subjects
UCB Biopharma S.P.R.L.
NCT03895385
Study of AC0058TA in Healthy Male and Female Subjects
ACEA Therapeutics
NCT02847325
A Phase I Study in Healthy Volunteers to Assess the Effect of Cytochrome3A4 (CYP3A4) Inhibitors (Diltiazem and Itraconazole) on the Pharmacokinetics (PK) of AZD3293 and the Effects of AZD3293 on the Pharmacokinetics of Midazolam, a Cytochrome 3A4 and Cytochrome 3A5 (CYP3A4/CYP3A5) Substrate
AstraZeneca
NCT02010970
Drug-drug Interaction Study of Ozanimod With Pseudoephedrine to Evaluate the Effect on Blood Pressure and Heart Rate
Celgene
NCT03644576
A Study to Determine the Effect of Food on the Pharmacokinetics of PCI-32765
Janssen Research & Development
NCT01820936
A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components
Janssen Research & Development
NCT02073227
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00862433
Use of MRI for Assessing Stomach Relaxation in Response to a Meal
Mayo Clinic
NCT00275743
A Study to Investigate Different Formulations of S-337395 in Healthy Adult Participants
Shionogi
NCT06270511
Study to Assess the Safety and Tolerability of Ascending Single Doses of REGN2009 in Healthy Volunteers
Regeneron Pharmaceuticals
NCT01893528
Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ITI 333 in Healthy Volunteers
Intra-Cellular Therapies
NCT04934124
Japanese Pharmacokinetic Bridging Study for CC-93538
Celgene
NCT04096105
Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01950520
A Study to Access Safety, Tolerability, Pharmacokinetics(PK) and Pharmacodynamics(PD) of Orally Administered GCC-4401C in Healthy Volunteers
Green Cross Corporation
NCT01954238
Food Effect and Bioavailability of Deflazacort Formulations in Healthy Volunteers
PTC Therapeutics
NCT02485431
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of BMS-986278 and the Effects of BMS-986278 on Cardiac Repolarization in Healthy Participants
Bristol-Myers Squibb
NCT06746402
Safety Study of Efprezimod Alfa (CD24Fc, MK-7110) When Administered Intravenously in Healthy Adult Subjects (MK-7110-001)
Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT02650895
Compare the Same Dosage of Insulin Using a Combination of Cartridges, 30 Units as 2 Cartridges vs. 1 Cartridge
Mannkind Corporation
NCT01902121
Safety and Tolerability of Escalating Doses of BPN-14967 in Healthy Adults
Belite Bio
NCT04005807
A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet
Bristol-Myers Squibb
NCT03362411
A Study to Assess Safety, Tolerability, and Pharmacokinetics of CC-92480 Formulations in Healthy Adult Participants
Celgene
NCT04839809
A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes
Fontem US
NCT04429932
Civamide Patch Safety, Tolerability and PK Study
Winston Laboratories
NCT00758433
A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants
Spero Therapeutics
NCT05966688
A Study to Assess the Pharmacokinetics and Safety of CSL312 in Healthy Japanese and Caucasian Adults
CSL Behring
NCT04580654
Effects of Rehabilitation Robots-Morning Walk in Individuals With Hemiparesis
The University of Texas Medical Branch, Galveston
NCT06374706
A Open-label, Three-period, Partial-replicate Design Study to Evaluate the Inter- and Intrasubject Variability of the Avatrombopag To-be-marketed Formulation Administered as Single Doses of 40 mg to Healthy Subjects Receiving a Low-fat Meal
Eisai
NCT01759394
A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function
Takeda
NCT05098054
Safety, Tolerability, Pharmacokinetics of Intravenous RPX2003 (Biapenem) in Healthy Adult Subjects
Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company)
NCT01702649
ID-Cap System Under Direct Observation
EtectRX
NCT03475485
Evaluation of Changes to Skin Microbiome With Tape-Stripped Wounds
Johnson & Johnson Consumer Inc. (J&JCI)
NCT03365934
A Study of RGLS8429 in Healthy Volunteers
Regulus Therapeutics
NCT05429073
A Study to Assess the Safety and Tolerability of E2730 After Multiple Dose and the Food Effect After Single Dose in Healthy Participants
Eisai
NCT04676685
A Phase 1 Study to Assess Single and Multiple Ascending Doses of PBI-100 Topical Cream
Pyramid Biosciences
NCT05514353
A Study to Assess the Relative Bioavailability and Effect of Food on the Coated Granule Formulation of Mitapivat in Healthy Participants
Agios Pharmaceuticals
NCT04565678
A Study of Single Ascending Doses of IW-3300 in Healthy Volunteers
Ironwood Pharmaceuticals
NCT05188261
A Study to Assess the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamics of E2025 in Healthy Participants
Eisai
NCT05726851
A Study of Maribavir Pediatric Formulation in Healthy Adult Participants
Takeda
NCT05918822
Study of Lanadelumab in Healthy Japanese and Matched Caucasian Adult Subjects
Shire
NCT03401671
The Effects of GLA on Human Volunteers
Rockefeller University
NCT01397604
Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin
Amgen
NCT06207682
Effect of Rifampin and Efavirenz on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects
Celgene
NCT03983239
Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ITI 333 in Healthy Volunteers
Intra-Cellular Therapies
NCT05732194
A Study to Assess the Effect of Voriconazole and Quinidine on the Pharmacokinetics of a Single Dose of Repotrectinib in Healthy Participants
Bristol-Myers Squibb
NCT06493409
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 198 |
| Phase 2 | 8 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on Healthy Volunteers records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Healthy Volunteers trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Healthy Volunteers page
284 registered trials, 79 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 79 Healthy Volunteers trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Takeda sponsors the most Healthy Volunteers trials on record, review their full trial history before evaluating a specific study. See Takeda's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Volunteers condition card totals 284 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.