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ClinicalTrials.gov 86 recruiting now official registry

Diabetes clinical trials

86 of 342 indexed Diabetes trials are currently recruiting.

342 US clinical trials · 86 currently recruiting

Diabetes is the subject of 342 registered US clinical trials on ClinicalTrials.gov, 86 of them currently open to new participants. 55 are in Phase 3-4 (later-stage) and 36 in Phase 1-2 (earlier-stage). The most active sponsor is Novo Nordisk A/S, running 41 of these trials.

The research picture

Diabetes has 342 registered US clinical trials, 86 of them open to new participants right now, about 25% of the total.

86
recruiting participants now
25%
of trials open to enrollment
55
in Phase 3–4 (later-stage)
41
top sponsor: Novo Nordisk A/S
Phase 123Phase 213Phase 337Phase 418

Active & Recent Trials

342 total, page 5 of 7

COMPLETED NA 223 participants

Diabetes Prevention Translation: the Healthy Lifestyle Project

University of Pittsburgh

NCT01050205

COMPLETED 207 participants

Glucose Risk Assessment in Employer Populations

DexCom

NCT04529824

COMPLETED 202 participants

Blood Glucose Monitoring System Clinical Study

Intuity Medical

NCT01327209

COMPLETED 200 participants

Real-world Aliskiren Use in Diabetic Patients

Novartis

NCT01393860

COMPLETED NA 200 participants

Using Patient Feedback to Improve Communication Regarding Glycemic Control to Patients With Diabetes

University of Pennsylvania

NCT01886170

COMPLETED Phase 4 200 participants

Diabetes Remote Intervention to improVe Use of Evidence-based Medications

Brigham and Women's Hospital

NCT06046560

COMPLETED NA 200 participants

Trial to Examine Text-message Based mHealth in Emergency Department Patients With Diabetes

University of Southern California

NCT01403831

COMPLETED NA 187 participants

Quality IQ Patient Simulation Physician Practice Measurement and Engagement

Qure Healthcare

NCT03800901

COMPLETED NA 184 participants

Hyperglycemic Profiles in Obstructive Sleep Apnea: Effects of PAP Therapy

Johns Hopkins University

NCT02454153

COMPLETED 175 participants

Accuracy of Hemoglobin A1C to Predict Glycemia in HIV

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00433628

COMPLETED NA 167 participants

Strong People Strength Training Study

Cornell University

NCT04203563

COMPLETED Phase 2 166 participants

TExT-MED + FANS Full Trial

University of Southern California

NCT03178773

COMPLETED NA 156 participants

Glucose Control Using 1,5-AG Testing

Qure Healthcare

NCT03765164

COMPLETED Phase 2 151 participants

A 12-week Titrate Study TO Evaluate Safety, Tolerability AND Pharmacodynamics OF PF-06882961 IN Adults With Type 2 Diabetes Mellitus AND IN Non-diabetic Adults With Obesity

Pfizer

NCT04617275

COMPLETED NA 150 participants

Addressing The Role of Nutrition Education & Health Literacy in Diabetes Care

Vanderbilt University

NCT00715585

COMPLETED Phase 4 150 participants

Diabetes in the Elderly: Prospective Study

Guillermo Umpierrez

NCT01131052

COMPLETED 150 participants

Lucica ® Glycated Albumin-L Clinical Program - Pivotal Study

Asahi Kasei Pharma Corporation

NCT02489773

COMPLETED NA 146 participants

Comparison Evaluation of Blood Glucose Meter Systems

Ascensia Diabetes Care

NCT01548885

COMPLETED 146 participants

Identifying Risk for Diabetes and Heart Disease in Women

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT01809288

COMPLETED Phase 2 145 participants

Health Beliefs, Glycemic Control, and Preventing Cognitive Decline in African Americans with Diabetes and Mild Cognitive Impairment: a Randomized Clinical Trial

Thomas Jefferson University

NCT04259047

COMPLETED Phase 3 143 participants

Switching From Insulin Glargine to Insulin Degludec in Subjects With Type 2 Diabetes Mellitus (BEGIN™)

Novo Nordisk A/S

NCT01135992

COMPLETED NA 139 participants

Implementing Diabetes Group Visits in Community Health Centers

University of Chicago

NCT02347514

COMPLETED NA 136 participants

Take Charge of Your Diabetes

University of Pennsylvania

NCT01977495

COMPLETED NA 135 participants

Expanding Comparative Effectiveness Research (CER) Capability Through Complex Patient Relationship Management

