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COMPLETED Phase 3

A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine in Adults With Type 2 Diabetes

NCT06340854 · View on ClinicalTrials.gov ↗

Study Summary

This study compares insulin icodec, a new insulin taken once a week, to insulin glargine, an insulin taken once a day. The study medicine will be investigated in participants with type 2 diabetes. Participants will either get insulin icodec or insulin glargine. Which treatment participants get is decided by chance. Insulin icodec is the new medicine being tested, while insulin glargine is already approved and can be prescribed by doctors. Participants will get one injection of insulin icodec once a week, or one injection of insulin glargine once a day, depending on the treatment group participants are assigned into. Participants will use a pen with a small needle to inject the medicine under participants skin into participants thigh, upper arm or stomach.The study will last for about 9 months, but participants will only be taking the study medicine for 6 months.

Conditions Studied

Interventions

  • DRUG Insulin icodec
  • DRUG Insulin glargine

Study Locations (20)

Texas

  • Amarillo Medical Specialists — Amarillo
  • Velocity Clinical Res-Dallas — Dallas
  • Victorium Clinical Research — Houston
  • PlanIt Research, PLLC — Houston

California

  • Advanced Investigative Medicine, Inc. — Hawthorne
  • Scripps Whittier Diabetes Inst — La Jolla
  • Clinical Trials Research — Lincoln

Florida

  • Northeast Research Institute of Florida — Fleming Island
  • South Broward Research LLC — Miramar

North Carolina

  • PharmQuest Life Sciences LLC — Greensboro
  • Accellacare Wilmington — Wilmington

Georgia

  • Endo Res Solutions Inc — Roswell

Kansas

  • Cotton-Oneill Diabetes and End — Topeka

Minnesota

  • International Diabetes Center — Minneapolis

Missouri

  • Jefferson City Medical Group, PC — Jefferson City

Trial Details

FieldValue
Enrollment Target 429 participants
Start Date 2024-04-19
Est. Completion 2025-06-13
Phase Phase 3

Sponsor

Novo Nordisk A/S

189 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06340854

The ClinicalTrials.gov registry entry for NCT06340854 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 429 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Diabetes, Type 2 appearing as the primary indexed condition, and to 2 interventions — of which Insulin icodec is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06340854 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Texas, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06340854 about?

NCT06340854 is a clinical study titled "A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine in Adults With Type 2 Diabetes". This study compares insulin icodec, a new insulin taken once a week, to insulin glargine, an insulin taken once a day. The study medicine will be investigated in participants with type 2 diabetes. Participants will either get insulin icodec or insulin glargine. Which treatment participants get is de...

What is the current status of trial NCT06340854?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 429 participants. The study started on 2024-04-19. Estimated completion is 2025-06-13.

What conditions does trial NCT06340854 study?

This clinical trial studies the following conditions: Diabetes, Type 2. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06340854?

The interventions under investigation include: Insulin icodec (DRUG), Insulin glargine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06340854?

This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06340854 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Kansas, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial