Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04676685 · ClinicalTrials.gov registry record · Phase 1

A Study to Assess the Safety and Tolerability of E2730 After Multiple Dose and the Food Effect After Single Dose in Healthy Participants

A Phase 1 study of Healthy Volunteers, sponsored by Eisai.

Completed
Registry status
Phase 1
Development phase
32
Enrollment target
1
Study location

NCT04676685 is a Phase 1 study of Healthy Volunteers that has completed, run by Eisai. The registered enrollment target is 32 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04676685, a Phase 1 study of Healthy Volunteers, has completed, sponsored by Eisai.

COMPLETED
Registry status
Phase 1
Development phase
32 participants
Enrollment target
1
Study location

Study Summary

The primary purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of E2730 of multiple ascending oral doses in healthy adult participants and to assess the differences in PK, safety, and tolerability of E2730 between healthy Japanese and non-Japanese participants following multiple doses. This study will also determine the effect of food on PK of E2730.

Conditions Studied

Interventions

  • DRUG E2730
  • DRUG E2730-matched placebo

Study Locations (1)

California

  • Collaborative Neuroscience Research, LLC. - Long Beach

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2020-12-16
Est. Completion 2021-06-23
Phase Phase 1

Sponsor

Eisai

287 total trials

What the Registry Record Tells You About NCT04676685

The ClinicalTrials.gov registry entry for NCT04676685 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (93% lower). The listed sponsor is Eisai, which has 287 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 2 interventions - of which E2730 is the first listed.

NCT04676685 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT04676685 about?

NCT04676685 is a clinical study titled "A Study to Assess the Safety and Tolerability of E2730 After Multiple Dose and the Food Effect After Single Dose in Healthy Participants". The primary purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of E2730 of multiple ascending oral doses in healthy adult participants and to assess the differences in PK, safety, and tolerability of E2730 between healthy Japanese and non-Japanese participants fo...

What is the current status of trial NCT04676685?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2020-12-16. Estimated completion is 2021-06-23.

What conditions does trial NCT04676685 study?

This clinical trial studies the following conditions: Healthy Volunteers.

What interventions are being tested in trial NCT04676685?

The interventions under investigation include: E2730 (DRUG), E2730-matched placebo (DRUG).

Who is sponsoring clinical trial NCT04676685?

This trial is sponsored by Eisai, which has 287 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04676685 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteers

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.