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NCT04399941 · ClinicalTrials.gov registry record · NA
Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis
A NA study of End Stage Renal Disease, sponsored by Boston Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT04399941: Recruiting NA study of End Stage Renal Disease, sponsored by Boston Medical Center.
NCT04399941 is a NA study of End Stage Renal Disease that is actively recruiting participants, run by Boston Medical Center. The registered enrollment target is 50 participants, below the 833-participant average among 86 other End Stage Renal Disease trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04399941, a NA study of End Stage Renal Disease, is actively recruiting participants, sponsored by Boston Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Hemodialysis represents a life line of patients with end stage renal disease, who are commonly maintained on hemodialysis through catheters. Prolonged exposure to these catheters eventually damages the walls of veins, which results in stenosis at the local site. This condition is called central venous stenosis (CVS) and affects number of patients on hemodialysis in the United States and can compromise the dialysis efficacy. The current diagnostic modality for CVS is venography, which has several limitations. This study proposes to examine intravenous ultrasound (IVUS) as a potentially superior modality, which will provide additional information.
Primary Outcome
The severity of venous stenosis will be assessed using venogram and IVUS results. It will be calculated as the percentage diameter or area reduction, expressed as the ratio of the MLD or MLA to the RVD or RVA.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Venography
- DIAGNOSTIC_TEST Intravascular ultrasound (IVUS)
- OTHER Image processing
Study Locations (1)
Massachusetts
- Boston Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2021-08-03 |
| Est. Completion | 2026-09 |
| Phase | NA |
What NCT04399941 shows while recruiting
NCT04399941 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 833-participant average among 86 other End Stage Renal Disease trials with a reported enrollment target (94% lower).
The record links to 1 condition, with End Stage Renal Disease appearing as the primary indexed condition, and to 3 interventions - of which Venography is the first listed.
NCT04399941 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04399941 about?
NCT04399941 is a clinical study titled "Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis". Hemodialysis represents a life line of patients with end stage renal disease, who are commonly maintained on hemodialysis through catheters. Prolonged exposure to these catheters eventually damages the walls of veins, which results in stenosis at the local site. This condition is called central veno...
What is the current status of trial NCT04399941?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2021-08-03. Estimated completion is 2026-09.
What conditions does trial NCT04399941 study?
This clinical trial studies the following conditions: End Stage Renal Disease.
What interventions are being tested in trial NCT04399941?
The interventions under investigation include: Venography (DIAGNOSTIC_TEST), Intravascular ultrasound (IVUS) (DIAGNOSTIC_TEST), Image processing (OTHER).
Who is sponsoring clinical trial NCT04399941?
This trial is sponsored by Boston Medical Center, which has 253 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04399941 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for End Stage Renal Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04399941's enrollment target sits among peer trials
50 51st of 86 higher than 36 of 86 other End Stage Renal Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other End Stage Renal Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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