Denver Health and Hospital Authority

NCT01391585

COMPLETED NA 125 participants

Canola Oil Multi-Centre Intervention Trial II

University of Manitoba

NCT02029833

COMPLETED NA 123 participants

Performance of a New Glucose Meter System in Children and Young Adults

Ascensia Diabetes Care

NCT00985257

COMPLETED NA 118 participants

Combined Behavioral and Pharmacological Intervention for Cardiovascular Risk Reduction in Diabetic Patients

Providence VA Medical Center

NCT00357955

COMPLETED NA 118 participants

User Study of an Investigational Blood Glucose Monitoring System

Ascensia Diabetes Care

NCT01447121

COMPLETED NA 113 participants

Technology-assisted Case Management in Adults With Type 2 Diabetes

State University of New York at Buffalo

NCT01373489

COMPLETED NA 110 participants

Evaluation of the A1CNow+ Test Kit

Ascensia Diabetes Care

NCT00798486

COMPLETED NA 108 participants

Using Health Information Technology (HIT) to Improve Ambulatory Chronic Disease Care: Smart Device Substudy

University of Missouri-Columbia

NCT00802152

COMPLETED NA 105 participants

Dietary Approaches to Stop Hypertension for Diabetes

Johns Hopkins University

NCT04286555

COMPLETED NA 104 participants

Nourishing the Community Through Culinary Medicine

The University of Texas Health Science Center, Houston

NCT05624775

COMPLETED NA 100 participants

Remote Management of Diabetic Patients Via Data Transmission by Accu-Chek 360 Software

Columbus Research Foundation

NCT00956800

COMPLETED Phase 3 100 participants

Cystic Fibrosis - Insulin Deficiency, Early Action

Sydney Children's Hospitals Network

NCT01100892

COMPLETED 97 participants

A Complex Contraception Registry

University of California, San Diego

NCT02219269

COMPLETED NA 97 participants

Lifestyle Changes Through Exercise and Nutrition

Pennington Biomedical Research Center

NCT02863887

COMPLETED 92 participants

Urine pH as a Predictor of Diabetes

Northwell Health

NCT01017848

COMPLETED Phase 4 92 participants

Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

Temple University

NCT02088034

COMPLETED NA 91 participants

QBSAfe: A Novel Approach to Diabetes Management Focused on Quality of Life, Burden of Treatment, Social Integration and Avoidance of Future Events

Yale University

NCT04514523

COMPLETED 90 participants

Taste Perception and Chronic Disease Risk

Tufts University

NCT01023906

COMPLETED NA 89 participants

Nourishing the Community Through Culinary Medicine - Acres Homes

The University of Texas Health Science Center, Houston

NCT06096506

COMPLETED NA 88 participants

GLP1R Polymorphisms and Response to GLP1

Mayo Clinic

NCT00588380

COMPLETED NA 87 participants

Pilot Study on the Effects of a Plant-Strong Diet on Cardiovascular Risk Factors

Phoenix VA Health Care System

NCT03330548

COMPLETED NA 86 participants

Community Paramedicine Program to Improve Diabetes Care Quality, Equity, and Outcomes

Mayo Clinic

NCT04385758

COMPLETED Phase 4 83 participants

Novofine Autocover Safety Needle Versus BD Safety Glide

Novo Nordisk A/S

NCT00121355

COMPLETED Phase 4 83 participants

Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant

University of Minnesota

NCT01186562

COMPLETED 80 participants

Evaluation of Modified Adhesives With Dexcom G6 Sensor

DexCom

NCT04840446

COMPLETED NA 80 participants

Assessment of Glycemic Control in Patients With Type 2 Diabetes Mellitus and Late Stage Chronic Kidney Disease

Northwell Health

NCT03383627

COMPLETED Phase 2 79 participants

Improving Compliance With Metformin

US Department of Veterans Affairs

NCT00018616

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Phase Distribution

PhaseTrial count
Phase 1 23
Phase 2 13
Phase 3 37
Phase 4 18

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Diabetes Trial Landscape

342 indexed Diabetes studies · 86 recruiting (25%).

Phase mix: 55 late (III/IV) vs 36 early (I/II).

Top sponsor: Novo Nordisk A/S (41 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Diabetes?

PlainTrial tracks 342 US clinical trials for Diabetes, of which 86 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Diabetes?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.