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End Stage Renal Disease clinical trials
25 of 88 indexed End Stage Renal Disease trials are currently recruiting.
88 US clinical trials · 25 currently recruiting
End Stage Renal Disease is the subject of 88 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University, running 4 of these trials.
The research picture
End Stage Renal Disease has 88 registered US clinical trials, 25 of them open to new participants right now, about 28% of the total.
- 25
- recruiting participants now
- 28%
- of trials open to enrollment
- 16
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Vanderbilt University
Active & Recent Trials
88 total, page 2 of 2
Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD
Medtronic Endovascular
NCT02363972
An Evaluation of IV Gamma Globulin As a Method to Improve Kidney Transplant Survival in Patients With End-Stage Renal Disease Who Are Highly Sensitized to Transplant Antigens
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00000935
Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation
Wright State University
NCT00906204
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
Ardelyx
NCT01764854
A Study to Evaluate the Safety and Efficacy of Paricalcitol Capsules in Reducing Serum Intact Parathyroid Hormone Levels in End Stage Renal Disease Subjects on Peritoneal Dialysis
Abbott
NCT00646035
C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI
Cedars-Sinai Medical Center
NCT02134314
End-Stage Renal Disease Intra-dialysis Lifestyle Education Study
Vanderbilt University Medical Center
NCT02361268
A Study Evaluating the Association of Inflammation With Hemodialysis Access Type
Montefiore Medical Center
NCT01011985
Effects of Hemodialysis on the Sleep/Wake Cycle
Emory University
NCT00460863
Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStage® System One™
NxStage Medical
NCT00667511
Effects of Oral Cholecalciferol (Vitamin D3) on Bone Health, Neuromuscular Function, and Quality of Life in Adults With Chronic Kidney Disease
Creighton University
NCT00511225
A Study to Evaluate the Effect of Renal Function on the Biological Activity of Telavancin
Cumberland Pharmaceuticals
NCT01238796
Use of Immune Globulin Plus Rituximab for Desensitization in Highly HLA Sensitized Patients Awaiting Deceased Donor Kidney Transplantation
Stanley Jordan, MD
NCT01178216
Thymoglobulin Versus Alemtuzumab Versus Daclizumab in Living Donor Renal Transplantation
University of Miami
NCT01046955
Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients
Duke University
NCT03781089
A Comparison of Physical Activity Levels With and Without Feedback Via Fitbit® Flex™ in Hemodialysis Patients
Renal Research Institute
NCT02320513
Inflammation, Proteolysis and IL-1 Beta Receptor Inhibition in Chronic Hemodialysis Patients
Vanderbilt University
NCT00420290
The Effects of Protein Supplementation and Resistance Exercise in Hemodialysis Patients
Vanderbilt University
NCT00179140
Study to Investigate the Pharmacokinetic Comparability of Dosing Triferic AVNU IV by Continuous Infusion and IV Bolus.
Rockwell Medical Technologies
NCT04409132
CellCept/Iron Study: The Iron Ion-Mycophenolate Mofetil Chelation Complex Interaction in Renal Allograft Recipients
University of Michigan
NCT00227045
The Effects of Resistance Exercise and Protein Supplementation in Hemodialysis Patients
Vanderbilt University
NCT00179218
Treatment Modification to Reduce Symptom Burden in Hemodialysis
The Rogosin Institute
NCT01775800
Study to Evaluate Daptomycin Given During Dialysis and After Dialysis
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT00882557
Safety and Dose Finding Study of Xigris in Hemodialysis Patients
George Washington University
NCT01227187
First Evaluation of the Moda-Flx Hemodialysis System™ in Real World Clinical Settings
Diality
NCT06581393
Triferic AVNU Infusion Via Freedom Pump During Hemodialysis
Rockwell Medical Technologies
NCT04689932
Acid-Base Composition With Use of hemoDialysates
Fresenius Medical Care North America
NCT02334267
The Effects of Nutrition Supplementation and Resistance Exercise During Hemodialysis
Vanderbilt University
NCT00179179
Trial of Adoptive Immunotherapy With TRACT to Prevent Rejection in Living Donor Kidney Transplant Recipients
Northwestern University
NCT02145325
A Pilot Study Using Autologous Regulatory T Cell Infusion Zortress (Everolimus) in Renal Transplant Recipients
Roberto Gedaly
NCT03284242
A Plant Based High Protein Diet to Improve Nutritional Outcomes in Peritoneal Dialysis Patients
Ochsner Health System
NCT02360748
Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5
University of Michigan
NCT02392208
Ertapenem Pharmacokinetics in Patients in Continuous Ambulatory Peritoneal Dialysis
Albany College of Pharmacy and Health Sciences
NCT00939952
Pharmacokinetics and Optimal Dose of Ertapenem in Hemodialysis Patients
Corewell Health East
NCT02159859
Plazomicin Study in ESRD Patients Receiving IHD
Cipla USA
NCT04699656
Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome
Johns Hopkins University
NCT01029587
Prevention of Kidney Transplant Rejection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00005010
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 14 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the End Stage Renal Disease Trial Landscape
88 indexed End Stage Renal Disease studies · 25 recruiting (28%).
Phase mix: 16 late (III/IV) vs 27 early (I/II).
Top sponsor: Vanderbilt University (4 trials), 9 others listed. 38 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for End Stage Renal Disease?
PlainTrial tracks 88 US clinical trials for End Stage Renal Disease, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for End Stage Renal Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.