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NCT02073227 · ClinicalTrials.gov registry record · Phase 1

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

A Phase 1 study of Healthy Volunteers, sponsored by Janssen Research & Development.

Completed
Registry status
Phase 1
Development phase
52
Enrollment target
1
Study location

NCT02073227 is a Phase 1 study of Healthy Volunteers that has completed, run by Janssen Research & Development. The registered enrollment target is 52 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02073227, a Phase 1 study of Healthy Volunteers, has completed, sponsored by Janssen Research & Development.

COMPLETED
Registry status
Phase 1
Development phase
52 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to assess the bioequivalence of the fixed dose combination (two components combined in one tablet) of canagliflozin and metformin extended release (XR) tablet (dose of 2 X 150 mg/1,000 mg) with respect to the individual components of canagliflozin (1 x 300 mg) and metformin XR tablet (4 x 500 mg) in healthy fed participants.

Conditions Studied

Interventions

  • DRUG Canagliflozin, 300 mg
  • DRUG Metformin XR, 500 mg
  • DRUG CANA/MET XR FDC, Formulation 1, 150 mg/1,000 mg
  • DRUG CANA/MET XR FDC, Formulation 2, 150 mg/1,000 mg

Study Locations (1)

Arizona

  • - Tempe

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2014-02
Est. Completion 2014-06
Phase Phase 1

Sponsor

Janssen Research & Development

593 total trials

What the Registry Record Tells You About NCT02073227

The ClinicalTrials.gov registry entry for NCT02073227 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (89% lower). The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 4 interventions - of which Canagliflozin, 300 mg is the first listed.

NCT02073227 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.

Frequently Asked Questions

What is clinical trial NCT02073227 about?

NCT02073227 is a clinical study titled "A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components". The purpose of this study is to assess the bioequivalence of the fixed dose combination (two components combined in one tablet) of canagliflozin and metformin extended release (XR) tablet (dose of 2 X 150 mg/1,000 mg) with respect to the individual components of canagliflozin (1 x 300 mg) and metfor...

What is the current status of trial NCT02073227?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2014-02. Estimated completion is 2014-06.

What conditions does trial NCT02073227 study?

This clinical trial studies the following conditions: Healthy Volunteers.

What interventions are being tested in trial NCT02073227?

The interventions under investigation include: Canagliflozin, 300 mg (DRUG), Metformin XR, 500 mg (DRUG), CANA/MET XR FDC, Formulation 1, 150 mg/1,000 mg (DRUG), CANA/MET XR FDC, Formulation 2, 150 mg/1,000 mg (DRUG).

Who is sponsoring clinical trial NCT02073227?

This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02073227 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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