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NCT07089875 · ClinicalTrials.gov registry record · Phase 3
A Study of Dotinurad Versus Allopurinol in Participants With Gout
A Phase 3 study of Gout, sponsored by Crystalys Therapeutics.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 500
- Enrollment target
- 20
- Study locations
NCT07089875: Recruiting Phase 3 study of Gout, sponsored by Crystalys Therapeutics.
NCT07089875 is a Phase 3 study of Gout that is actively recruiting participants, run by Crystalys Therapeutics. The registered enrollment target is 500 participants, below the 8,874-participant average among 34 other Gout trials with a reported enrollment target (94% lower). The trial reports 20 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07089875, a Phase 3 study of Gout, is actively recruiting participants, sponsored by Crystalys Therapeutics.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 500 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol in adult participants with hyperuricemia associated with gout.
Conditions Studied
Interventions
- DRUG Allopurinol
- DRUG Dotinurad
Study Locations (20)
California
- Medvin Clinical Research - Covina - Covina
- West Coast Research - Dublin
- Infinity Clinical Research - Norco
- Amicis Research Center - Balboa - Northridge
- Dream Team Clinical Research - Pomona
- Velocity Clinical Research - San Bernardino - San Bernardino
- Acclaim Clinical Research, Inc. - San Diego
- East Bay Rheumatology Medical Group - San Leandro
- BTC Network - Encompass Clinical Research - Spring Valley
- Cohen Medical Centers - Thousand Oaks
- Medvin Clinical Research - Tujunga - Tujunga
Arizona
- Arizona Arthritis & Rheumatology Associates (AARA) - Gilbert - Gilbert
- Arizona Arthritis & Rheumatology Associates (AARA) - Glendale - Glendale
- Arizona Arthritis & Rheumatology Associates (AARA) - Mesa - Mesa
- Del Sol Research Management - Tucson East - Tucson
- Del Sol Research Management - Tucson - Tucson
Alabama
- University of Alabama at Birmingham - Birmingham
- Alabama Clinical Therapeutics - Birmingham
Colorado
- Denver Arthritis Clinic - Lowry - Denver
Florida
- Bradenton Research Center - Bradenton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2025-08-01 |
| Est. Completion | 2027-11-29 |
| Phase | Phase 3 |
What NCT07089875 shows while recruiting
NCT07089875 is an interventional study that assigns participants to a tested intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap, below the 8,874-participant average among 34 other Gout trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Gout appearing as the primary indexed condition, and to 2 interventions - of which Allopurinol is the first listed.
NCT07089875 names 20 study sites across 5 states, led by California, Arizona, Alabama.
Frequently Asked Questions
What is clinical trial NCT07089875 about?
NCT07089875 is a clinical study titled "A Study of Dotinurad Versus Allopurinol in Participants With Gout". The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol in adult participants with hyperuricemia associated with gout.
What is the current status of trial NCT07089875?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 500 participants. The study started on 2025-08-01. Estimated completion is 2027-11-29.
What conditions does trial NCT07089875 study?
This clinical trial studies the following conditions: Gout.
What interventions are being tested in trial NCT07089875?
The interventions under investigation include: Allopurinol (DRUG), Dotinurad (DRUG).
Who is sponsoring clinical trial NCT07089875?
This trial is sponsored by Crystalys Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07089875 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gout
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07089875's enrollment target sits among peer trials
500 7th of 34 higher than 28 of 34 other Gout trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gout trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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