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ClinicalTrials.gov 12 recruiting now full pipeline

Diabetes Type 2: full-pipeline trial registry

12 of 25 indexed Diabetes Type 2 trials are currently recruiting.

Corpus placement: #652 of 28,707 conditions by registered trial count.

25 US clinical trials · 12 currently recruiting · #652 of 28,707 conditions by registered trial count

Diabetes Type 2: 25 US clinical trials tracked, 12 recruiting.

Diabetes Type 2 is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Scripps Whittier Diabetes Institute, running 2 of these trials.

Enrollment posture brief

Registry condition diabetes-type-2

OPEN 12 | RECR 48% | LATE 4 | EARLY 4 | RANK #652 | SPON 2

Nearest open-share peer: GBM (48% recruiting · 25 trials)

Alpha-1 Antitrypsin Deficien48%Diabetes Type 2 (this)48%Alcohol Use40%Acute Lymphocytic Leukemia36%Alcohol-Related Disorders36%
Open-enrollment share among volume-matched conditions near Diabetes Type 2

Diabetes Type 2 lists 12 open slots (48% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Diabetes Type 2 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Diabetes Type 2 is recruiting above its size-band peers.

    12 of 25 indexed trials (48%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Diabetes Type 2 trials is spread across many organizations.

    Scripps Whittier Diabetes Institute accounts for 2 of 25 trials (8%). 21 distinct sponsors appear on at least one study for this condition label.

  3. Typical Diabetes Type 2 enrolment sits around 150 participants.

    Median target enrolment is 150 among the 25 trials that report a genuine target (sentinel values excluded). 7 of those (28%) plan for fewer than 100 participants.

  4. Diabetes Type 2 research is mostly interventional.

    22 interventional and 3 observational studies make up this index (88% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 22Phase 34

Open and recent trials

25 total, page 1 of 1

RECRUITING 10,000 participants

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility

Brooklyn Clinical Research

NCT06412536

RECRUITING Phase 1 600 participants

Pharmacogenetics of Response to GLP1R Agonists

University of Maryland, Baltimore

NCT05071898

RECRUITING NA 376 participants

Enhancing Diabetes Management Approaches for Patients With Uncontrolled Diabetes

University of Wisconsin, Madison

NCT05912647

RECRUITING NA 264 participants

RESET System Pivotal Trial (Rev F)

Morphic Medical

NCT04101669

RECRUITING NA 150 participants

Dulce Digital 2.0 - Innovative Diabetes Self-Management in the Digital Age

Scripps Whittier Diabetes Institute

NCT05416060

RECRUITING NA 140 participants

Enhancing Digitally Delivered Diabetes Education With Real-Time CGM

Scripps Whittier Diabetes Institute

NCT06296550

RECRUITING NA 120 participants

Healthy Living Anson Study

University of North Carolina, Chapel Hill

NCT07126587

RECRUITING NA 90 participants

FELLAShip to Better Health

University of Alabama at Birmingham

NCT07220213

RECRUITING NA 60 participants

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

Bettina Mittendorfer

NCT06335771

RECRUITING NA 60 participants

Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine

University of North Carolina, Chapel Hill

NCT07148713

RECRUITING NA 60 participants

Time-Restricted Eating for Type II Diabetes: TRE-T2D

University of California, San Diego

NCT05365529

RECRUITING 20 participants

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

Massachusetts General Hospital

NCT05799222

ACTIVE NOT RECRUITING NA 1,000 participants

Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)

Johns Hopkins University

NCT06347484

ACTIVE NOT RECRUITING 500 participants

Biological Sample Repository for Gastrointestinal Disorders

Pichamol Jirapinyo, MD, MPH

NCT05874726

ACTIVE NOT RECRUITING NA 116 participants

Impact of a Community Health Worker Strategy on Produce Prescription Program Uptake Among People With Diabetes

Yale University

NCT06401668

COMPLETED Phase 3 537 participants

Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

Eli Lilly and Company

NCT06354660

COMPLETED Phase 3 429 participants

A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine in Adults With Type 2 Diabetes

Novo Nordisk A/S

NCT06340854

COMPLETED NA 392 participants

Reducing Distress and Improving Self-Care in Diabetes

University of California, San Francisco

NCT00714441

COMPLETED Phase 3 365 participants

Comparison Study of the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly Suspension to Sitagliptin and Placebo in Subjects With Type 2 Diabetes Mellitus

AstraZeneca

NCT01652729

COMPLETED Phase 2 266 participants

Study Of Safety And Efficacy Of PF-04991532 In Subjects With Type 2 Diabetes Mellitus

Pfizer

NCT01336738

COMPLETED Phase 2 188 participants

Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus

Oramed

NCT02496000

COMPLETED Phase 3 123 participants

Lifestyle Interventions for Expectant Mothers (LIFE-Moms Phoenix) - Phoenix

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT01812694

COMPLETED NA 105 participants

Dietary Approaches to Stop Hypertension for Diabetes

Johns Hopkins University

NCT04286555

COMPLETED Phase 1 55 participants

Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT02107976

COMPLETED NA 5 participants

Cryovagotomy Diabetes Trial

Emory University

NCT04276051

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 3 4

Named interventions

Most-linked intervention names on Diabetes Type 2 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
Enhanced standard care Behavioral
1 trials
Computer Automated Self-Management and Problem Solving Therapy (CAPS) Behavioral
1 trials
Computer Automated Self-Management (CASM) Behavioral
1 trials
Lifestyle and Activities Education Program (LEAP-AHEAD) Behavioral
1 trials
Sitagliptin 100 mg Drug
1 trials
750 mg PF-04991532 Drug
1 trials
450 mg PF-04991532 Drug
1 trials

US sites by state

Facility locations filed on Diabetes Type 2 trials. A trial with sites in several states counts in each.

California 9 trials
Florida 6 trials
North Carolina 5 trials
Massachusetts 5 trials
Georgia 4 trials
Arizona 4 trials
South Carolina 3 trials
Ohio 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Diabetes Type 2 page

25 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Type 2 condition card totals 25 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.