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NCT06335771 · ClinicalTrials.gov registry record · NA
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity
A NA study of Healthy and Obesity, sponsored by Bettina Mittendorfer.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06335771 is a NA study of Healthy and Obesity that is actively recruiting participants, run by Bettina Mittendorfer. The registered enrollment target is 60 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06335771, a NA study of Healthy and Obesity, is actively recruiting participants, sponsored by Bettina Mittendorfer.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to evaluate the role of transcription factor EB (TFEB) in adipose (fat) tissue macrophages (ATM) in regulating adipose tissue and systemic metabolic function in obesity. The investigators will assess the differences in ATM lipid metabolism in people with metabolically abnormal obesity and lean individuals. Both groups will have: * screening visit * imaging (body composition testing - dual-energy x-ray absorptiometry (DEXA) scans, magnetic resonance imaging \[MRI\] and magnetic resonance spectroscopy \[MRS\] scans) * Overnight visit with intravenous infusion (IV), muscle, and fat tissue biopsies Participants with obesity will complete meetings with study team members for a weight loss intervention to achieve a 10% body weight loss.
Conditions Studied
Interventions
- OTHER Dietary consultation weight loss intervention
Study Locations (1)
Missouri
- University of Missouri School of Medicine - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-08-01 |
| Est. Completion | 2028-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06335771
The ClinicalTrials.gov registry entry for NCT06335771 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The listed sponsor is Bettina Mittendorfer, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Dietary consultation weight loss intervention is the first listed.
NCT06335771 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT06335771 about?
NCT06335771 is a clinical study titled "Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity". The goal of this study is to evaluate the role of transcription factor EB (TFEB) in adipose (fat) tissue macrophages (ATM) in regulating adipose tissue and systemic metabolic function in obesity. The investigators will assess the differences in ATM lipid metabolism in people with metabolically abnor...
What is the current status of trial NCT06335771?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-08-01. Estimated completion is 2028-03.
What conditions does trial NCT06335771 study?
This clinical trial studies the following conditions: Healthy, Obesity, Diabetes Type 2, Nonalcoholic Fatty Liver.
What interventions are being tested in trial NCT06335771?
The interventions under investigation include: Dietary consultation weight loss intervention (OTHER).
Who is sponsoring clinical trial NCT06335771?
This trial is sponsored by Bettina Mittendorfer, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06335771 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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