BioCryst Pharmaceuticals

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, BioCryst Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#553 of 15,742 sponsors by registered trial count).

29 total trials 2 currently recruiting 24 completed early-phase tilt top decile by trial count

BioCryst Pharmaceuticals: 29 sponsored US clinical trials, 2 recruiting.

BioCryst Pharmaceuticals sponsors 29 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 24 completed. 6 of these trials are in Phase 3-4 (later-stage) and 23 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Gout, with 2 trials.

Top-decile sponsor footprint

BioCryst Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#553 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 62/100

24 of 27 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

29 total, page 1 of 1

RECRUITING Phase 1

A Study of Avoralstat In Participants With Diabetic Macular Edema

NCT07228559

RECRUITING Phase 1

A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725

NCT06539507

COMPLETED Phase 1

A Study to Evaluate the Single Dose Safety, Tolerability and Pharmacokinetics of IV BCX4430

NCT03800173

COMPLETED Phase 2

A Long Term Safety Study of BCX7353 in Hereditary Angioedema

NCT03472040

COMPLETED Phase 3

Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAE

NCT03485911

COMPLETED Phase 3

Safety, PK and Effectiveness of IV Peramivir in Elderly and Higher Risk Subjects With Uncomplicated Influenza

NCT02635724

COMPLETED Phase 3

Safety, PK and Effectiveness of IV Peramivir Versus Oseltamivir in Pediatric Subjects With Uncomplicated Influenza

NCT02369159

COMPLETED Phase 2

12-Week Safety and Efficacy Study of BCX4161 as an Oral Prophylaxis Against HAE Attacks

NCT02303626

COMPLETED Phase 2

A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency

NCT01407874

COMPLETED Phase 2

Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to Allopurinol

NCT01265264

COMPLETED Phase 2

Study to Evaluate sUA-Lowering Activity, Safety & PK Interaction of Oral BCX4208 & Allopurinol Admin. in Subjects w/Gout

NCT01129648

TERMINATED Phase 3

A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza

NCT00958776

COMPLETED Phase 3

Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza

NCT00957996

COMPLETED Phase 2

Study to Evaluate the Urate-Lowering Activity and Safety of Oral BCX4208 Administered in Subjects With Gout

NCT00985127

COMPLETED Phase 2

A Phase II, Multicenter, Randomized, Placebo -Controlled, Study To Evaluate The Efficacy and Safety Of Intramuscular Peramivir 600 mg In Subjects With Uncomplicated Acute Influenza

NCT00705406

COMPLETED Phase 2

Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL)

NCT00640523

TERMINATED Phase 3

Intramuscular Peramivir in Subjects With Uncomplicated Acute Influenza

NCT00610935

COMPLETED Phase 2

Evaluation of Efficacy and Safety of Peramivir in Adults With Acute Serious or Potentially Life-threatening Influenza

NCT00453999

COMPLETED Phase 2

Forodesine in the Treatment of Cutaneous T-Cell Lymphoma

NCT00501735

COMPLETED Phase 2

Evaluation of the Efficacy and Safety of Peramivir in Subjects With Uncomplicated Acute Influenza.

NCT00419263

TERMINATED Phase 2

Study of Forodesine Hydrochloride in Patients With Relapsed/Refractory Precursor T-Lymphoblastic Leukemia/Lymphoma Who Have Failed Two or More Prior Treatment Regimens

NCT00419081

COMPLETED Phase 2

Study of Forodesine Hydrochloride in Patients With Advanced, Fludarabine-refractory Chronic Lymphocytic Leukemia (CLL)

NCT00289549

COMPLETED Phase 1

Forodesine (BCX-1777) in Treating Patients With Refractory Stage IIA, Stage IIB, Stage III, Stage IVA, or Stage IVB Cutaneous T-Cell Lymphoma

NCT00098332

COMPLETED Phase 1

Forodesine Hydrochloride (BCX-1777) for B-Cell Acute Lymphoblastic Leukemia

NCT00289562

COMPLETED Phase 2

Repeat-Dose of Forodesine Hydrochloride (BCX-1777) Infusion in Patients With Advanced T-Cell Leukemia

NCT00095381

COMPLETED Phase 1

BCX-1777 in Treating Patients With Refractory Cancer

NCT00073944

COMPLETED Phase 1

BCX-1777 in Treating Patients With Refractory Cutaneous T-Cell Lymphoma

NCT00061880

COMPLETED Phase 1

Study of Intravenous BCX-1777 in Relapsed or Refractory Aggressive T-Cell Leukemias or Lymphomas

NCT00035022

COMPLETED Phase 1

A Study of Peldesine (BCX-34) in HIV-Infected Patients

NCT00002237

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 14
Phase 3 6

What is open in the BioCryst Pharmaceuticals pipeline

2 recruiting of 29 indexed (7% open); 24 completed (83%).

Phase mix: 6 late (III/IV) vs 23 early (I/II) (early-phase heavy).

Top condition: Gout (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

BioCryst Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 29 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

BioCryst Pharmaceuticals sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400 0%20%40%60%80%100% Total trials Recruiting share BioCryst PharmaceuticalsBeOne MedicinesCalifornia Pacific Medical Center Research InstituteCenter for International Blood and Marrow Transplant ResearchCraig HospitalGenentechH. Lundbeck A/SAgios PharmaceuticalsWake Forest University
BioCryst Pharmaceuticals sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

BioCryst Pharmaceuticals sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 29 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this BioCryst Pharmaceuticals page

29 registered trials is a research-attention snapshot, not an endorsement of BioCryst Pharmaceuticals or any single study.

  • 2 of BioCryst Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Gout is the condition BioCryst Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Gout trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

BioCryst Pharmaceuticals pipeline card: 29 registered trials from official public datasets.Report a data error.