Ardelyx
Ardelyx sponsors 25 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 21 completed. 9 of these trials are in Phase 3-4 (later-stage) and 16 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Irritable Bowel Syndrome With Constipation (IBS-C), with 2 trials.
Trial Pipeline
25 total, page 1 of 1
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
NCT07382167
4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs
NCT06553547
Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years
NCT05643534
An Open-label Study to Evaluate the Pharmacokinetics of Oral Tenapanor in Breast Milk of Lactating Females
NCT06203444
A Study Evaluating the Safety and Efficacy of RDX013 for the Treatment of Hyperkalemia
NCT04780841
Study to Evaluate the Use of Tenapanor as Core Therapy in the Treatment of Hyperphosphatemia
NCT04549597
A Long-Term Study of Tenapanor Alone or in Combination With Sevelamer in Patients With CKD on Dialysis and HP
NCT03988920
Study to Evaluate the Efficacy of Tenapanor as Adjunctive Therapy to Phosphate Binder Therapy
NCT03824587
A Phase 3 Study of Tenapanor to Treat Hyperphosphatemia in ESRD Patients on Dialysis
NCT03427125
A Study Evaluating the Onset-of-Action, Safety, and Efficacy of RDX227675 for the Treatment of Hyperkalemia
NCT03018067
A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C
NCT02727751
An 8-Week Study to Evaluate Tenapanor in the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients on Hemodialysis (ESRD-HD)
NCT02675998
A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
NCT02686138
A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C
NCT02621892
To Evaluate the Effect of AZD1722 on the Pharmacokinetics of Oral Midazolam in Healthy Volunteers
NCT02140268
To Assess the Effect of AZD1722 on the Pharmacokinetics of Cefadroxil in Healthy Volunteers
NCT02140281
Dose Finding Study to Treat High Phosphate Levels in the Blood.
NCT02081534
The Efficacy of AZD1722 in Constipation Predominant Irritable Bowel Syndrome (IBS-C)
NCT01923428
Safety, Tolerability, Pharmacokinetics and Pharmacodynamic of AZD1722 in Healthy Male and Female Japanese Subjects
NCT02176252
A Study in CKD Patients With Type 2 Diabetes Mellitus and Albuminuria
NCT01847092
A Phase 1 Study to Examine the Effect of Renvela on the Pharmacodynamics of AZD1722
NCT02346890
D5611C00003 - Food Interaction Study With AZD1722 Tablet in Healthy Subjects
NCT02226783
A Phase 1 Study to Examine the Pharmacodynamics of Different AZD1722 Formulations
NCT02249936
Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
NCT01764854
A Study to Evaluate the Safety and Efficacy of RDX5791 for the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS-C)
NCT01340053
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 9 |
| Phase 3 | 7 |
| Phase 4 | 2 |
What the Pipeline for Ardelyx Shows
According to the ClinicalTrials.gov registry, Ardelyx is linked to 25 US clinical trials across every stage of research activity. Of those, 3 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 21 are already marked complete, representing roughly 84% of the total.
The phase mix for Ardelyx reports 9 late-stage studies (Phase 3 and Phase 4 combined) and 16 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Ardelyx is Irritable Bowel Syndrome With Constipation (IBS-C) with 2 linked trials, and 8 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.