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NCT04392206 · ClinicalTrials.gov registry record · Phase 1

AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses

A Phase 1 study of End Stage Renal Disease, sponsored by Houssam Farres, M.D..

Recruiting
Registry status
Phase 1
Development phase
15
Enrollment target
1
Study location

NCT04392206: Recruiting Phase 1 study of End Stage Renal Disease, sponsored by Houssam Farres, M.D..

NCT04392206 is a Phase 1 study of End Stage Renal Disease that is actively recruiting participants, run by Houssam Farres, M.D.. The registered enrollment target is 15 participants, below the 833-participant average among 86 other End Stage Renal Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04392206, a Phase 1 study of End Stage Renal Disease, is actively recruiting participants, sponsored by Houssam Farres, M.D..

RECRUITING
Registry status
Phase 1
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

Researchers are evaluating the safety of allogeneic Adipose Derived Mesenchymal Stem Cells (AMSC) use during hemodialysis arteriovenous fistula and arterial bypass creation and its efficacy on improving access maturation and primary anastomotic patency.

Primary Outcome

Evaluate the safety of AMSC administration by assessing the number of participants to experience an adverse event as defined by inflammation, infection (local or systemic), aneurysm formation, clinically significant increase or decrease in blood flow or thrombosis formation as evaluated through physical exam and ultrasound.

Conditions Studied

Interventions

  • DRUG Adipose Derived Mesenchymal Stem Cells

Study Locations (1)

Florida

  • Mayo Clinic in Florida - Jacksonville

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2020-05-15
Est. Completion 2027-06
Phase Phase 1
Houssam Farres, M.D.

1 total trials

What NCT04392206 shows while recruiting

NCT04392206 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 833-participant average among 86 other End Stage Renal Disease trials with a reported enrollment target (98% lower).

The record links to 1 condition, with End Stage Renal Disease appearing as the primary indexed condition, and to 1 intervention - of which Adipose Derived Mesenchymal Stem Cells is the first listed.

NCT04392206 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT04392206 about?

NCT04392206 is a clinical study titled "AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses". Researchers are evaluating the safety of allogeneic Adipose Derived Mesenchymal Stem Cells (AMSC) use during hemodialysis arteriovenous fistula and arterial bypass creation and its efficacy on improving access maturation and primary anastomotic patency.

What is the current status of trial NCT04392206?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2020-05-15. Estimated completion is 2027-06.

What conditions does trial NCT04392206 study?

This clinical trial studies the following conditions: End Stage Renal Disease.

What interventions are being tested in trial NCT04392206?

The interventions under investigation include: Adipose Derived Mesenchymal Stem Cells (DRUG).

Who is sponsoring clinical trial NCT04392206?

This trial is sponsored by Houssam Farres, M.D., which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04392206 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for End Stage Renal Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04392206's enrollment target sits among peer trials

15 74th of 86 higher than 13 of 86 other End Stage Renal Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other End Stage Renal Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04392206, the US trial registry maintained by the National Library of Medicine. NCT04392206 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.