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NCT05966688 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants
A Phase 1 study of Healthy Volunteers, sponsored by Spero Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 39
- Enrollment target
- 1
- Study location
NCT05966688: Completed Phase 1 study of Healthy Volunteers, sponsored by Spero Therapeutics.
NCT05966688 is a Phase 1 study of Healthy Volunteers that has completed, run by Spero Therapeutics. The registered enrollment target is 39 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05966688, a Phase 1 study of Healthy Volunteers, has completed, sponsored by Spero Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 39 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary purpose of this study is to evaluate the pharmacokinetics (PK) of SPR720, azithromycin, and ethambutol, administered separately and co-administered, in healthy adult participants.
Conditions Studied
Interventions
- DRUG Azithromycin
- DRUG Ethambutol
- DRUG SPR720
Study Locations (1)
Ohio
- Medpace Clinical Pharmacology Unit - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2023-08-04 |
| Est. Completion | 2024-02-04 |
| Phase | Phase 1 |
What the finished NCT05966688 record still lists
NCT05966688 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (92% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 3 interventions - of which Azithromycin is the first listed.
NCT05966688 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05966688 about?
NCT05966688 is a clinical study titled "A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants". The primary purpose of this study is to evaluate the pharmacokinetics (PK) of SPR720, azithromycin, and ethambutol, administered separately and co-administered, in healthy adult participants.
What is the current status of trial NCT05966688?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 39 participants. The study started on 2023-08-04. Estimated completion is 2024-02-04.
What conditions does trial NCT05966688 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT05966688?
The interventions under investigation include: Azithromycin (DRUG), Ethambutol (DRUG), SPR720 (DRUG).
Who is sponsoring clinical trial NCT05966688?
This trial is sponsored by Spero Therapeutics, which has 14 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05966688 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05966688's enrollment target sits among peer trials
39 161st of 283 higher than 121 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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