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NCT00655980 · ClinicalTrials.gov registry record · NA

Vitamins in Nitrous Oxide Study

A NA study of Coronary Artery Disease and Major Surgery, sponsored by Washington University School of Medicine.

Completed
Registry status
NA
Development phase
687
Enrollment target
1
Study location

NCT00655980 is a NA study of Coronary Artery Disease and Major Surgery that has completed, run by Washington University School of Medicine. The registered enrollment target is 687 participants, below the 1,284-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (46% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00655980, a NA study of Coronary Artery Disease and Major Surgery, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
NA
Development phase
687 participants
Enrollment target
1
Study location

Study Summary

In this study, we want to find out if laughing gas (nitrous oxide) leads to a higher rate of cardiac complications after surgery in patients with a specific genetic profile (mutations in the MTHFR gene) and if this risk can be prevented by giving patients vitamin B12 and folate during surgery.

Interventions

  • OTHER standard of care
  • DRUG Vitamin B12 and folic acid
  • DRUG Nitrous oxide and placebo

Study Locations (1)

Missouri

  • Barnes-Jewish Hospital - St Louis

Trial Details

FieldValue
Enrollment Target 687 participants
Start Date 2008-02
Est. Completion 2016-12
Phase NA

What the Registry Record Tells You About NCT00655980

The ClinicalTrials.gov registry entry for NCT00655980 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 687 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,284-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (46% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 3 interventions - of which standard of care is the first listed.

NCT00655980 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT00655980 about?

NCT00655980 is a clinical study titled "Vitamins in Nitrous Oxide Study". In this study, we want to find out if laughing gas (nitrous oxide) leads to a higher rate of cardiac complications after surgery in patients with a specific genetic profile (mutations in the MTHFR gene) and if this risk can be prevented by giving patients vitamin B12 and folate during surgery.

What is the current status of trial NCT00655980?

This trial is currently completed. It is a NA study. The enrollment target is 687 participants. The study started on 2008-02. Estimated completion is 2016-12.

What conditions does trial NCT00655980 study?

This clinical trial studies the following conditions: Coronary Artery Disease, Major Surgery.

What interventions are being tested in trial NCT00655980?

The interventions under investigation include: standard of care (OTHER), Vitamin B12 and folic acid (DRUG), Nitrous oxide and placebo (DRUG).

Who is sponsoring clinical trial NCT00655980?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00655980 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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