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Colorectal Cancer: early-phase trial registry
162 of 394 indexed Colorectal Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #14 of 28,707 conditions by registered trial count.
394 US clinical trials · 162 currently recruiting · #14 of 28,707 conditions by registered trial count
Colorectal Cancer: 394 US clinical trials tracked, 162 recruiting.
Colorectal Cancer is the subject of 394 registered US clinical trials on ClinicalTrials.gov, 162 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 201 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 22 of these trials.
Enrollment posture brief
Registry condition colorectal-cancer
OPEN 162 | RECR 41% | LATE 13 | EARLY 201 | RANK #14 | SPON 22
Volume-matched condition peers
Nearest open-share peer: Erectile Dysfunction (41% recruiting · 34 trials)
Colorectal Cancer lists 162 open slots (41% of 394 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Colorectal Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Colorectal Cancer is recruiting above its size-band peers.
162 of 394 indexed trials (41.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Colorectal Cancer trials is spread across many organizations.
Memorial Sloan Kettering Cancer Center accounts for 22 of 394 trials (5.6%). 222 distinct sponsors appear on at least one study for this condition label.
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Typical Colorectal Cancer enrolment sits around 132 participants.
Median target enrolment is 132 among the 382 trials that report a genuine target (sentinel values excluded). 162 of those (42.4%) plan for fewer than 100 participants.
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Colorectal Cancer research is mostly interventional.
323 interventional and 71 observational studies make up this index (82% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
394 total, page 8 of 8
Growth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial Cancer
Vanderbilt-Ingram Cancer Center
NCT00897793
Skin Rash Study Before Chemotherapy in Colorectal & Head and Neck Cancer Patients
University of Louisville
NCT01874860
Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers
Mayo Clinic
NCT01950403
Radiolabeled Monoclonal Antibody in Treating Patients With Advanced Colorectal Cancer
Memorial Sloan Kettering Cancer Center
NCT00003360
Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer
Fox Chase Cancer Center
NCT00021398
Study Using Fluorine-18-Labeled Fluoro-Misonidazole Positron Emission Tomography to Detect Hypoxia in Locally Advanced (T3-T4 and./or N1)Primary Rectal Cancer Patients
Memorial Sloan Kettering Cancer Center
NCT00574353
Phase II Trial of RAD001 in Refractory Colorectal Cancer
Swedish Medical Center
NCT00337545
Lapatinib and Cetuximab in Patients With Solid Tumors
Georgetown University
NCT01184482
Irinotecan in Treating Patients With Metastatic or Recurrent Colorectal Cancer
Case Comprehensive Cancer Center
NCT00002933
Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Memorial Sloan Kettering Cancer Center
NCT00003543
A Study Comparing Oral Picoplatin With Intravenous Picoplatin in Subjects With Solid Tumors
Poniard Pharmaceuticals
NCT00465725
Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia
Pfizer
NCT04803305
Lymphatic Mapping and Sentinel Lymph Node Biopsy in the Treatment of Colorectal Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT00005640
Safety and Efficacy Study of BMS-908662 Alone or in Combination With Cetuximab in Subjects With K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal Cancer
Bristol-Myers Squibb
NCT01086267
Sorafenib, Pemetrexed, and Cisplatin in Treating Patients With Advanced Solid Tumors
Masonic Cancer Center, University of Minnesota
NCT00703638
Combination Chemotherapy and Oblimersen in Treating Patients With Advanced Colorectal Cancer
The University of Texas Health Science Center at San Antonio
NCT00055822
Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer)
Barbara Ann Karmanos Cancer Institute
NCT01420874
Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI
University of Massachusetts, Worcester
NCT02833753
Collection of Blood Specimens for Circulating Tumor Cell Analysis
Viatar
NCT01943500
Oxaliplatin With or Without Gefitinib in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer
University of Chicago
NCT00026299
Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
Case Comprehensive Cancer Center
NCT00005981
Monoclonal Antibody Therapy in Treating Patients With Colorectal Cancer
Memorial Sloan Kettering Cancer Center
NCT00005616
Bovine Lactoferrin in Reducing Taste Disturbances in Patients With Colorectal Cancer Receiving Oxaliplatin-Based Chemotherapy
Wake Forest University Health Sciences
NCT01596634
TMZ + Olaparib for MGMT Hypermethylated Colorectal Cancer
Yale University
NCT04166435
Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal Cancers
Holy Name Medical Center
NCT03604653
The Patient-Perspective of Complications After Colon and Rectum Surgery: A Qualitative Analysis
Memorial Sloan Kettering Cancer Center
NCT02836535
Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer
Memorial Sloan Kettering Cancer Center
NCT00550628
Colorectal Inflammatory Response to a Western-Style Diet
Rockefeller University
NCT00932308
TheraSphere® For Treatment of Metastases in Liver
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04517643
Irinotecan and Celecoxib in Treating Patients With Unresectable or Metastatic Colorectal Cancer
Roswell Park Cancer Institute
NCT00084721
Escalating Doses of Oxaliplatin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Children and Adolescents With Extensive Colon Carcinoma
M.D. Anderson Cancer Center
NCT02062749
Immunoscintigraphy Using Radiolabeled Monoclonal Antibody in Finding Tumor Cells in Patients With Colorectal Cancer
City of Hope Medical Center
NCT00647153
Gefitinib in Treating Patients With Recurrent Metastatic Colorectal Cancer
Eastern Cooperative Oncology Group
NCT00025350
Oxaliplatin in Treating Patients With Recurrent Metastatic Colorectal Cancer
Prologue Research International
NCT00017082
Gene Therapy in Treating Patients With Colon Cancer That Has Spread to the Liver
Memorial Sloan Kettering Cancer Center
NCT00012155
Oxaliplatin in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer
Roswell Park Cancer Institute
NCT00040820
Irinotecan in Treating Patients With Metastatic Colorectal Cancer
Memorial Sloan Kettering Cancer Center
NCT00003544
A Phase 2 Trial of ALIMTA (LY231514, Pemetrexed) Plus Oxaliplatin Administered Every 21 Days for First-Line Treatment of Patients With Advanced Colorectal Cancer.
Eli Lilly and Company
NCT00034619
Regional Native American Community Networks Program (RNACNP)
Washington State University
NCT02843217
Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer
National Cancer Institute (NCI)
NCT00103298
Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver
National Institutes of Health Clinical Center (CC)
NCT00020501
Surgery With or Without Radiofrequency Ablation Followed by Irinotecan in Treating Patients With Colorectal Cancer That is Metastatic to the Liver
University of Washington
NCT00030563
Combination Chemotherapy With Suramin Plus Doxorubicin in Treating Patients With Advanced Solid Tumors
Mayo Clinic
NCT00003038
Computerized Tomographic Colonography Compared With Standard Diagnostic Procedures in Detecting Colorectal Neoplasia
American College of Radiology Imaging Network
NCT00005809
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 132 |
| Phase 2 | 69 |
| Phase 3 | 10 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Colorectal Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Colorectal Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Colorectal Cancer page
394 registered trials, 162 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 162 Colorectal Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Memorial Sloan Kettering Cancer Center sponsors the most Colorectal Cancer trials on record, review their full trial history before evaluating a specific study. See Memorial Sloan Kettering Cancer Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Colorectal Cancer condition card totals 394 registered trials; most-linked intervention Cetuximab; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.